Clinical trials: Tracheal Diseases
Traumatic Brain Injury
Botulinum Toxin and Saliva Management in Tracheotomised Patients
TITLE A randomised placebo controlled trial to explore the effectiveness of Botulinum Toxin injection at reducing oral secretions and frequency of tracheal suctioning in tracheotomised patients.
- Trial name
- NCT00973999
- Testing
- Botulinum Toxin
- Where
- United Kingdom
- Sponsor
- HCA International Limited
Tracheomalacia, Tracheobronchomalacia
Tracheobronchomalacia: Treatment Outcomes
The purpose of this study is to evaluate respiratory symptoms and their impact in the quality of life and after treatment of the respiratory condition (tracheobronchomalacia - TBM).
- Trial name
- NCT00550602
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Beth Israel Deaconess Medical Center
Excessive Dynamic Airway Collapse, Tracheobronchomalacia
Symptomatic Treatment of Excessive Dynamic Airway Collapse Using Daytime Portable Continuous Positive Airway Pressure
The aim of this study is to assess the benefit of a portable ventilator generating positive end-expiratory pressure on exercise tolerance in patients with Excessive dynamic airway collapse (EDAC) and tracheobronchomalacia (TBM).
- Trial name
- EPOC (NCT02763631)
- Testing
- Experimental: Treatment, Experimental: Run In Phase
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Tracheobronchomalacia
Pressure Dependent Tracheal Obstruction in Copd Patients
Background. Do pressure dependent tracheal obstructions (PDTO) often seen during bronchoscopy in COPD patients affect pulmonary function tests and breathing symptoms? Method. Model study.
- Trial name
- PDTO (NCT01679808)
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- LHL Helse
Assess the Prediction of Successful SBT and Extubation of Trachea by Bedside Lung Ultrasound in Mechanically Ventilated Patients
Prediction of Weaning Outcome From Mechanical Ventilation Using Ultrasound
Examine the predictive value of lung ultrasound in assessing the success of SBTs and tracheal extubation among patients receiving mechanical ventilation in the intensive care unit (ICU).
- Trial name
- NCT06685224
- Testing
- Ultrasound Assessment of the aeration of lung tissue and Parasternal Intercostal Muscle Thickness
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tanta University
Chronic Anemia
The Effect of Chronic Anemia on Safety Period of Tracheal Intubation in Gynecology Patients
1. Every individual receiving a general anesthetic is at potential risk for developing a ''cannot intubate-cannot ventilate'' situation following anesthetic induction. 2.
- Trial name
- NCT01968525
- Testing
- pre-oxygen
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Fudan University
Tracheal Stenosis
DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis
Multicenter randomized controlled trial comparing endoscopic laser resection vs dilatation in benign tracheal stenosis.
- Trial name
- AERATE (NCT04719845)
- Testing
- Endoscopic laser resection, Dilatation
- Where
- 4 sites in Canada, France
- Volunteers
- 108 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Excessive Central Airways Collapse, Respiratory Disease
Portable Continuous Positive Airways Pressure (CPAP) in Excessive Central Airway Collapse (ECAC) Study
This study will investigate the role of a portable Continues Positive Airway Pressure device (pCPAP) in management of patients with symptomatic Excessive Central Airway Collapse (ECAC).
- Conditions
- Excessive Central Airways Collapse, Respiratory Disease, Tracheobronchomalacia, Excessive Dynamic Airway Collapse
- Trial name
- NCT06072872
- Testing
- Use of portable CPAP
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Lung Neoplasms
Effects of Nonintubated Versus Intubated General Anesthesia on Recovery After Thoracoscopic Lung Resection
Lung cancer is the leading cause of cancer death in Taiwan and worldwide. With the advancement of thoracoscopic technique, thoracoscopic surgery has emerged as a reasonable option for the management of early-stage non-small cell…
- Trial name
- NCT02393664
- Testing
- propofol, bupivacaine, sevoflurane, rocuronium
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- National Taiwan University Hospital
Airway Obstruction, Difficult Intubation
Evaluation of the Use of Tracheal Intubation Through a Laryngeal Tube to Intubate Anesthetized Patients
Failed intubation is currently one of the most important factors leading to morbidity and mortality in anesthesia. The development of supraglottic airway devices (SGDs), such as the intubating laryngeal tube, has revolutionized…
- Trial name
- IKING (NCT03165461)
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Formacion Internacional para la Docencia e Investigación de la Vía Aérea
Acute Respiratory Failure
Tube Size Randomized Trial During Emergency Tracheal Intubation
The BREATHE trial is a parallel-group, pragmatic, randomized clinical trial comparing the effectiveness of smaller versus larger endotracheal tubes for mechanical ventilation of critically ill adults at 7 geographically diverse…
- Trial name
- BREATHE (NCT06939361)
- Testing
- Smaller endotracheal tube, Larger endotracheal tube
- Where
- 7 sites in United States
- Volunteers
- 3,180 people
- Sponsor
- Vanderbilt University Medical Center
Tracheal Intubation, Infection
Comparison of VieScope vs. Macintosh Laryngoscope for Intubation in Level Cpersonal Protective Equipment Conditions
The current COVID-19 pandemic, this is especially since the transmission of SARS-CoV-2 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, by direct contact with contaminated surfaces and…
- Conditions
- Tracheal Intubation, Infection, Projection
- Trial name
- NCT04363775
- Testing
- The standard Macintosh laryngoscope, The Vie Scope laryngoscope
- Where
- Poland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Lazarski University
Intubation, Cardiac Arrest
Pediatric Difficult Intubation
Endotracheal intubation (ETI) is perceived as the optimal method of providing and maintaining a clear and secure airway. The 2010 European Resuscitation Council (ERC) guidelines emphasized the importance of minimal interruption…
- Trial name
- 3V-L DL (NCT02295670)
- Testing
- Vividtrac, MIL
- Where
- Poland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Mechanical Ventilation Complication, Pediatric Respiratory Diseases
Tracheal Suctioning With or Without Expiratory Pause Maneuver in Children
The purpose of this study is to evaluate the efficacy of tracheal suctioning associate with expiratory pause maneuver in children on invasive mechanical ventilation.
- Trial name
- NCT05805475
- Testing
- Endotracheal suctioning with expiratory pause, Endotracheal suctioning without expiratory pause
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Trachebronchomalacia (TBM), Hyper Dynamic Airway Collapse (HDAC)
Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea
The investigators hypothesize that there is a strong correlation between OSA and TBM/HDAC. Our hypothesis is based on the similarities in mechanism (airway collapse), symptoms (daytime and nocturnal dyspnea) predisposing…
- Conditions
- Trachebronchomalacia (TBM), Hyper Dynamic Airway Collapse (HDAC), Obstructive Sleep Apnea (OSA)
- Trial name
- NCT02097212
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Jewish Health
Respiratory Disease, Tracheal Stenosis
Total Intravenous Anesthesia for Rigid Bronchoscopy Using Remimazolam
Rigid bronchoscopy usually requires deep general anesthesia, but the duration of the procedure is relatively short. Remimazolam, a recently developed anesthetics, showed faster recovery from anesthesia and stable hemodynamics…
- Conditions
- Respiratory Disease, Tracheal Stenosis, Endobronchial Mass
- Trial name
- NCT05835713
- Testing
- Remimazolam besylate, Propofol
- Sponsor
- Samsung Medical Center
Ventilator Associated Pneumonia, Pneumonia, Bacterial
Cultures in PICU Patients Compared to Healthy Children
This study is being done to determine if the bacteria found in your mouth (oral flora bacteria) in children admitted to the intensive care unit who need to be on a breathing machine is different from the oral flora in healthy…
- Trial name
- NCT03418272
- Testing
- Culture/PCR Analysis
- Sponsor
- State University of New York at Buffalo
Cardiac Arrest
Videolaryngoscopy During Child Intubation
We hypothesized that the video-laryngoscopes are beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of three video-laryngoscopes and Macintosh (MAC) laryngoscopes…
- Trial name
- NCT02289664
- Testing
- MAC, Coopdech, CoPilot
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Coronary Disease Undergoing CABG
Assessment of Hemodynamic Response During Intubation Between Rigid Laryngoscopy and Track Light in Coronary Patients
Opioids provide greater patient comfort during intubation, but are not able to abolish completely the release adrenergic hormones during the laryngoscopy, which may cause undesirable hemodynamic changes.
- Trial name
- NCT01682707
- Testing
- laryngoscopy, track light
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Juiz de Fora
Congenital Diaphragmatic Hernia
North American Fetal Therapy Network for Long-term Outcome Following Fetoscopic Endoluminal Tracheal Occlusion in Severe Left and Right Congenital Diaphragmatic Hernia
The purpose of this study is to evaluate successful placement and removal of Fetoscopic Endoluminal Tracheal Occlusion (FETO) device in cases of intrathoracic liver herniation with isolated left congenital diaphragmatic hernia…
- Trial name
- NCT06739356
- Testing
- Fetal Treatment arm (FETO Group)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston