Clinical trials: Tracheal Intubation in ICU
Postoperative Pulmonary Complications
Postoperative Pulmonary Complications in Major Abdominal Surgery
Incidence of Postoperative Pulmonary Complications (PPCs) varies from 2% to 19%, according to the population under examination and the criteria used to define pulmonary complications. There is no univocal definition of PPCs.
- Trial name
- NCT01701908
- Where
- 40 sites in Italy
- Volunteers
- 1,542 people
- Sponsor
- University of Udine
Intubation in Intensive Care Units
Delayed Against Rapid Sequence Induction in Adults With Medical Diseases Undergoing Emergency Endotracheal Intubation.
The goal of this clinical trial is to learn if it is feaseble to conduct a superiority trial comparing two methods for endotracheal intubation in critically ill patients.
- Trial name
- DARSITUBE (NCT06940219)
- Testing
- Delayed Sequence Induction, Modified Rapid Sequence Induction
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Leipzig University Medical Center
Cuff Overinflation, Cuff Underinflation
Cuff Pressure Regulation Apparatus for Tracheal Intubation in Children
Despite the expert recommendation about rigorous monitoring of tracheal cuff pressure using a continuous or intermittent technique, cuff underinflation and overinflation are common increasing the risk of microinhalation and…
- Trial name
- CPRATIC-2 (NCT04413318)
- Testing
- Electronic device (VBM©), Pneumatic device (Nosten©)
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Critical Illness, Airway Management Assessment
INTUPROS 2-3: Improving First-Pass Intubation Success and Reducing Complications in ICU Patients
This national, multicenter, prospective cohort study aims to determine the prevalence and risk factors associated with major peri-intubation complications in critically ill adult patients undergoing tracheal intubation in…
- Conditions
- Critical Illness, Airway Management Assessment, Tracheal Intubation, Complications
- Trial name
- INTUPROS (NCT07807358)
- Volunteers
- 1,300 people
- Sponsor
- Spanish Society of Critical Care Medicine and Coronary Units
Mechanical Ventilation, Tracheal Intubation
Simple Mechanical Device to Control Pressure in the Balloon of the Endotracheal Tube to Prevent Ventilator-acquired Pneumonia
Hypothesis: Nosten® device is able to reduce the time of underinflated balloon and removes excess pressure. This device may thus reduce the risk of ventilator-acquired pneumonia (VAP) and early tracheal lesions resulting from…
- Conditions
- Mechanical Ventilation, Tracheal Intubation, Ventilator-acquired Pneumonia, Intubation -Related Tracheal Lesions
- Trial name
- PAV-PROTECT (NCT02514655)
- Testing
- Nosten® pressure control (it's not an antibiotic, but simple device), Manual pressure control
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Respiratory Failure, Intubation
Hyperangulated vs Macintosh Blades for Intubation With Videolaryngoscopy in ICU
Tracheal intubation in the intensive care unit (ICU) is associated with high incidence of difficult intubation and complications.
- Conditions
- Acute Respiratory Failure, Intubation, Intubation; Difficult or Failed, Videolaryngoscopy
- Trial name
- INVIBLADE (NCT06322719)
- Testing
- Hyperangulated blade videolaryngoscope, Macintosh blade videolaryngoscope
- Where
- 29 sites in Spain
- Volunteers
- 1,036 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Pain, Analgesia
EUROpean Pain Audit In Neonates
EUROPAIN Survey is an epidemiological study aimed at assessing current clinical practices regarding the use of sedative and analgesic drugs in newborns admitted to NICUs or PICUs in different countries in Europe.
- Conditions
- Pain, Analgesia, Sedation, Intesive Care
- Trial name
- EUROPAINsurvey (NCT01694745)
- Where
- 242 sites in Austria, Belgium and 16 more
- Volunteers
- 6,489 people
- Sponsor
- Hôpital Armand Trousseau
Acute Respiratory Failure, Intratracheal Intubation
Comparison of Pre-oxygenation of NIV and HFNC Therapy for Intubation of ICU Patients With Acute Respiratory Failure
The aim of the study is to evaluate the incidence of severe hypoxemia episodes during the intubation procedure with two methods of pre-oxygenation: 1. NIV (Non Invasive Ventilation) 2. HFNC (High-flow nasal canula oxygen therapy)
- Trial name
- FLORALI2 (NCT02668458)
- Testing
- High Flow nasal canula oxygen therapy, Noninvasive ventilation
- Where
- 27 sites in France
- Volunteers
- 320 people
- Sponsor
- Poitiers University Hospital
Intubation; Difficult or Failed, Intubation Complication
Adverse Events in the Tracheal Intubation in the Intensive Care Unit
The airway management is essential in the Critical Care setting, both normal and difficult airway patients. Intubation is a risk procedure in which a great number of complications may occur, including death.
- Conditions
- Intubation; Difficult or Failed, Intubation Complication, Intubation
- Trial name
- INTUPROS (NCT03916224)
- Where
- Spain
- Volunteers
- 1,800 people
- Sponsor
- Spanish Network for Research in Infectious Diseases
Respiratory Failure
Facilitating EndotracheaL Intubation by Laryngoscopy Technique and Apneic Oxygenation Within the Intensive Care Unit: The FELLOW Study
Respiratory failure requiring endotracheal intubation occurs in as many as 40% of critically ill patients. Procedural complications including failed attempts at intubation, esophageal intubation, arterial oxygen desaturation…
- Trial name
- FELLOW (NCT02051816)
- Testing
- Video Laryngoscopy, Apneic Oxygenation, Direct Laryngoscopy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Vanderbilt University
Respiratory Distress Syndrome in Premature Infant
Surfactant Therapy Via Supraglottic Airway to Preterm Neonates With RDS in Vietnam
Preterm babies often have trouble breathing because their lungs are not fully developed. This condition is called respiratory distress syndrome (RDS). A medicine called surfactant helps their lungs open up and work better.
- Trial name
- NEOSURF (NCT07098910)
- Testing
- Surfactant Administration Through Laryngeal or Supraglottic Airways (SALSA), Intubation - Surfactant administration - Extubation (INSURE)
- Where
- Vietnam
- Volunteers
- 440 people
- Sponsor
- Karolinska Institutet
Critically Ill Adults Requiring Emergency Tracheal Intubation in the Intensive Care Unit
Propofol or Esketamine: Tracheal Intubation Comparison
The goal of this clinical trial is to compare how esketamine and propofol affect blood pressure in critically ill adults who need a breathing tube in an intensive care unit (ICU).
- Trial name
- POETIC (NCT07847255)
- Testing
- Esketamine, Propofol
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Videolaryngoscopy, Intensive Care Unit Syndrome
Awake Tracheal Intubation in Critical Care Patients
Tracheal intubation in critical care is a high-risk procedure requiring significant expertise and airway strategy modifications, such as awake intubation with video laryngoscope or flexible endoscope intubation.
- Trial name
- Awake (NCT05802316)
- Testing
- tracheal intubation using videolaryngoscope with a hyperangulated blade or standard intubation videolaryngoscopy (VL) and direct laryngoscopy (DL)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Johannes Gutenberg University Mainz
Tongue Edema, Tongue Enlarged
Tongue Edema Caused by Intubation Tube in Intensive Care Unit Patients
Tongue edema (TE) is an enlargement of the tongue that can be noticed with the naked eye and protrudes from the mouth. Endotracheal intubation tube, which can exert high pressure on the tongue for a long time, may cause TE.
- Conditions
- Tongue Edema, Tongue Enlarged, Mechanical Ventilation Complication, Intubation Complication
- Trial name
- NCT05249738
- Testing
- Measuring tongue cross-sectional area by submental ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Selcuk University
High Flow Oxygen Therapy, Neuro ICU
HFTO Via Tracheal Intubation in Neurocritical Patients
Neurocritical patients often require prolonged invasive ventilation due to impaired respiratory drive and airway protection deficits.
- Trial name
- NCT07257016
- Testing
- HFTO, PSV
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Capital Medical University