Clinical trials: Tracheostomy
Tracheostomy
Safe and Effective Above Cuff Tracheostomy Ventilation
A Phase I study of an 'in-house' developed, novel, Class I, prototype medical device to facilitate vocalisation in participants with cuff-inflated tracheostomy tubes.
- Trial name
- SEACtV (NCT04647786)
- Testing
- Prototype medical device (SEA CtV)
- Where
- United Kingdom
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Stroke, Tracheotomy Patients
Study on the Correlation Mechanism and Application of Genetic Susceptibility, Hemoglobin Adaptation Changes, and Extubation Success Rate in Stroke Patients With Tracheotomy at Different Altitudes
Patients with brain injuries caused by various reasons often need tracheotomy to improve breathing, but this procedure can cause the air to lose its nasal regulation, increase the risk of lung infections, and reduce their quality…
- Trial name
- NCT07014501
- Testing
- High altitude, Medium altitude, Low altitude group
- Where
- China
- Volunteers
- 717 people
- Sponsor
- The Second Affiliated Hospital of Kunming Medical University
Tracheostomy Patients, Multidisciplinary Care Team
Evaluation of a Specialised Tracheostomy Team for the Management of Patients With a Tracheostomy Cannula in a Belgium General Hospital: A Retrospective Study.
Patients admitted to intensive care units (ICUs) frequently require prolonged mechanical ventilation. Difficulties in weaning from mechanical ventilation represent an important indication for performing a tracheotomy, which…
- Conditions
- Tracheostomy Patients, Multidisciplinary Care Team, Outcomes, Hospital
- Trial name
- NCT07755969
- Testing
- The implementation of the specialised multidisciplinary tracheostomy team.
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Vitaz
Quality of Life (QOL), Tracheostomy
Feeding Difficulties and Quality of Life in Children With Tracheal Cannula
The over all goal of this observational study is to study if there is an association between the presence of feeding difficulties and self-assessed quality of life in children with tracheal cannula.
- Conditions
- Quality of Life (QOL), Tracheostomy, Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter, Feeding Difficulties
- Trial name
- NCT06893458
- Where
- 2 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Stroke, Acute, TBI
Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy Placement
There is currently no prospective study analyzing the effect of tracheostomy with bedside simultaneous gastrostomy versus tracheostomy with delayed gastrostomy placement (TSG versus TDG) on the outcomes of neurocritically-ill…
- Conditions
- Stroke, Acute, TBI, Neuromuscular Diseases, Status Epilepticus
- Trial name
- BEGASTON (NCT04758052)
- Testing
- Timing of placement
- Where
- United States
- Sponsor
- University of Mississippi Medical Center
Granuloma, Tracheostomy
Treatment of Tracheostomy Granulomas
This study plans to learn more about the different ways used to treat tracheostomy granulomas. Investigators want to see which standard of care method (steroid application, silver nitrate, or betadine) is more successful in…
- Trial name
- NCT02116608
- Testing
- Betadine, Silver Nitrate, Hydrocortisone Butyrate Cream, 1.0%
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Critical Care
Ventilator Tube Holder for Patients With a Tracheostomy
Patients admitted to the critical care unit (CCU) at University Hospital Wales (UHW) have a variety of life-threatening conditions which require specialist care, often including a period of sedation and mechanical ventilation.
- Trial name
- TRACHVest (NCT05281224)
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Cardiff and Vale University Health Board
Respiratory Failure, Speech
Early Speech With One-Way Speaking Valve in Tracheostomy Patients
Patients with tracheostomy who are on and off of mechanical ventilation initially lose the ability to speak, and the use of one-way speaking valves (OWSV) is one method of restoring speech in these patients.
- Conditions
- Respiratory Failure, Speech, Aphonia
- Trial name
- NCT03008174
- Testing
- Early one-way speaking valve (OWSV) assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Deglutition Disorders, Tracheostomy Complication
Deflating the Tracheostomy Tube Cuff and Time for Decannulation
Introduction: Inpatients in an intensive care unit can need tracheostomy. To start the tracheostomy decannulation process, one of the procedures is to deflate the cuff.
- Trial name
- NCT05395728
- Testing
- Deflate the tracheostomy cuff early, Deflate the tracheostomy cuff after complete weaning mechanical ventilation
- Where
- Brazil
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hospital Moinhos de Vento
Other Tracheostomy Complication
Percutaneous Tracheostomy - Systematic Comparison Among Three Methods: Prospective Study
Percutaneous tracheostomy is routinely performed in most intensive care units in the world.Several studies have shown that the procedure is safe and economically efficient in comparison to open surgical operation in the operating…
- Trial name
- NCT01722981
- Testing
- Percutaneous tracheostomy
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Respiratory Failure, Neurological Disease
Procedures, Complications and Follow-up of Tracheostomy in Intensive Care Units.
Tracheostomy is worldwide used for critically ill patients. The aim of our study is to assess the mortality, quality of life, laryngeal function, procedures, early and late complications of tracheostomy performed for critically…
- Conditions
- Respiratory Failure, Neurological Disease, Heart Failure, Airway Management
- Trial name
- NCT01899352
- Testing
- Tracheostomy
- Where
- 11 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- University of Genova
Tracheostomy Decannulation
Effects of Tracheostomy Decannulation on Respiratory Function
This single-center prospective study enrolls adult patients with long-term tracheostomy who are ready for tube removal (decannulation).
- Trial name
- NCT07191509
- Testing
- Speaking Valve ，Tracheostomy Tube Occlusion ，Tracheostomy Tube Ventilation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
Tracheostomy, Oral Cancer
Novel Tracheostomy Tube Fixation Device in Oral Cancer Patients
This study evaluated a novel tracheostomy tube fixation device in post-tracheostomy patients with oral cancer. After tracheostomy, conventional fixation methods may be associated with skin pressure injury, wound contamination…
- Conditions
- Tracheostomy, Oral Cancer, Post-Tracheostomy Care, Tracheostomy Complications
- Trial name
- NCT07701226
- Testing
- Novel Self-Adhesive Bidirectional Tracheostomy Tube Fixation Device, Routine Tracheostomy Care and Conventional Fixation
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine
Tracheostomy, Care Giving Burden
Caregiver Experiences With Tracheostomy
This study aimed to determine the experiences of primary caregivers of patients with tracheostomies on tracheostomy suctioning procedure. This is a semi-structured qualitative study.
- Conditions
- Tracheostomy, Care Giving Burden, Caregiver
- Trial name
- NCT05739578
- Where
- Turkey (Türkiye)
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Uludag University
Tracheostomy
Outcomes After Tracheal Cannula Removal
This longitudinal observational study involves an integrated knowledge translation (IKT) approach involving key stakeholders in the project team to evaluate the tracheostomy management in patients hospitalized in the Swiss…
- Trial name
- Dekan (NCT06047665)
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Katharina Winiker
Tracheostomy
Tracheostomy Robotics and Cutting-edge Health Education for Airway Safety
The goal of this clinical trial is to test the NextGen Tracheostomy Toolkit in people who have a tracheostomy. The main questions it aims to answer are: What is the number of atraumatic tracheostomy suctionings before and after…
- Trial name
- TRACHEAS (NCT06236542)
- Testing
- NextGen automated tracheostomy suctioning device, NextGen mixed-reality tracheostomy tube change system, NextGen Tracheostomy Toolkit
- Where
- 2 sites in United States
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Respiratory Failure, Communication Disorders
Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life
This study evaluates the impact of early tracheostomy speaking valve intervention on communication ability, depression levels, and quality of life in ventilator-dependent patients during the weaning phase.
- Conditions
- Respiratory Failure, Communication Disorders, Depression, Quality of Life
- Trial name
- NCT07005596
- Testing
- Passy-Muir Speaking Valve, Standard Non-Verbal Communication Methods
- Volunteers
- 70 people
- Sponsor
- Far Eastern Memorial Hospital
Traumatic Brain Injury
The Effect of Intermittent Oro-esophageal Tube Feeding on Severe Traumatic Brain Injury Patients With Tracheostomy
This was a multicenter randomized controlled study of 98 severe Traumatic Brain Injury patients with tracheostomy. Patients enrolled were divided randomly into the observation group with Intermittent Oro-esophageal Tube Feeding…
- Trial name
- NCT06248970
- Testing
- Rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Nasogastric tube feeding
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Zeng Changhao
Tracheostomy Techniques
Ultrasound-guided Percutaneous Dilatation Tracheostomy: Does it Have a Role in Obese Patients?
To evaluate the usefulness of ultrasound-guided percutaneous dilatation tracheostomy PCT in obese patients.
- Trial name
- NCT03059654
- Testing
- tracheostomy
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Suez Canal University
Tracheostomy Complication, Post Tracheostomy Complications
Primary vs Secondary Closure of Tracheo-cutaneous Fistulas
The mean of this study is to compare primary and secondary closure of tracheo-cutaneous fistulas and evaluate the differences in outcomes between both techniques.
- Conditions
- Tracheostomy Complication, Post Tracheostomy Complications, Tracheostomy
- Trial name
- TRACH (NCT04647968)
- Testing
- Primary closure of tracheo-cutaneous fistula, Secondary closure of tracheo-cutaneous fistula
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke