Clinical trials: Tracheostomy Weaning
Respiratory Failure, Tracheostomy Complication
Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Lausanne ICU
This retrospective study aims to study characteristics of patients tracheotomized in the Lausanne ICU, both overall and by primary reasons of intubation.
- Trial name
- NCT04987398
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Piquilloud Imboden Lise
Tracheostomized Patients, Mechanical Ventilation Weaning
High Flow Tracheal Oxygen for Weaning of Tracheostomized Patients
In this pilot randomized controlled trial (RCT), the investigators aim to explore the feasibility of conducting a powered RCT that examines the efficacy and safety of high flow tracheal oxygen (HFTO) in weaning critically ill…
- Conditions
- Tracheostomized Patients, Mechanical Ventilation Weaning, High Flow Oxygen Therapy
- Trial name
- HFTO-WEAN (NCT07559591)
- Testing
- High-flow tracheal oxygen (HFTO), Tracheal Mask (TM)
- Where
- Saudi Arabia
- Volunteers
- 88 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Mechanical Ventilation Complication
Mechanical Ventilator Weaning in Chronically Ventilated Patients
Mechanical ventilation is a commonly used life-saving hospital procedure for patients with severe breathing difficulty. Some patients have difficulty separating from the ventilator and need to be removed gradually.
- Trial name
- NCT06976554
- Testing
- weaning
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of California, Los Angeles
Tracheostomy Patients, Tracheostomy Decannulation
Tracheostomy Practice in Adult Intensive Care Units
ON TRACH is an international, multicentre, observational study with the aim of characterising the timing and practice of tracheostomy insertion, management, weaning and longer-term outcomes of these patients, in intensive care…
- Conditions
- Tracheostomy Patients, Tracheostomy Decannulation, Intensive Care (ICU)
- Trial name
- ON TRACH (NCT07769021)
- Where
- 13 sites in United States, Brazil and 6 more
- Volunteers
- 2,500 people
- Sponsor
- Royal College of Surgeons, Ireland
Ischemic Stroke, Intracerebral Hemorrhage
Early Tracheostomy in Ventilated Stroke Patients
Patients with severe ischemic and hemorrhagic strokes, who require mechanical ventilation, have a particularly bad prognosis. If they require long-term ventilation, their orotracheal tube needs to be, like in any other intensive…
- Conditions
- Ischemic Stroke, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- SETPOINT (NCT01261091)
- Testing
- Early Tracheostomy, Late Tracheostomy
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Heidelberg University
Tracheostomy, ICU
Determinants of Successful Decannulation in Difficult-to-wean Patients
The factors of success of decannulation are not well known in the literature and the decision to decannulate is mainly based on clinical judgment.
- Conditions
- Tracheostomy, ICU, Weaning Failure
- Trial name
- DESCATRON (NCT04841889)
- Testing
- Associated factors with decannulation
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Forcilles
Weaning Failure
Changes of Weaning Parameter in Weaning Failure Patient After Tracheostomy as a Predictor of Subsequent Weaning
Weaning from mechanical ventilator is an essential element in the care of critically ill intubated patients receiving mechanical ventilation.
- Trial name
- NCT01312142
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Ventilator Weaning
Early Tracheotomy for Switching Between Invasive and Noninvasive Ventilation to Facilitate Weaning
The aim of this study is early tracheotomy to facilitate weaning by switching between invasive and noninvasive ventilation.
- Trial name
- NCT02921334
- Testing
- switching between invasive and noninvasive ventilation
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chongqing Medical University
ICU Patients, Intubation
Pulmonary and Ventilatory Effects of Trigger Modulation in Intubated ICU
Pressure support ventilation allows intubated ICU patients to breathe spontaneously. Among specific settings, the adjustment of the trigger value (or threshold for triggering the ventilator) has not been explored to date.
- Conditions
- ICU Patients, Intubation, Spontaneously Breathing, Pulmonary Function
- Trial name
- Trigger (NCT04041817)
- Testing
- Trigger setting of pressure support ventilation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Tracheostomy, Cough
Objective Evaluation of Cough Effort in Tracheotomized Patients (LOST Study)
This study aims to evaluate how well tracheotomized patients can cough before and after their tracheostomy tube is removed. Cough strength is measured using two different tools-Peak Flow and Lorio.
- Conditions
- Tracheostomy, Cough, Weaning, Respiratory Function Tests
- Trial name
- NCT07061561
- Testing
- Peak Expiratory Flow Measurement Using Peak Flow Meter and Lorio Device
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Respiratory Failure, Communication Disorders
Early Speaking Valve in Ventilator Weaning: Effects on Communication, Depression, and Quality of Life
This study evaluates the impact of early tracheostomy speaking valve intervention on communication ability, depression levels, and quality of life in ventilator-dependent patients during the weaning phase.
- Conditions
- Respiratory Failure, Communication Disorders, Depression, Quality of Life
- Trial name
- NCT07005596
- Testing
- Passy-Muir Speaking Valve, Standard Non-Verbal Communication Methods
- Volunteers
- 70 people
- Sponsor
- Far Eastern Memorial Hospital
Tracheotomy
Tracheostomy and Weaning From Mechanical Ventilation : Evaluation of the Lung Ultrasound Score
Prospective, interventional multicentric study in ICU during weaning from mechanical ventilation in tracheotomized patients
- Trial name
- TRAWELUS (NCT01793363)
- Testing
- Tracheotomy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Clermont-Ferrand
Mechanical Ventilator Weaning
Assessment of Cough Strength in Patients With Tracheostomies
The investigators propose to assess cough strength in patients undergoing spontaneous breathing trials in the Intermediate Intensive Care Unit (IICU) and compare their cough strength under two conditions, 1.
- Trial name
- NCT02566512
- Testing
- Tracheostomy cuff inflation., Tracheostomy cuff deflation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Deglutition Disorders, Tracheostomy Complication
Deflating the Tracheostomy Tube Cuff and Time for Decannulation
Introduction: Inpatients in an intensive care unit can need tracheostomy. To start the tracheostomy decannulation process, one of the procedures is to deflate the cuff.
- Trial name
- NCT05395728
- Testing
- Deflate the tracheostomy cuff early, Deflate the tracheostomy cuff after complete weaning mechanical ventilation
- Where
- Brazil
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hospital Moinhos de Vento
Patients With Prolonged Weaning
Effects of Nasal Airflow on Sleep in Tracheotomized Patients
The passage of air through the nasal cavities generates rhythmic oscillations transmitted by the olfactory bulb to the brain, which induces cerebral activation in functional brain areas and is associated with better cognitive…
- Trial name
- Nasa (NCT06547463)
- Testing
- nasal oxygenation device
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Difficult to Wean, Mechanically Ventilated Patients With a Tracheostomy
Identifying the Optimal IMT Dose in ICU
200,000 adults are admitted to intensive care in the UK each year. Many of these patients need help with their breathing and are put on a machine called a ventilator.
- Trial name
- NCT07256821
- Testing
- Inspiratory Muscle Training
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Respiratory Distress Syndrome (RDS), Respiratory Ilness
Study on the Correlation Between Tracheotomy Tip Pressure and Esophageal Pressure in Patients Weaned from Tracheotomy
Whether the correlation between gas incision tip pressure fluctuations (ΔPtt) and esophageal pressure fluctuations (ΔPes) is a potential measure of spontaneous respiratory effort in patients undergoing gas incision offline.
- Trial name
- NCT06783777
- Testing
- Esophageal pressure monitoring, Tracheotomy tip pressure
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Shanghai Zhongshan Hospital
Mechanical Ventilation Complication
Effect of Three Modalities of Spontaneous Breathing Tests on Respiratory Efforts in Tracheostomized Patients
Datas are lacking concerning weaning from mechanical ventilation for tracheostomized patients. In particular, the effect of different modalities of spontaneous breathing trials on respiratory effort has not been extensively…
- Trial name
- TWEEP (NCT03856424)
- Testing
- Modality 1, Modality 2, Modality 3
- Where
- Switzerland
- Volunteers
- 18 people
- Sponsor
- Piquilloud Imboden Lise
Invasive Mechanical Ventilation, Critical Illness
Mechanical Ventilation Discontinuation Practices
Background: The requirement for ventilator support is a defining feature of critical illness. Weaning is the process during which the work of breathing is transferred from the ventilator back to the patient.
- Conditions
- Invasive Mechanical Ventilation, Critical Illness, Spontaneous Breathing Trial, Weaning Invasive Mechanical Ventilation
- Trial name
- IOS (NCT03955874)
- Where
- 14 sites in United States, Canada
- Volunteers
- 1,868 people
- Sponsor
- Unity Health Toronto
ARDS
Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation
This study intends to compare the effects of NAVA and PSV on weaning success rate and mechanical ventilation time in patients with tracheotomy patients through a randomized controlled study.
- Trial name
- NCT05219643
- Testing
- NAVA, PSV
- Where
- 2 sites in China
- Volunteers
- 130 people
- Sponsor
- Southeast University, China