Clinical trials: Tramadol Adverse Effect
Trauma, Opioid Analgesic Adverse Reaction
Role of Prophylactic Metoclopramide With Tramadol in Trauma Patients
Tramadol is widely used as analgesic in trauma patients. However, it causes side effects, most notably nausea and vomiting. This study aim to determine the role of prophylactic metoclopramide in preventing tramadol induced nausea…
- Trial name
- NCT03383315
- Testing
- Tramadol, Metoclopramide
- Where
- Malaysia
- Volunteers
- 191 people
- Sponsor
- University of Malaya
Pain, Neonatal Infections
Tramadol Versus Fentanyl for Post-Operative Analgesia in Newborn Infants
In newborn infants submitted to surgical procedures, tramadol may provide an effective analgesia and decrease the time on mechanical ventilation support and the time to achieve full enteral feeding.
- Conditions
- Pain, Neonatal Infections, Analgesia
- Trial name
- NCT00713726
- Testing
- FentanyL, Tramadol
- Where
- Brazil
- Volunteers
- 160 people
- Sponsor
- Federal University of São Paulo
Pain Management, Birth
Combined Intravenous Tramadol and Paracetamol Versus Intramuscular Pethidine for Pain Relief During the First Stage of Labor. Compare the Efficacy and Adverse Effects
The goal of this intervention study is to compare the efficacy and adverse effects of pain relief during the first stage of labor using 75 mg IM pethidine versus the combination of IV 100 mg tramadol and 1000 mg paracetamol.
- Trial name
- NCT07264309
- Testing
- pethidine, Tramadol, Paracetamol 1 g
- Where
- Israel
- Volunteers
- 140 people
- Sponsor
- Zohar Nachum
Adverse Drug Events, Adverse Drug Reactions
YouScript IMPACT Registry
This multicenter observational study aims to investigate the benefits of providing pharmacogenetic testing with the YouScript Personalized Prescribing System which includes a clinical decision support tool and individualized…
- Conditions
- Adverse Drug Events, Adverse Drug Reactions, Drug Interaction Potentiation, Drug Metabolism, Poor, CYP2D6-RELATED
- Trial name
- IMPACT (NCT02191358)
- Where
- 7 sites in United States
- Volunteers
- 800 people
- Sponsor
- Genelex Corporation
Acute Postoperative Pain, Tramadol Adverse Effect
Prospective Pharmacogenetic Cohort Study of CYP2D6 Metabolizer Phenotype, Analgesic Failure, and Adverse Effects in Postoperative Patients Receiving Tramadol by Elastomeric Infusion Pump
This prospective pharmacogenetic cohort will enroll postoperative patients receiving a standardized tramadol-containing elastomeric analgesia pump.
- Conditions
- Acute Postoperative Pain, Tramadol Adverse Effect, Pharmacogenetic Variation
- Trial name
- NCT07810816
- Testing
- Standardized Tramadol Elastomeric Analgesia Pump, CYP2D6 Genotyping and Metabolizer Phenotype Assignment
- Where
- Colombia
- Volunteers
- 200 people
- Sponsor
- Research Inc
Ambulatory Surgery
Tramadol iv. : Influence of Dose and Dose Intervals on Therapeutic Accuracy and Side Effects When Used for Postoperative Pain Relief in Ambulatory Surgery
The aim of this study is to compare the administration of 1 unit dose of 100 mg tramadol intravenously versus multiple smaller dosages of tramadol during the first 6 hours post-operatively and to investigate the time course and…
- Trial name
- NCT00333346
- Testing
- Administration of tramadol intravenously
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Ghent
Drug Toxicity, Platelet Dysfunction
The Influence of Tramadol on Platelet Function
The aim of this ex-vivo study is to quantify the effect of tramadol on platelet aggregation.
- Conditions
- Drug Toxicity, Platelet Dysfunction, Clotting Disorder
- Trial name
- NCT05237492
- Testing
- Tramadol
- Where
- Austria
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Pain
Comparison of Tramadol Orally Versus an Optimized Dose of Intravenous Tramadol for Postoperative Pain Relief in Ambulatory Surgery
The purpose of this study is to compare the administration of 1 unit dose of 50 mg tramadol perorally given in 3 unit dosages versus tramadol IV given in 3 unit dosage of 35 mg during the first 6 hours postoperatively and to…
- Trial name
- NCT00735748
- Testing
- Tramadol per os (Tradonal Odis® orodispersible tablets), Tramadol IV (Tradonal® IV)
- Where
- Belgium
- Volunteers
- 195 people
- Sponsor
- University Hospital, Ghent
Hip Fracture, Postoperative Pain
Effect of PENG Block on Postoperative Tramadol Consumption in Partial Hip Prosthesis Surgery
This study aims to evaluate the effect of ultrasound-guided pericapsular nerve group (PENG) block on postoperative tramadol consumption, pain scores, and clinical outcomes in patients undergoing partial hip prosthesis surgery.
- Trial name
- PENG-PKP (NCT07534137)
- Testing
- PENG Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- University of Gaziantep