Clinical trials: Transcranial Alternating Current Stimulations
Consciousness Disorders
Transcranial Alternating Current Stimulation in Patients With Disorders of Consciousness
In recent years, many literatures have reported that tACS, as a non-invasive electrical brain stimulation technique, has been applied in depression, schizophrenia, dementia and other fields.
- Trial name
- NCT06211439
- Testing
- real transcranial alternating current stimulation
- Where
- China
- Volunteers
- 64 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Non-suicidal Self-injury
Effects of taVNS Combined With tACS on Adolescents With Non-Suicidal Self-Injury
NSSI behavior is highly prevalent among adolescents, and its mechanisms are closely associated with attentional bias toward self-injury-related information and impulsivity, both of which may be related to reduced dlPFC activation…
- Trial name
- NCT07486804
- Testing
- 25Hz、300us transcutaneous auricular vagus nerve stimulation and10hz transcranial alternating current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Substance Use Disorders
Non-Invasive Brain Stimulation and Substance Use
The will investigate the feasibility and effectiveness and initial efficacy of non-invasive transcranial alternating current stimulation (tACS) on distress tolerance and inhibitory control among treatment seeking substance users.
- Trial name
- NCT03122587
- Testing
- Transcranial Alternating Current Stimulation at 10 Hz, Transcranial Alternating Current Stimulation at 40 Hz
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of North Carolina, Chapel Hill
Treatment Resistant Depression (TRD), Inflammation
TACS on High-inflammatory and Refractory Depression
This study is a randomized controlled trial with a duration of 12 weeks (4 weeks of intervention + 8 weeks of follow-up). The participants are patients with treatment-resistant depression (TRD) and high inflammatory activity…
- Trial name
- NCT06812923
- Testing
- transcranial Alternating Current Stimulation (tACS)
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tianjin Anding Hospital
Postoperative Anxiety in Patients Undergoing Intraspinal Tumor Resection
Effects of Transcranial Alternating Current Stimulation on Postoperative Anxiety in Patients Undergoing Intraspinal Tumor Resection
The incidence of postoperative anxiety in surgery ranges from 4.1% to 79.6% , and among patients undergoing intraspinal tumor resection surgery, the incidence of postoperative anxiety is as high as 46.7%.Adverse effects induced…
- Trial name
- NCT07713368
- Testing
- Transcranial Alternating Current Stimulation
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Xuanwu Hospital, Beijing
Systemic Lupus Erythematosus, Depression
LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE
The purpose of this study is to investigate the effects of a type of non-invasive transcranial alternating current stimulation (tACS) on patients diagnosed with systemic lupus erythematosus (SLE) who are experiencing depression.
- Trial name
- NCT04141046
- Testing
- XCSITE100 Stimulator - Individualized theta-tACS, XCSITE100 Stimulator - Individualized alpha-tACS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of North Carolina, Chapel Hill
Stroke
Transcranial Alternating Current Stimulation (tACS) to Improve Motor Skill Acquisition in Stroke Patients
Hand motor function is often severely affected in stroke patients and its recovery is one primary goal in stroke rehabilitative treatment programs.
- Trial name
- NCT05576129
- Testing
- TGP-tACS
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Substance Dependence, Executive Function Disorder
Brain Mechanism and Intervention of Executive-control Dysfunction Among Substance Dependents
The investigators assume that tACS could improve amphetamine and alcohol dependent patients' executive-control function by adjusting the synchronization patterns and enhancing the functional connectivity of the prefrontal-ventral…
- Conditions
- Substance Dependence, Executive Function Disorder, Transcranial Alternating Current Stimulation
- Trial name
- NCT05312359
- Testing
- Transcranial alternating current stimulation-true stimulus
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Parkinson Disease, Pain
Transcranial Alternating Current for Oscillopathies
The need for non-invasive, non-pharmacological and cost-effective therapeutic options has revived the use of transcranial current stimulation, either direct (tDCS) or alternating (tACS), in a wide range of pathologies and…
- Trial name
- tACS_EEG (NCT03221413)
- Testing
- transcranial alternating current stimulation (tACS)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Padova
Stroke, Aphasia
Transcranial Alternating Current Stimulation in Post Stroke Aphasia Therapy
This study aims to investigate the efficacy of transcranial alternating current stimulation (tACS) combined with linguistic training for patients with chronic post-stroke aphasia.
- Trial name
- AfatES (NCT07510464)
- Testing
- active 75 Hz transcranial alternating current stimulation
- Where
- Poland
- Volunteers
- 11 people
- Sponsor
- QVITI S.A.
Pain
Spatiotemporal Thalamocortical Alterations Underlie Experimental and Chronic Pain
The purpose of this study is to assess thalamocortical (TC) connectivity during tonic pressure pain, to evaluate alpha activity during tonic pressure pain and to determine pressure pain ratings by using Electroencephalography…
- Trial name
- NCT06968689
- Testing
- transcranial alternating current stimulation (tACS), transcranial random noise stimulation (tRNS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Parkinson Disease
tACS Modulates Speech and Cognitive Impairments in People With PD by Targeting the Medial Frontal Cortex
This clinical trial aims to study whether transcranial alternating current stimulation (tACS) applied to the medial frontal cortex (MFC) can improve speech and cognitive function in people with Parkinson's disease (PD), and to…
- Trial name
- NCT07240272
- Testing
- 6Hz-tACS
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ke Dong, MD
Parkinson Disease
Investigation of the Benefits of Electrical Non-invasive Stimulation on Cognitive Symptoms in Parkinson's Disease
Parkinson's disease is the second most common neurodegenerative disease after Alzheimer's disease. It is mostly characterized by the presence of motor difficulties.
- Trial name
- STIMPARK (NCT05808504)
- Testing
- Neuropsychological assessment, Neurological assessment, Cognitive task
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Antenatal Depression, Major Depressive Disorder
Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)
The purpose of this study is to develop the safety, feasibility, and tolerability of a personalized transcranial alternating current stimulation (tACS) approach in antenatal depression.
- Conditions
- Antenatal Depression, Major Depressive Disorder, Major Depressive Disorder in Pregnancy, Healthy Controls
- Trial name
- PandA-tACS (NCT06979154)
- Testing
- tACS (aperiodic)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Pain
A Study on the Efficacy of Dual-Carrier-Frequency Transcranial Alternating Current Stimulation Modulating the Hippocampus for the Treatment of Chronic Non-Specific Low Back Pain
This is a single-center, randomized, double-blind, sham-controlled trial evaluating dual-carrier-frequency transcranial alternating current stimulation targeting the hippocampus in 60 patients with chronic non-specific low back…
- Trial name
- NCT07832188
- Testing
- Dual-carrier-frequency transcranial alternating current stimulation, Transcranial electrical stimulation (tES)
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Qilu Hospital of Shandong University
Seizures
Boosting The Intervention Effect of Negative Memory Through tACS Stimulation
The objectives of this study include: 1) investigating the impact of negative memory substitution on an individual's other intellectual memories (i.e., neutral memories) and the underlying neurocognitive mechanisms; 2)…
- Trial name
- NCT06375395
- Testing
- Active tACS Device
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing
Antenatal Depression
Single Session Personalized Aperiodic Transcranial Alternating Current Stimulation (PandA-tACS) for Antenatal Depression
The purpose of this pilot trial is to primarily assess safety, feasibility, and tolerability of PandA-tACS in antenatal depression and determine whether a single PandA-tACS session produces greater left dlPFC aperiodic slope…
- Trial name
- PandA (NCT07799480)
- Testing
- IAF-tACS, PandA-tACS
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Chapel Hill
Mild Cognitive Impairment (MCI)
TACS to Engage Theta-Gamma Coupling and Enhance Working Memory in Patients With MCI (tACS-MCI)
This study is looking at a new non-invasive brain stimulation methods called transcranial alternating current stimulation (tACS) to see if it can improve working memory and thinking processes in people with Mild Cognitive…
- Trial name
- tACS-MCI (NCT06783283)
- Testing
- Transcranial Alternating Current Stimulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Addiction and Mental Health
Healthy
Effects of Alpha tACS
**Follow-up Control Study for Creativity Study Purpose: To investigate the effect of transcranial alternating current stimulation (tACS), a form of noninvasive brain stimulation, in healthy subjects.
- Trial name
- PACS (NCT03135639)
- Testing
- NeuroConn Plus Stimulator tACS
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Schizophrenia, Schizoaffective Disorder
Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation Applied Pre-cognitive Behavioral Therapy for Psychosis) Associated to Usual Medication Regimen
The investigators are proposing a new, non-invasive therapeutic model using transcranial alternative current stimulation (tACS), to augment cognitive behavioral therapy for psychosis (CBTp) efficacy in individuals with…
- Trial name
- tACS/CBTpSZ (NCT06889025)
- Testing
- Experimental: tASC/CBTp: gamma band electric stimulation for 20 minutes at the beginning of the CBTp session
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Felicia Iftene