Clinical trials: Transcranial Doppler Ultrasound
Cardiovascular, Diabetes
Home-Based Walking Study in Older Adults With Type 2 Diabetes
Older persons with diabetes have a harder time maintaining blood pressure when standing up. When blood pressure drops when standing up, fainting may occur.
- Conditions
- Cardiovascular, Diabetes, Orthostatic Hypotension, Type 2 Diabetes
- Trial name
- NCT00824330
- Testing
- Control Phase; Exercise Phase
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of British Columbia
Trauma, Brain
Transcranial Doppler in Mild and Moderate Traumatic Brain Injury (TBI)
Utility of transcranial Doppler as an Early Predictor of Neurological deterioration in Mild and Moderate Traumatic Brain Injury
- Trial name
- NCT05151978
- Testing
- Transcranial Doppler
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Propofol-anaesthesia Via Target-controlled Infusion
The Effect of Different End-tidal Carbon-dioxide Levels on Cerebral CO2 Vasoreactivity and the Stiffness of Systemic Arteries During Propofol Anesthesia
Purpose: The purpose of this study is to examine the effect of different carbon-dioxide concentrations on cerebral CO2 sensitivity and the resistance and stiffness of systemic arteries during anesthesia with target-controlled…
- Trial name
- NCT02203097
- Testing
- Partial pressure of CO2 at the end of an exhaled breath, Propofol
- Where
- Hungary
- Volunteers
- 25 people
- Sponsor
- University of Debrecen
Stroke, Intracerebral Hemorrhage
AI-assisted Transcranial Duplex Sonography for Early Detection of Intracerebral Haemorrhage: HYPER-AI-SCAN
The goal of this observational study is to evaluate whether transcranial Doppler ultrasound, combined with artificial intelligence (AI), can help identify intracerebral haemorrhage (ICH) in people with acute stroke (both men and…
- Conditions
- Stroke, Intracerebral Hemorrhage, Intracerebral Hemorrhage Basal Ganglia, Intracerebral Haemorrhage
- Trial name
- NCT07319013
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Coronary Artery Disease
Sonolysis in Risk Reduction of Symptomatic and Silent Brain Infarctions During Coronary Stenting
The aim of the project is to demonstrate a fibrinolytic effect of sonothrombolysis (continual transcranial Doppler monitoring) using 2 MHz diagnostic probe on the reduction of risk of brain infarctions due to the activation of…
- Trial name
- NCT02351050
- Testing
- Sonolysis
- Where
- Slovakia
- Volunteers
- 144 people
- Sponsor
- University Hospital Ostrava
Stroke, Cancer
Mechanisms of Ischemic Stroke in Cancer Patients
The purpose of this study is to better understand the causes of stroke in people with cancer. Active cancer increases the risk of stroke.
- Trial name
- MOST-CA (NCT02604667)
- Testing
- Blood tests, Transcranial Doppler Microemboli Detection Study
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Weill Medical College of Cornell University
Neurological Complication
Transcranial Doppler, Optic Nerve Envelope Diameter and Quantitative Pupillometry Measurements
Non-invasive neuromonitoring tools such as transcranial doppler, optic nerve envelope diameter measurement and quantitative pupillometry are routinely used in acute brain injured patients as part of multimodal neuromonitoring…
- Trial name
- DOPPLER (NCT05843214)
- Testing
- Non-invasive neuromonitoring evaluation (transcranial doppler, optic nerve envelope diameter and quantitative pupillometry)
- Where
- Reunion
- Volunteers
- 230 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Intracranial Aneurysm, Aneurysm, Intracranial
Transcranial Doppler Ultrasound Monitoring During Flow-Diverter Embolization
Flow diverters have been approved since 2012 for the treatment of large, wide neck intracranial aneurysms. These devices have been associated with embolic events which cause blockage in a blood vessel and can result in long term…
- Conditions
- Intracranial Aneurysm, Aneurysm, Intracranial, Giant Intracranial Aneurysm
- Trial name
- NCT02354300
- Testing
- TCD Ultrasound
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Vertebrobasilar Insufficiency
Clinical and Radiological Evaluation of Patients With Vertebrobasilar Insufficiency in Assiut University Hospital
Clinical and radiological evaluation including transcranial Doppler of vertebral arteries of patients with vertebrobasilar insufficiency attending assiut university hospital and assessment of possible risk factors that may lead…
- Trial name
- NCT05019391
- Testing
- transcranial doppler
- Volunteers
- 100 people
- Sponsor
- Assiut University
Trancranial Doppler
Transcranial Ultrasound and Transcranial Doppler in Diagnosis and Detection of Outcome in Infants With Neurological Diseases
To evaluate the accuracy of transcranial ultrasound in detection of brain pathology in infants with neurological diseases and value of transcranial Doppler in evaluation of intracerebral blood flow in comparison with other…
- Trial name
- NCT06352931
- Testing
- transcranial and transcranial dopp;er
- Volunteers
- 50 people
- Sponsor
- Assiut University
Obesity, Cerebrovascular Function
Respiratory Muscle Training to Improve Cerebrovascular and Immune Function
Millions of adults in America have too much body fat, resulting in obesity. Obesity is detrimental to health and causes disease. Obesity reduces brain health, which causes the brain to function less effectively.
- Conditions
- Obesity, Cerebrovascular Function, Immune Cells Activity
- Trial name
- NCT07406295
- Testing
- High intensity inspiratory muscle strength training, Low intensity
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Florida State University
Subarachnoid Hemorrhage, Vasospasm, Intracranial
Prolonged Vasospasm in Subarachnoid Hemorrhage
The prevalence and clinical implications of prolonged cerebral vasospasm in patients with subarachnoid hemorrhage are unknown.
- Trial name
- PVE (NCT04193124)
- Testing
- transcranial doppler.
- Volunteers
- 109 people
- Sponsor
- Hospital El Cruce
Intensive Care Unit Syndrome
Cerebral Perfusion Variation During Blood Pressure Changes in ICU
The risk associated with arterial hypotension during anesthesia for intensive care sedation has been demonstrated, but the threshold at which consequences for perfusion of one or more organs appear varies according to the…
- Trial name
- DELTAPAMREA (NCT05804773)
- Testing
- Non-invasive Measurement of cerebral blood velocity in the middle cerebral artery by transcranial pulsed Doppler (TCD) (Mean velocity, Vm, cm/s)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Insufficiency
Influence Positive End-expiratory Pressure on Autoregulation in Patients With Respiratory Insufficiency
The aim of the present study is to characterize the influence of an elevated positive end-expiratory pressure in patients with acute respiratory distress syndrome or acute lung injury on the cerebrovascular autoregulation.
- Trial name
- dARICUPEEP (NCT01376518)
- Testing
- positive end-expiratory pressure
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Johannes Gutenberg University Mainz
Sickle Cell Anemia, Sickle Cell Disease
Sickle Cell Disease - Stroke Prevention in Nigeria Trial
Given large absolute numbers of individuals with sickle cell disease in Nigeria, hydroxyurea therapy for all individuals with sickle cell disease may not be initially feasible; however, a targeted strategy of hydroxyurea use for…
- Conditions
- Sickle Cell Anemia, Sickle Cell Disease, Stroke
- Trial name
- SPIN (NCT01801423)
- Testing
- Hydroxyurea
- Where
- Nigeria
- Volunteers
- 29 people
- Sponsor
- Vanderbilt University Medical Center
Neuro-intensive Care Unit Patients, Brain Injuries
Third Ventricle Echographic Study for Neuro-intensive Care Unit Patients
Transcranial Doppler ultrasonography is usually used in the evaluation and management of patients with brain injury. This noninvasive method measures local blood flow velocity and direction in the proximal portions of large…
- Trial name
- ECHO-V3 (NCT02830269)
- Testing
- Transcranial Doppler ultrasonography measurements
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Sickle Cell Disease
Measurement of Cerebral Blood Flow Using Transcranial Doppler Ultrasound in Children With Sickle Cell Disease
Sickle cell disease (SCD) affects haemoglobin - the molecule in blood cells which carries oxygen. It causes red blood cells to become abnormal crescent (or sickle)- shaped.
- Trial name
- NCT02090881
- Testing
- Ultrasound scan
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Imperial College Healthcare NHS Trust
Cerebrovascular Circulation
NIRS vs TCD for Cerebrovascular Autoregulation During Non-cardiac Surgery
Postoperative neurocognitive disorders (NCD) are of high priority in perioperative management. The risk of suffering from NCD after surgery may be increased due to perioperative impairment of cerebrovascular autoregulation and…
- Trial name
- SONICA (NCT04978558)
- Testing
- Continuous assessment of cerebrovascular autoregulation with NIRS and TCD
- Where
- Germany
- Volunteers
- 509 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf