Clinical trials: Transdiagnostic
Emotional Disorder, Depression, Anxiety
Study on the Effectiveness and Differential Usability of the UP in Spanish University Students
The present study seeks to compare and analyze the degree of usefulness, acceptability and implementation of the Unified Protocol (UP) in its application in two cost-effective formats, the online group and the blended online…
- Conditions
- Emotional Disorder, Depression, Anxiety, Emotion Regulation
- Trial name
- NCT06432829
- Testing
- Unified Protocol for the transdiagnostic treatment of emotional disorders
- Where
- Spain
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Emotional Disorder, Anxiety
Builders of Emotional Regulation: Acceptability, Feasibility, and Effectiveness of the Group Unified Protocol for Treating Emotional Disorders in Online and In-Person Modalities
The Unified Protocol (UP) is a transdiagnostic, emotion-focused, cognitive-behavioral intervention developed to treat emotional disorders.
- Conditions
- Emotional Disorder, Anxiety, Depression
- Trial name
- NCT07715604
- Testing
- Unified Protocol
- Where
- Portugal
- Volunteers
- 54 people
- Sponsor
- University of Coimbra
Mental Health Issue
UNIPDES- An Internet-Based Transdiagnostic Intervention for College Students' Psychological Symptoms
This study is a randomised clinical trial. This study evaluates the effect of an internet-based intervention developed based on a transdiagnostic cognitive behavioural approach on psychological symptoms of university students.
- Trial name
- UNIPDES (NCT06245200)
- Testing
- UNIPDES - Internet Based Intervention - GUIDED, UNIPDES - Internet Based Intervention - UNGUIDED
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Anadolu University
Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD)
Transdiagnostic Metacognitive Therapy Compared to Disorder-Specific Cognitive-Behavioral Therapy for Anxiety Disorders
Background Anxiety disorders are the most prevalent psychiatric disorders around the world. Effective treatment consists of pharmacotherapy or psychological treatment based on cognitive-behavioral therapy (CBT) and these…
- Conditions
- Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT06937892
- Testing
- Transdiagnostic metacognitive therapy, Disorder-specific cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 86 people
- Sponsor
- Karolinska Institutet
OCD, Major Depressive Disorder (MDD)
Computer Game, Qualitative, and MEG/EEG Assessment of Serotonergic Psychedelics
This is an observational study which does NOT directly administer a psychedelic substance but rather recruits participants who are already participating in another clinical trial in which they may receive a serotonergic…
- Conditions
- OCD, Major Depressive Disorder (MDD), Alcohol Use Disorder (AUD), Healthy Volunteer
- Trial name
- NCT06624137
- Testing
- Serotonergic Psychedelic
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Yale University
Sleep, Autism Spectrum Disorder
Transdiagnostic Sleep and Circadian Treatment for Autistic Adults
Sleep and circadian problems are associated with deleterious social, emotional, and cognitive outcomes, yet are modifiable. This prospective study will adapt and optimize an empirically supported behavioral intervention that…
- Conditions
- Sleep, Autism Spectrum Disorder, Transdiagnostic
- Trial name
- NCT07461844
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction
- Volunteers
- 24 people
- Sponsor
- Milton S. Hershey Medical Center
Sleep Disorders, Circadian Rhythm, Sleep Disorder
Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment
The goal is to collect pilot data on an adapted version of the Transdiagnostic Sleep and Circadian intervention (TranS-C), referred to as 'Fitted TranS-C'.
- Conditions
- Sleep Disorders, Circadian Rhythm, Sleep Disorder, Acceptability, Feasibility
- Trial name
- NCT03556878
- Testing
- Fitted Transdiagnostic Sleep and Circadian intervention
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, Berkeley
Depression, Anxiety, Alcohol Abuse
Cognitive-Behavioral Therapy for Young Adult Lesbian, Gay and Bisexual: Transdiagnostic Minority Stress Approach
Background: LGB people experience a large number of anxiety and mood disorders, and risk behaviors than heterosexual (Marshall et al., 2011).
- Conditions
- Depression, Anxiety, Alcohol Abuse, Sexual Compulsivity, Unsafe Sex
- Trial name
- NCT03980873
- Testing
- ESTEEM (Effective Sikills to Empower Effective Men)
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Psychological Disorder
Transdiagnostic Internet Intervention to Improve Mental Health Among University Students
This study offers transdiagnostic CBT-based treatment for symptoms of depression and anxiety to university students who have previously responded to the WHO-WMH-ICS survey.
- Trial name
- NCT05085756
- Testing
- Puma
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Uppsala University
Depression, Anxiety
Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression
Depression and anxiety are the most prevalent mental disorders among both the general population and young adults, and transdiagnostic treatments for these patients are mostly based on cognitive-behavioral therapy (CBT).
- Trial name
- IBTTYOUNG (NCT06384196)
- Testing
- Identity-Based Transdiagnostic Therapy (IBTT), Unified Protocol
- Where
- 2 sites in Spain
- Volunteers
- 138 people
- Sponsor
- University of Barcelona
Antenatal Depression, Antenatal Anxiety
Effectiveness and Cost-effectiveness of Simultaneous Screening and Intervention for Antenatal Depression and Anxiety Symptoms From a Transdiagnostic Perspective: A Scale-up Feasibility Study
This scale-up study aimed to explore the effectiveness of simultaneous screening and intervention of antenatal depression and anxiety in preventing postpartum depression and anxiety and how scale-up might be successfully…
- Trial name
- NCT07349368
- Testing
- implementation group
- Where
- China
- Volunteers
- 3,314 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Generalized Anxiety Disorder
A Feasibility Study of Group Metacognitive Therapy Versus Mindfulness Meditation Therapy
The study will examine the effectiveness of group metacognitive therapy in comparison with group meditation therapy, in patients with Generalised Anxiety Disorder.
- Trial name
- MCT (NCT02096484)
- Testing
- Group Metacognitive Therapy, Mindfulness Meditation Therapy
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Manchester
Mental Disorders
Text Message Based Maintenance Intervention
The study presents findings from a randomized clinical trial evaluating the effects of text messages encouraging short emotion regulation exercises on the course of psychopathological symptoms after inpatient treatment for…
- Trial name
- NCT02529358
- Testing
- standardized text messages, Personalized text messages, Standardized text messages after 10 weeks
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Friedrich-Alexander-Universität Erlangen-Nürnberg
Healthy Participants Study
ACT-based EMI in College Students
This study aims to evaluate the acceptability and effectiveness of a transdiagnostic, Acceptance and Commitment Therapy (ACT)-based ecological momentary intervention (EMI) among college students.
- Trial name
- NCT06843395
- Testing
- ACT-based ecological momentary intervention, Mood monitoring
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Smoking, Anxiety Disorders
Smoking Termination / Anxiety Reduction Treatment (ST/ART)
The primary aim of this research study is to enhance smoking cessation outcome among smokers with anxiety disorders. The investigators are comparing two group treatment approaches: (1) An educational-supportive psychotherapy and…
- Trial name
- START (NCT01789125)
- Testing
- Nicotine Patch, Smoking Termination and Anxiety Reduction Treatment, Education-Supportive Psychotherapy
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of Houston
Mental Disorder
Acute-REMOTION: REMOTION in Acute Psychiatric Care
This study aims to examine REMOTION, an internet-based intervention aimed at reducing symptom severity and improving emotion regulation in an acute psychiatric inpatient care setting.
- Trial name
- Acute-REMOTION (NCT04990674)
- Testing
- REMOTION, TAU
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Bern
Anxiety Disorders, Depression
Development of Transdiagnostic Single-session Treatment
The goal of this clinical trial is to test a single session treatment program in primary care patients with anxiety and/or depression and/or stress-related issues.
- Conditions
- Anxiety Disorders, Depression, Stress Disorder
- Trial name
- NCT05784259
- Testing
- Transdiagnostic single-session treatment
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Luleå Tekniska Universitet
Substance Use Disorders, Depression
Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
The overall aim of this pilot study is to conduct a preliminary trial to evaluate the acceptability and feasibility of adding a transdiagnostic, emotion-focused group intervention (the Unified Protocol, UP) to treatment as usual…
- Conditions
- Substance Use Disorders, Depression, Anxiety, Emotional Disorder
- Trial name
- ARMS UP (NCT03315208)
- Testing
- Unified Protocol (UP), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Sexual Distress, Sexual Dysfunctions
Anthesis: A Transdiagnostic Cognitive-Behavioral Therapy (CBT)-Based Approach to Sexual Distress: Testing a Pilot Online Intervention
This pilot study, named Anthesis, evaluates the preliminary efficacy of an online pilot study for sexual distress related to sexual function (SDRSF) in adults.
- Trial name
- Anthesis (NCT06823973)
- Testing
- CBT-based transdiagnostic approach to sexual distress, Waiting list condition
- Where
- 2 sites in Portugal
- Volunteers
- 30 people
- Sponsor
- Grupo Lusófona
Emotion Regulation, Anxiety Disorders
Efficacy of a Web-Based Emotion Regulation Training in a Transdiagnostic Sample
This two-armed randomized controlled trial investigates the efficacy of a web-based emotion regulation intervention in a transdiagnostic sample.
- Conditions
- Emotion Regulation, Anxiety Disorders, Depression, Eating Disorders
- Trial name
- NCT06183333
- Testing
- Heidelberg Emotion Regulation Training
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Heidelberg University