Clinical trials: Transdiagnostic
Emotional Disorder
Clinical Effectiveness of the MultiCentre Pain Monitor to Guide and Personalize Psychological Treatments: A Single Case Design
The present project aims at testing the clinical effectiveness of an app-based system called Multicentre Pain Monitor for routine outcome monitoring of adult patients with emotional disorders while they are administered a…
- Trial name
- NCT05098288
- Testing
- Multicentre Pain Monitor + Unified Protocol
- Volunteers
- 30 people
- Sponsor
- Universitat Jaume I
Non-suicidal Self-injury (NSSI)
Blended Unified Protocol in Chinese Adolescents With Non-Suicidal Self-Injury
This study utilizes the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Adolescents (UP-A) to address non-suicidal self-injury among Chinese adolescents.
- Trial name
- NCT06858540
- Testing
- Unified protocol for transdiagnostic treatment of emotional disorders in adolescents
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Jian-Jun Ou
Anxiety Disorder, Depressive Disorder
Internet Transdiagnostic-CBT for Anxiety and Depression in Adolescents
This study represents the first research program to assess the efficacy of transdiagnostic cognitive behavior therapy (T-CBT) delivered via internet for anxiety and depression in adolescents.
- Conditions
- Anxiety Disorder, Depressive Disorder, Emotional Disorder
- Trial name
- NCT04182061
- Testing
- The AMTE protocol
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad Nacional de Educación a Distancia
Psychological Adjustment, Compassion
Rebalance: Compassion Focused Therapy in a Transdiagnostic Health Group
This study evaluates the use of group Compassion Focussed Therapy in a population with various and/or multiple long term health conditions.
- Conditions
- Psychological Adjustment, Compassion, Chronic Disease
- Trial name
- NCT04040972
- Testing
- Compassion Focussed Therapy
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Edinburgh
Depression, Anxiety
Community Health Worker Implementation of Transdiagnostic Evidence-based Mental Health Intervention for Spanish-speaking Latine Parents
The goal of this clinical trial is to learn if it is doable for community health workers (CHWs) to deliver a mental health intervention to Spanish-speaking Latine parents experiencing anxiety, depression, and/or traumatic stress.
- Conditions
- Depression, Anxiety, Traumatic Stress
- Trial name
- NCT07390630
- Testing
- Common Elements Treatment Approach (CETA)
- Volunteers
- 52 people
- Sponsor
- University of Illinois at Chicago
Duchenne Muscular Dystrophy
Sleep Intervention in Young Boys with Duchenne Muscular Dystrophy
This project will systematically plan and evaluate the implementation of the Transdiagnostic Sleep and Circadian Intervention for youth (TranS-CY).
- Trial name
- DMD (NCT04529707)
- Testing
- Transdiagnostic Behavioral Sleep Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Pittsburgh
Anxiety Disorders
Reducing Mental Health Disparities Among Latinxs With a Telenovela Intervention
The primary aim of our study is to determine the effectiveness of an transdiagnostic telenovela video intervention in reducing anxiety and depressive symptoms using a pre/post-test design with Spanish-speaking Latinxs.
- Trial name
- NCT06163599
- Testing
- Transdiagnostic Telenovela Intervention
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nevada, Reno
Mental Disorder in Adolescence, Insomnia
Promoting Sleep and Physical Activity Among Adolescent Psychiatric Patients
Mental health disorders pose a significant burden on adolescent populations globally, often accompanied by sleep disturbances. Emerging evidence suggests that addressing sleep issues can improve mental health outcomes, while…
- Conditions
- Mental Disorder in Adolescence, Insomnia, Delayed Sleep-Wake Phase Disorder
- Trial name
- SLEEPAC (NCT06407258)
- Testing
- SLEEPAC
- Where
- 2 sites in Switzerland
- Volunteers
- 140 people
- Sponsor
- Christin Lang
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response
Many patients with Major Depressive Disorder (MDD) and generalized Social Anxiety Disorder (gSAD) are treated with cognitive behavioral therapy (CBT) but few have meaningful improvement.
- Trial name
- NCT03175068
- Testing
- CBT, ST
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Anxiety
A Pilot RCT on the Efficacy of TranS-C Intervention on Anxiety Symptoms
This study will examine whether the Transdiagnostic Sleep and Circadian Intervention (TranS-C; Harvey \& Buysse, 2017) can improve sleep and circadian functioning and reduce disorder-focused symptoms in patients with anxiety…
- Trial name
- NCT05453981
- Testing
- Transdiagnostic Sleep and Circadian Intervention
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
Mental Health, Mental Disorders
Personalized, Transdiagnostic Approach to Preventative Mental Health
This study is investigating the self-report adherence and assessment completion rates when presented with a transdiagnostic, partial assessment multiple times a day when compared with a monotopic, complete assessment once a day.
- Conditions
- Mental Health, Mental Disorders, Delivery of Health Care, Self-Assessment
- Trial name
- NCT03946319
- Testing
- Introspect Health
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Introspect Health
Insomnia, Delayed Sleep Phase Disorder
Blue-blocking Glasses for Sleep Disorders in Child and Adolescent Psychiatry
Sleep problems and regulation difficulties are frequent in the child and adolescent psychiatry population. Insomnia and delayed sleep-wake phase disorders (DSPWD) are highly prevalent, and risk factors for developing more severe…
- Conditions
- Insomnia, Delayed Sleep Phase Disorder, Hyperarousal, Transdiagnostic Psychopathology
- Trial name
- BATCAT-pilot (NCT07433491)
- Testing
- Blue-blocking glasses (BB-glasses) or real darkness from 9 p.m. to desired wake-up time + night mode setting on mobile phone, Control
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Helse Fonna
Anxiety Disorders, Depressive Disorders
Efficacy of a Transdiagnostic Group Treatment for Emotional Disorders Applied in Blended Format: a Controlled Study.
This study will consist in a randomized controlled clinical trial (RCT) to test the efficacy of a blended group transversal protocol (BLGr-TP) compared to a face-to-face group transversal protocol (FFGr-TP).
- Trial name
- NCT05569018
- Testing
- Blended group transversal protocol (BLGr-TP), Face-to-face group transversal protocol (FFGr-TP)
- Where
- Spain
- Volunteers
- 144 people
- Sponsor
- Universitat Jaume I
Psychiatric Disorders, Depression - Major Depressive Disorder
Implementing Action-Based Cognitive Remediation for Transdiagnostic Cognitive Difficulties in a Tertiary Mental Health Hospital
Psychiatric conditions are each defined by different set of symptoms, however, they often share common characteristics such as impairments in cognitive and social functioning.
- Conditions
- Psychiatric Disorders, Depression - Major Depressive Disorder, Schizophrenia and Other Psychotic Disorders, Anxiety and Mood Disorders
- Trial name
- NCT07506070
- Testing
- Action-Based Cognitive Remediation
- Volunteers
- 160 people
- Sponsor
- The Royal Ottawa Mental Health Centre
Anxiety Disorders, Trauma
Respiratory Training in the Treatment of Transdiagnostic Pathological Anxiety
Purpose of the Research: The primary aim of the proposed study is to conduct a randomized parallel-group 2-arm clinical trial investigating capnometry-guided respiratory intervention (CGRI) for pathological anxiety.
- Conditions
- Anxiety Disorders, Trauma, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT05427708
- Testing
- Capnometry-Guided Respiratory Intervention, Psycho-Education
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Texas at Austin
Emotional Disorders, Anxiety
Unified Protocol Group Treatment in a University Outpatient Clinic
This clinical trial aims to evaluate the effectiveness and underlying processes of change of the Unified Protocol (UP) for treating emotional disorders in a university outpatient clinic.
- Conditions
- Emotional Disorders, Anxiety, Depression - Major Depressive Disorder
- Trial name
- NCT07129941
- Testing
- Unified Protocol
- Where
- Norway
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Alcohol Problems, Post-Traumatic Stress Disorder
The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans
Veterans seeking to improve their romantic relationships when high conflict and unhealthy dynamics (e.g., aggression) are present remain underserved within the VHA with few treatment options.
- Trial name
- ACT-SHARE (NCT06746727)
- Testing
- Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Anxiety Symptoms, Depressive Symptoms
Project COPE-Spain (Coping Options for Parent Empowerment)
The goal of this study trial is to establish the preliminary clinical utility of the COPE program (Coping Options for Parent Empowerment) adapted for caregivers of adolescents in the Spanish context.
- Conditions
- Anxiety Symptoms, Depressive Symptoms, Parental Stress
- Trial name
- COPE-ES (NCT07006220)
- Testing
- COPE Program
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Universidad Nacional de Educación a Distancia
HIV/AIDS, Violence
Effectiveness of Transdiagnostic Cognitive Behavioral Therapy for Improving HIV Treatment Outcomes in South Africa
This study will evaluate the impact of the Common Elements Treatment Approach (CETA), an evidence-based intervention comprised of cognitive-behavioral therapy elements, at improving HIV treatment outcomes among women with HIV who…
- Trial name
- CETA (NCT04242992)
- Testing
- CETA, Short Message Service (SMS) text reminders
- Where
- South Africa
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Boston University
Heart Failure, Depression
Assessing the Acceptability and Feasibility of COMPASS
Heart failure (HF) is a complex clinical syndrome characterized by the inability of the heart to pump an adequate amount of blood.
- Conditions
- Heart Failure, Depression, Anxiety
- Trial name
- NCT05081947
- Testing
- COMPASS
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- King's College London