Clinical trials: Transfemoral Amputees
Transfemoral Amputees, Kinesiology Taping
The Effect of Kinesiology Taping on Lumbar Region Structures and Balance in Transfemoral Amputees
With the initiation of prosthesis use following lower extremity amputations, the body shows biomechanical changes according to the amputation level, and as a result, it develops adaptation mechanisms on both the healthy and…
- Trial name
- NCT04644991
- Testing
- Kinesiology taping, Six minutes walking test
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Lower Limb Amputation
KinetiGait- Analysis of Depth Camera to Assist Gait Analysis for Unilateral Transtibial/Transfemoral Amputees
This is a feasibility study about implementing and using the KinetiGait gait analysis system in clinical practice to enhance the rehabilitation of service members with lower limb disfunction.
- Trial name
- NCT04431817
- Testing
- KinetiGait
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Unilateral Transfemoral Amputation
Study of Medial-Lateral Center of Pressure Displacement in Unilateral Transfemoral Amputees
The purpose of this study is to examine the path and velocity of the center of mass (CoM) and center of pressure (CoP) during double support of persons walking with a unilateral above-the-knee prosthesis and determine the effects…
- Trial name
- NCT02299674
- Testing
- Level overground ambulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Southern California Institute for Research and Education
Osseointegrated Implants, Bone Mineral Density
Osseointegrated Transdermal Femoral Amputation Prostheses
Femur amputated patients often suffer from several problems with conventional socket prosthesis. Some experience changes in gait, discomfort when sitting, altered skin conditions (infection, irritation, rashes, sweat), phantom…
- Trial name
- NCT05736640
- Testing
- Denosumab
- Volunteers
- 6 people
- Sponsor
- University of Aarhus
Transfemoral Amputation
Osseointegrated Prostheses for the Rehabilitation of Amputees
Patients with transfemoral amputations (TFA) frequently experience problems related to the use of socket-suspended prostheses 1-3. These problems increase with short or deformed stumps 4.
- Trial name
- OPRA (NCT01725711)
- Testing
- OPRA Implant System
- Where
- Sweden
- Volunteers
- 51 people
- Sponsor
- Integrum
Transfemoral Amputation
Microbiome and Metagenome in Percutaneous Osseointegrated Prostheses (MMPOP)
The purpose of this study is to investigate the clinical implementation of a new percutaneous prosthetic attachment system by determining the resident microbial ecology of the implant exit site and to simultaneously study the…
- Trial name
- MMPOP (NCT02564432)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA Office of Research and Development
Lower Limb Amputation Above Knee (Injury)
Decoding Motion Planning Using Cortical Potentials
The team will investigate the user's intention to move by using cortical activity during a sit to stand movement performance in people with a transfemoral amputation and able-bodied individuals.
- Trial name
- NCT04325516
- Testing
- Daily activities
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Prostheses and Implants
Advanced Prosthetic Devices for Lower Limb Amputees
Lower limb amputation is an emerging global health concern. Currently, there are over 1.6 million amputees in the U.S. and around 6000 new amputations are recorded per annum in the UK.
- Trial name
- NCT04197011
- Testing
- prosthetic device
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Amputation
Effect of Socket Wall Height With Vacuum Suspension for Above Knee Amputees
Individuals with transfemoral (TF) amputation (above the knee amputation) may benefit from a socket that uses vacuum assisted suspension (VAS) to hold the socket onto the amputated limb.
- Trial name
- NCT01559909
- Testing
- Vacuum assisted socket technology (Harmony System, Otto Bock Healthcare)
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Stony Brook University
Traumatic Transfemoral Amputation, Painful Bone Spur
Efficacy of Extracorporeal Shockwave Therapy on Painful Bone Spur in Traumatic Transfemoral Amputees
Painful bone spur is one of the causes of residual limb pain in individuals with traumatic lower extremity amputation and can be a significant problem in rehabilitation clinics.
- Trial name
- NCT07440550
- Testing
- Extracorporeal shockwave therapy (ESWT), Therapeutic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Amputation, EMG
The Dynamic Postural Changes in Transtibial and Transfemoral Amputees
This research was planned to examine how unpredictable movements on the support surface will affect muscle activation and kinematic parameters in individuals with transtibial and transfemoral amputations.
- Conditions
- Amputation, EMG, Balance, Perturbation
- Trial name
- NCT05301270
- Testing
- EMG Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Amputation, Transfemoral Amputation
Investigation on a New Power Knee Firmware Update on Gait and Daily Life Activities for Transfemoral Amputees
The goal of this interventional study is to investigate a new firmware in development for Power Knee on gait and daily life activities in unilateral transfemoral amputees.
- Trial name
- NCT06620861
- Testing
- Power Knee Firmware Update, Power Knee Current Marketed Firmware
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Össur Iceland ehf
Amputation, Prosthesis User
Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators
The goal of this study is to find out if using microprocessor-controlled prosthetic knees (MPKs), prosthetic knees with a built-in computer, improves health outcomes related to falls in adults who use above-knee prostheses.
- Conditions
- Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower
- Trial name
- NCT06937242
- Testing
- Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hanger Institute for Clinical Research and Education, LLC
Amputation Stump
Characterization of Residual Limb Volume Changes in Transfemoral Amputees
This study quantifies residual limb volume fluctuations affecting transfemoral amputees due to the prosthesis doffing, physical activity, and testing time.
- Trial name
- NCT04709367
- Testing
- 3D optical scan
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istituto Nazionale Assicurazione contro gli Infortuni sul Lavoro
Lower Limb Amputation, Older Adults
Study of WiiFit to Enhance Walking in Older Adult Amputees
WiiNWALK is a 4 week physical activity, with the intervention of a WiiFit, targeted to improve walking capacity in individuals with either a unilateral below-knee or above-knee amputation.
- Trial name
- WiiNWalk (NCT01942798)
- Testing
- Nintendo Wii, Wii Big Brain Academy Degree program
- Where
- 5 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Transfemoral Amputees
Impairment Oriented Versus Task Oriented Gait Training In Transfemoral Amputee Rehabilitation.
This study examines the comparison between Impairment Oriented versus Task Oriented Gait Training in Transfemoral Amputee Rehabilitation.
- Trial name
- NCT07578051
- Testing
- Impairment oriented (Group A), Task oriented (Group B)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Foundation University Islamabad
Transfemoral Amputation, Balance Impairment
Effect of Dual-Task Training on Balance and Fall Risk in Lower Limb Amputees Using Prosthesis
This prospective randomized controlled trial aims to investigate the effect of dual-task training on balance and fall risk in individuals with unilateral transfemoral amputation using a prosthesis.
- Conditions
- Transfemoral Amputation, Balance Impairment, Fall Risk
- Trial name
- DTBALANCE (NCT07731698)
- Testing
- Dual-task training, Conventional Physiotherapy
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Amputation, Amputation, Traumatic
Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait
The goal of this study is to understand how providing power at the knee or ankle individually, or providing power at both the knee and ankle, impacts ambulation for K2 level transfemoral amputees.
- Conditions
- Amputation, Amputation, Traumatic, Amputation of Knee, Amputation; Traumatic, Limb
- Trial name
- NCT06433648
- Testing
- Ottobock CLeg4 + Ottobock foot, SRALAB Hybrid Knee + Polycentric Ankle, SRALAB Hybrid Knee + Passive Ankle
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Shirley Ryan AbilityLab
Lower Limb Amputation Above Knee (Injury)
C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
The aim of this post-market study is to confirm that the microprocessor controlled prosthetic knee components (C-Leg 3 and C-Leg 4) in comparison to mechanical knee joints can bring additional benefit to the users primarily on…
- Trial name
- NCT02765035
- Testing
- C-Leg 4, C-Leg 3
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 18 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Transfemoral Amputation, Limb Loss
A Biomechanical Evaluation of the Ossur Power Knee in Persons With Transfemoral Amputation
Microprocessor-controlled knees (MPKs) do not typically utilize motors to power joint rotation, but they automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the…
- Conditions
- Transfemoral Amputation, Limb Loss, Limb Absence
- Trial name
- OPKTFA (NCT06218238)
- Testing
- Powered prosthetic knee joint, Conventional microprocessor-controlled prosthetic knee joint
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development