Clinical trials: Transfer Impairment
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Pharmacists' Delivery of Education to Prevent Diabetes in the New Orleans Hospitality Industry
This is a one-year pilot study focused on prediabetes among hospitality workers in New Orleans, Louisiana. The project will assess prediabetes rates among the target population, evaluate the impact of pharmacist led lifestyle…
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Prediabetic State &Amp; High Risk Individuals on the Basis of Diabetes Risk Score
- Trial name
- NCT07451314
- Testing
- Linkage to Care, Educational, Healthy Lifestyle Tools
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Mild Cognitive Impairment, Cognitive Impairment
Study of Nasal Insulin to Fight Forgetfulness - Device Study
The SNIFF Device study will involve using a device to administer insulin through each participant's nose or intra-nasally. Insulin is a hormone that is produced in the body.
- Trial name
- NCT03857321
- Testing
- Insulin, intranasal nebulizer-like device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Mild Cognitive Impairment (MCI), Dementia
Exploring the Impact of Dementia Prevention Programs Using Robots as Intervention Tools on Community Elderly
The purpose of this study is to intervene in the cognitive functions of the community elderly through the "Robot Dementia Prevention Course" training.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Cognitive Decline, Psychological Well-being
- Trial name
- NCT06984458
- Testing
- Robot Dementia Prevention Course
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Mild Cognitive Impairment, Cognitive Impairment
SNIFF - Combo INI+EMPA Trial
The proposed pilot study will provide safety and efficacy preliminary data regarding singular and combined effects of two therapeutic approaches, intranasal insulin and treatment with the sodium-glucose cotransporter type 2…
- Conditions
- Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT05081219
- Testing
- Insulin (Humulin® R U-100), Empagliflozin 10 MG, Aptar Pharma CPS Intranasal Delivery Device
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Mild Cognitive Impairment (MCI), Healthy Aging
Computerized Cognitive Training in Healthy Older Adults and Mild Cognitive Impairment
The overall objective of this study is to assess the effect of an adaptive computerized cognitive training program for executive functions (CogniFit platform) on improving these functions in older adults, both healthy and with…
- Trial name
- COGNI-AGE (NCT07598409)
- Testing
- Computerized Cognitive Training, Active Control Computerized Activities
- Where
- 2 sites in Spain
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio de Nebrija
Mild Cognitive Impairment, Cognitive Impairment
SNIFF - 3-Week Aptar CPS Device
The SNIFF 3-Week Aptar Device study will involve using a device to administer insulin or placebo through each participant's nose or intra-nasally. Insulin is a hormone that is produced in the body.
- Conditions
- Mild Cognitive Impairment, Cognitive Impairment, Alzheimer Disease, Early Onset
- Trial name
- NCT05006599
- Testing
- Insulin (Humulin® R U-100), Aptar Pharma CPS Intranasal Delivery Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Lipid-induced Insulin Resistance
Fat and Transcapillary Insulin Transport
There is a current debate whether impaired insulin-mediated microvascular perfusion limits the delivery of hormones and nutrients to muscle and whether short term FFA elevation affects transcapillary transport of insulin and…
- Trial name
- FATRAIN (NCT01482455)
- Testing
- Elevation of FFA during OGTT, Elevation of FFA during Clamp
- Where
- Austria
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center
Type 2 Diabetes
Type 2 Diabetes and Exercise Function in Single Leg Exercises
This study plans to learn more about the effects of type 2 diabetes (T2DM) on exercise blood flow and muscle oxygen uptake. This study will evaluate \& compare exercise function during single leg plantar flexion exercise in a…
- Trial name
- NCT01793909
- Testing
- Single Leg Exercise Training
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcohol Use Disorder (AUD), Alcoholism
Assessing Habitual, Goal-Directed, and Pavlovian Influences in Alcohol Use Disorder
The first aim of this study is to establish the role of maladaptive reliance on habits for impaired control in addiction, employing a novel task - the Action-Sequence-Task (AST), which assesses interference between habitual and…
- Conditions
- Alcohol Use Disorder (AUD), Alcoholism, Substance Use Disorders
- Trial name
- ReCoDe (NCT06701500)
- Testing
- Pavlovian-to-instrumental transfer (PIT) paradigm, Action Sequence Task (AST), Basic psychological assessment (interview)
- Where
- Germany
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Math Learning Disability, Child Development
Interventions in Mathematics and Cognitive Skills
The purpose of this study is to investigate neurocognitive mechanisms underlying response to intervention aimed at enhancing, and remediating weaknesses in, numerical skills in children, including those with mathematical learning…
- Conditions
- Math Learning Disability, Child Development, Developmental Disability, Learning Disabilities
- Trial name
- NCT05201534
- Testing
- Interventions in Mathematics and Cognitive Skills - Experimental, Interventions in Mathematics and Cognitive Skills - Active Comparator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Stanford University
Developmental Language Disorder, Language Impairment
The Relationship Between Child Language Proficiency and Language of Treatment on the Outcomes of Bilingual Children with Developmental Language Disorder
Of the 12 million children in the USA growing up bilingual, about 1 million experience Developmental Language Disorder (DLD), a disorder in language learning and use.
- Trial name
- NCT06085300
- Testing
- Sentence recast
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Houston
Smoking
Young Smokers Have Impaired Airway Defense
Background: Smoking is a key factor for development and progression of chronic obstructive pulmonary disease (COPD). Although persons with COPD often have concomitant nasal disease, there are few studies that report physiological…
- Trial name
- NCT01877291
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Age-related Hearing Impairment 1, Personal Communication
Baltimore HEARS: Hearing Health Equity Through Accessible Research & Solutions
Age-related hearing loss is highly prevalent and hearing health care is underutilized. The primary objective of the proposed randomized controlled trial is to investigate the efficacy of a community health worker (CHW)-delivered…
- Trial name
- HEARS (NCT03442296)
- Testing
- Baltimore HEARS
- Where
- 2 sites in United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hearing Loss, Dementia
HEARS-SLP: Providing SLP-Delivered Hearing Health Care to Individuals With Cognitive Impairment
Building upon the HEARS audiologist-community health worker (CHW) model, this study intervention will be delivered by a speech-language pathologist (SLP).
- Conditions
- Hearing Loss, Dementia, Cognitive Impairment
- Trial name
- NCT06008782
- Testing
- HEARS-SLP device, HEARS-SLP program
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Transfer Impairment
Evaluating the CG ASSIST Program for Caregiving Dyads
The CG ASSIST Project is a four-year study for older Veterans with transfer impairments and informal caregivers. CG ASSIST is an in-home training program for dyads designed to teach Veterans how to safely, skillfully, and (when…
- Trial name
- CG ASSIST (NCT02021565)
- Testing
- Immediate Intervention Group, Delayed Intervention Control Group
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mild Cognitive Impairment, Cognitive Impairment
SNIFF Multi-Device Study 2
The SNIFF Device study will involve using one of three devices to administer insulin through each participant's nose or intra-nasally, accompanied by a lumbar puncture.
- Trial name
- NCT04199767
- Testing
- 20 IU Humulin® R U-100 (NDC: 0002-8215, Eli Lilly & Company), 40 IU Humulin® R U-100 (NDC: 0002-8215, Eli Lilly & Company)
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Impaired Health
Effectiveness of a Smartphone App for Adolescent Obesity Management
Though face-to-face treatment of childhood obesity can be effective, it is time consuming and costly. This study will test whether treatment can be delivered via an Android app and whether such treatment reduces obesity.
- Conditions
- Obesity, Impaired Health, Psychosocial Problem, Physical Activity
- Trial name
- NCT01804855
- Testing
- W82GO, smartphone application
- Where
- 2 sites in Ireland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Children's University Hospital, Ireland
Depressive Symptoms, Anxiety
Asynchronous Techniques for the Delivery of Empirically Supported Psychotherapies
The aim of this study is to test the feasibility, acceptability and efficacy of methods for delivering mental health support when real-time communication is not possible (e.g.
- Conditions
- Depressive Symptoms, Anxiety, Stress, Impairment
- Trial name
- NCT05122429
- Testing
- e-Health Treatment
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Impaired Oxygen Delivery, Critically Ill Patient
Non-Invasive Measurement of SjvO2 Using Near Infrared Spectroscopy in Critically Ill Patients
ScvO2 is an important parameter in the management of critically ill patient. The only way to measure it is to have an internal jugular or subclavian central venous catheter.
- Trial name
- NIRS-SCJVO2 (NCT04624009)
- Where
- 2 sites in Switzerland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva