Clinical trials: Transgender Individuals
Traumatic Brain Injury, Cervical Spinal Cord Injury
Restorative Neuromodulation for Upper Extremity Functions
The objective of this research study is to find the efficacy of trans-spinal electrical stimulation, a non-invasive neurostimulation method to modulate the functions of spinal cord neurocircuits, on improving upper-extremity…
- Trial name
- NCT04183998
- Testing
- Trans-spinal Electrical Stimulation (tsES)
- Where
- Hong Kong
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Obesity, Motor Activity
Influence of Exercise on Trans Fatty Acids
Introduction: The metabolism of fatty acids in plasma is modulated by their availability in plasma. Individuals with increased weight have increased plasma fatty acids and physical exercise seems to favor the metabolic responses…
- Conditions
- Obesity, Motor Activity, Fatty Acids, Lipid
- Trial name
- NCT03170973
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Faculdade Adventista da Bahia
Hypercholesterolemia
Effects of Various Higher Fat and Lower Fat Snacks on Cardiovascular Risk Factors in Men and Women.
The purpose of this study is to determine whether snacks differing in fat amount and type result in changes in cardiovascular disease risk factors in men and women who have mildly elevated cholesterol levels.
- Trial name
- NCT00349765
- Testing
- higher fat, high polyunsaturated fat diet, higher fat, high saturated and trans fat diet, lower fat diet
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
HIV
A Clinical Study of Alimatravir (MK-8527) in Transgender (Trans) and Gender Diverse Individuals on Gender-affirming Hormone Therapy and at Low Likelihood of Human Immunodeficiency Virus (HIV)-1 Exposure (MK-8527-018)
The goal of this study is to learn about the safety of alimatravir (MK-8527) in transgender and gender-diverse people and if they tolerate it.
- Trial name
- EXPrESSIVE-18 (NCT07850609)
- Testing
- Alimatravir
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Interstitial Cystitis, Chronic Prostatitis
Chronic Pelvic Pain Study of Individuals With Diagnoses or Symptoms of Interstitial Cystitis and/ or Chronic Prostatitis
The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder Syndrome (PBS) in men and…
- Trial name
- MAPP-EP (NCT01098279)
- Where
- 8 sites in United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Gender Affirming Communication Skills
Simulated Conversation Training for Mental Healthcare Providers to Improve Care for Transgender and Gender Nonconforming Individuals
Phase I: Eligible participants (n=20) will be recruited to participate in a feasibility evaluation of the client intake module to be developed.
- Trial name
- NCT04820088
- Testing
- Computer based role play trianing
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- SIMmersion, LLC
Transgender Individuals, Gender Incongruence
Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study
The goal of this observational study is to understand the factors influencing the well-being and health of transgender and gender-diverse (TGD) individuals undergoing gender-affirming therapies in Switzerland.
- Trial name
- SPECTRA (NCT06774053)
- Testing
- Group A (start of GAHT), Group B (on-going GAHT), Group C (GAS)
- Where
- 3 sites in Switzerland
- Volunteers
- 600 people
- Sponsor
- University Hospital, Basel, Switzerland
Gender Affirmation Surgery, Perioperative Care
Support for Transgender and Non-Binary Individuals Seeking Vaginoplasty Study
The STRIVE study is the first national randomized trial to focus on improving well-being, access to surgical care and other health outcomes for transgender and nonbinary (referred to as trans) people seeking genital…
- Conditions
- Gender Affirmation Surgery, Perioperative Care, Transgender Health
- Trial name
- STRIVE (NCT06436560)
- Testing
- STRIVE Peer Support Intervention
- Where
- 9 sites in United States
- Volunteers
- 290 people
- Sponsor
- Oregon Health and Science University
Parkinson Disease
Combining VNS With PT Interventions for Individuals With PD
The purpose of this study is to evaluate the combined effects of non-invasive neuromodulation (specifically transauricular Vagus Nerve Stimulation) with exercise interventions to improve physical function and quality of life in…
- Trial name
- VNS-PT-PD (NCT05871151)
- Testing
- taVNS, Exercise
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Fertility Preservation in Transgender Persons
Attitudes and Decision Regret Regarding Fertility Preservation in Transgender Individuals
The goal of this observational survey is to learn how transgender adults think and feel about saving their fertility before gender-affirming treatment.
- Trial name
- Fertilitrans (NCT07194226)
- Testing
- No intervention (observational study)
- Where
- Italy
- Volunteers
- 616 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Parkinson's Disease (PD), Gait Disorders
Effects of the Stimulation Site of tsMS With TMS on Functional Mobility in Individuals With Parkinson's Disease
This randomized clinical trial aims to compare the effects of two different trans-spinal magnetic stimulation (tsMS) application sites, cervical versus thoracic, when combined with repetitive transcranial magnetic stimulation…
- Conditions
- Parkinson's Disease (PD), Gait Disorders, Transcranial Magnetic Stimulation, Spinal Cord Stimulation
- Trial name
- NCT07488026
- Testing
- Repetitive Transcranial Magnetic Stimulation, Cervical Trans-spinal Magnetic Stimulation, Thoracic Trans-spinal Magnetic Stimulation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
HIV Prevention, Pre-exposure Prophylaxis
Stick2PrEP Cisgender Women and Trans Individuals
Taking a daily anti-HIV pill can protect people from HIV infection. This is called preexposure prophylaxis [PrEP]. Many cisgender women and trans individuals do not know this medication is available; others struggle to take the…
- Trial name
- S2P:CWTI (NCT05165745)
- Testing
- Individualized Feedback
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Columbia University
Amputation, Upper Limb
Study of Efficacy of the MyoTrain System in a Population of Individuals With Trans-radial Limb Loss
The investigators propose to evaluate the efficacy of MyoTrain in a prospective clinical study involving 16 individuals with trans-radial upper-limb loss over a period of 206 days.
- Trial name
- NCT05888428
- Testing
- MyoTrain, Motor Imagery
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Infinite Biomedical Technologies
Sexual Orientation Conflict Disorder
Anogenital Distance Differences Between Transgender Males and Female Individuals
This study evaluates the anogenital distance measurement differences between transgender male individuals and normal healthy female individuals.
- Trial name
- NCT03789331
- Testing
- Anogenital distance measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uludag University
Transgender
Gender Affirming Hormone Therapy and Immune Function in Trans Individuals - The GIFT Study
Our immune systems protect us from infection but can also cause disease, for example by attacking our own bodies (autoimmune disease), or driving chronic inflammation in conditions such as heart disease.
- Trial name
- GIFT (NCT07358897)
- Volunteers
- 500 people
- Sponsor
- Imperial College London
HPV Infection
HPV Self-testing in Transgender Individuals
Human papillomavirus (HPV) is a common virus that spreads through skin-to-skin contact. Some HPV types can cause changes in cells that lead to cancer and are known as 'high-risk' HPV (hrHPV).
- Trial name
- Self-TI (NCT05883111)
- Testing
- HPV DNA methylation assay
- Where
- 3 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Breast Cancer
Transgender and Gender Diverse Individuals Screening for Breast Cancer
The goal of this multicentric prospective study is to evaluate the incidence of Breast Cancer in transgender and gender-diverse population.
- Trial name
- GENESIS (NCT06347393)
- Testing
- Mammography and Breast Ultrasound
- Where
- Italy
- Volunteers
- 1,600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
SCA, Postural Balance
Trans-spinal Electrical Stimulation in Individuals With Spinocerebellar Ataxia
The main goal of this pragmatic clinical trial is to investigate the effects of trans-spinal tDCS in individuals with spinocerebellar ataxia (SCA) over some parameters of gait and postural control in real-world conditions…
- Conditions
- SCA, Postural Balance, Gait Ataxia
- Trial name
- NCT06267222
- Testing
- TRANSCRANIAL DIRECT CURRENT STIMULATION + exercises
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- Laura Alice Santos de Oliveira
Prosthesis User
Efficacy of a Vented Liner and Socket System for Individuals With Trans-femoral Amputation
The objective of the investigation is to measure the humidity within a transfemoral amputee's prosthesis during physical activity in a pre-heated room, using both the vented AeroFit system and a non-vented comparator.
- Trial name
- NCT05279885
- Testing
- Vented suspension system, Non-vented suspension system
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Jóna Valgerður Kristjánsdóttir
Transgender Individuals, QTc Interval
Protocol TRANS and QT Repolarization
The consequence of hormone-based treatment on cardiac electrophysiology in transgender individuals is poorly explored. We will investigate the effects of gender affirming hormone treatments on ventricular repolarization (ie.
- Trial name
- QTrans (NCT05865262)
- Testing
- ECG, blood test (assessing ionic and hormonal circulating levels)
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux