Clinical trials: Transgender Men
PrEP Test and Treat
Evaluation of a Facility-based Test, Treat, and Prevent HIV Program Among Men Who Have Sex With Men and Transgender Women in Thailand
This is a prospective observational cohort study that aims to enroll a total of 2000 Thai MSM and TG at five health facilities in four provinces of Thailand. Each participant will be followed for 18 months.
- Trial name
- PrEP (NCT02369887)
- Where
- Thailand
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
HIV Infections
A Study Evaluating Implementation Strategies for the Delivery of Cabotegravir in Low and High-Volume PrEP Site in the United States
This is a two-arm study evaluating the impact of two implementation strategy conditions, dynamic implementation and routine implementation on the feasibility of delivering of Cabotegravir PrEP in low and high-volume PrEP sites in…
- Trial name
- PILLAR (NCT05374525)
- Testing
- APRETUDE, Cabotegravir OLI
- Where
- 17 sites in United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- ViiV Healthcare
Sexual Functioning, Transgender Men
Evaluating Sexual Functioning in Trans Men During the Gender Affirmation Process: A Mixed Methods Study
Both sexual experiences and the process of gender transition initiated to reduce gender dysphoria carry cultural characteristics.
- Conditions
- Sexual Functioning, Transgender Men, Gender Affirmation Surgery
- Trial name
- ESFTMGAP (NCT07131267)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
HPV Infection
HPV Self-testing in Transgender Individuals
Human papillomavirus (HPV) is a common virus that spreads through skin-to-skin contact. Some HPV types can cause changes in cells that lead to cancer and are known as 'high-risk' HPV (hrHPV).
- Trial name
- Self-TI (NCT05883111)
- Testing
- HPV DNA methylation assay
- Where
- 3 sites in United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Transgender Men
Transmasculine Quality of Life and Sexual Function at Pre and Post Gender-affirming Hormonal Therapy
The goal of this prospective observational study is to evaluate the short-term effect of testosterone therapy on these issues among hormone naïve TM individuals. The main questions that aim to answer are : 1.
- Trial name
- transmen (NCT06482385)
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Outpatient Hysterectomy in Transmen
In-hospital Versus DAy Care Hysterectomy in Transgender Men
In this trial 2 groups of transmen who are getting a hysterectomy will be compared: inpatient vs outpatient.
- Trial name
- IDAH (NCT05393583)
- Testing
- Outpatient hysterectomy, Inpatient hysterectomy
- Where
- Belgium
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Clinical Competence, Medical Education
Intervention for Medical Student to Promote Cervical Cancer Screening Among Latinx Transmasculine Individuals
The team aims to test the effectiveness of an intervention to increase gender-affirming cervical cancer prevention behaviors targeted at medical students studying in Puerto Rico and Florida.
- Conditions
- Clinical Competence, Medical Education, Cervical Cancer Screening
- Trial name
- CC-Trained (NCT06844097)
- Testing
- Cervical Cancer Trans Inclusive Education (CC-TRAINED) Module, Disaster Preparedness Course
- Volunteers
- 60 people
- Sponsor
- Ponce Medical School Foundation, Inc.
Hormone Therapy
Hormone Therapy and Angiotensin-Dependent Arterial and Renal Vasoconstriction in Humans
1. to investigate the association between route of administration of exogenous estrogen (transdermal vs. oral) and cardiorenal risk in cisgender (gender identity aligning with sex at birth) and transgender (gender identity not…
- Trial name
- NCT05442463
- Testing
- Captopril Tablets, Iohexol
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Calgary
HPV
Acceptability of the HPV Vaccine and Anal HPV in Transgender Women and Men Who Have Sex With Men: A Pilot Study
Protocol Title: "Acceptability of the Human Papillomavirus (HPV) Vaccine and Anal HPV in Transgender Women (TGW) and Men Who Have Sex with Men (MSM): A Pilot Study.
- Trial name
- HPVac (NCT06588257)
- Testing
- Non-infectious adjuvanted recombinant nonavalent HPV vaccine
- Where
- Argentina
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Fundación Huésped
Transgender Persons, Sexual Health
The Experiences of Erotic and Sexual Risk of Transgender Men: Exploratory Research Design
Transgender male (TM) is the minority and difficult to reach-up group. Therefore, there is a lack of research on private issues involving TM, such as sex, eroticism, and sexual risk behavior.
- Trial name
- NCT05187442
- Testing
- questionnaire, interview
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University
HIV
PrEP With TDF/FTC to Prevent HIV-1 Acquisition in Young MSM and Transgender Women of Color
This is a 48-week prospective observational study that will allow testing of the hypothesis that a program in which pre-exposure prophylaxis (PrEP) is administered to young men of color who have sex with men (yMSMc) in a…
- Trial name
- NCT02367807
- Testing
- Emtricitabine and tenofovir disoproxil fumarate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Philadelphia Fight
HIV Infections, Risk Reduction
Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study
PrEP (pre-exposure prophylaxis) is an effective prevention strategy in which HIV-negative individuals take antiretroviral drugs (tenofovir disoproxil fumarate and emtricitabine - TDF/FTC) to reduce HIV acquisition.
- Conditions
- HIV Infections, Risk Reduction, Risk Behavior, Risky Health Behavior
- Trial name
- Seroincidence (NCT05674682)
- Testing
- HIV testing
- Where
- 2 sites in Brazil
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Hematoma, Seroma
Progressive Tension Sutures in Gender Affirming Mastectomy
50 patients seeking gender affirming mastectomy will be treated with different closure techniques in each side of their chest - one side will receive progressive tension sutures between pectoral fascia and the mastectomy flap…
- Trial name
- NCT04818580
- Testing
- Progressive Tension Sutures
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- NYU Langone Health
Prostate Neoplasm
PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not?
This evaluates the detection rates of prostate cancer by MRI-targeted prostate biopsy compared to standard 12-core trans-rectal ultrasound guided (TRUS) prostate biopsy.
- Trial name
- PRECISION (NCT02380027)
- Testing
- MRI, MRI-targeted biopsy, TRUS-biopsy
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University College, London
Men or Transgender Women Who Have Sex With Men
HIV Self-Testing AND Uptake and Retention of PrEP Among Older Adolescent MSM and TGW
This will be a prospective study that will enroll up to 600 older adolescent MSM and TGW from community-based clinics in Bangkok, Chonburi, Chiang Mai, and Songkhla.
- Trial name
- NCT03745495
- Where
- 7 sites in Thailand
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Thai Red Cross AIDS Research Centre
HIV Infections
PrEP Among MSM and TG in Myanmar
HIV is concentrated among key populations in Myanmar. Globally, HIV-prevalence among transgender (TG) women is one of the highest; laboratory-confirmed prevalence is reported up to 40%.
- Trial name
- PrEP (NCT04781426)
- Testing
- Tenofovir Disoproxil Fumarate (TDF) 300 mg
- Where
- Burma
- Volunteers
- 200 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Anal High-grade Squamous Intraepithelial Lesion
Anal HSIL Screening Algorithm
This the propose to use the Multiphase Optimization Strategy Trial (MOST) design to identify an anal HSIL screening algorithm which is most suitable in terms of effectiveness, efficiency, and economy.
- Trial name
- 0007/65 (NCT05531799)
- Testing
- OPTIMIZATION PHASE
- Where
- Thailand
- Volunteers
- 950 people, healthy volunteers welcome
- Sponsor
- Institute of HIV Research and Innovation Foundation, Thailand
Gender Dysphoria, Gender Identity
Early Mental Response - The EMRE Study
Primary question: Does transgender men's experience of gender incongruence improve within 6 weeks of hormonal treatment compared to placebo? Long before any bodily changes occur.
- Conditions
- Gender Dysphoria, Gender Identity, Gender Issues
- Trial name
- EMRE (NCT05649605)
- Testing
- Testosterone treatment
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Karolinska University Hospital
HIV Infections, HIV
Using Mobile Technology and Incentives With Men Who Have Sex With Men and Transgender Women for HIV Prevention
This project called Mobile Technology and Incentives (MOTIVES) aims to increase engagement with HIV prevention information and improve testing frequency among Latino/a men who have sex with men (MSM) and transgender women (TGW).
- Trial name
- MOTIVES (NCT03144336)
- Testing
- Information provision, Weekly quizzes, Rewards for testing HIV-negative
- Where
- United States
- Volunteers
- 217 people
- Sponsor
- RAND
Social Network Strategy, HIV Self Testing
SNS to Increase HIV Testing Uptake and Linkage to Double Cascade Services Among Adolescent MSM and TGW in Thailand
UNAIDS aims to end AIDS by 2030 using "90-90-90" diagnosis-treatment-viral suppression targets. Thailand has achieved elimination of HIV mother-to-child transmission, but continues to see new infections among adolescent men who…
- Conditions
- Social Network Strategy, HIV Self Testing, Men Who Have Sex With Men
- Trial name
- NCT04953858
- Testing
- Social network strategy (SNS)
- Where
- Thailand
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University