Clinical trials: Transgenderism
Transsexualism
First Australian National Trans Mental Health Study
This is an Internet-based survey of transgender and transsexual (trans) people aged 18 years and older living in Australia. This population has received limited attention from public health researchers, planners, and…
- Trial name
- NCT02119377
- Testing
- questionnaire
- Where
- Australia
- Volunteers
- 946 people, healthy volunteers welcome
- Sponsor
- Curtin University
Transgenderism
Transgender Men, Non-binary Persons and Testosterone Treatment BODY IDENTITY CLINIC
The aim of this study is to investigate transgender men and non-binary persons before and during testosterone treatment. The study will focus on: Cardiovascular status Muscle strenght and power Aggression and quality of life…
- Trial name
- NCT04254354
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Marianne Andersen
Transgenderism, Gender Identity
Quality of Life of Transgender People - Implementation and Monitoring of an Online Cohort (e-QoL-Trans)
Transgender people have an identity or an expression gender that differs from the sex assigned to them at the birth. Transgender people and their needs remain misunderstood, and more generally by society.
- Trial name
- e-QoL-Trans (NCT05761678)
- Testing
- Questionnaire quality of life
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Transgenderism
Transgender Estradiol Affirming Therapy
The purpose of this open label, pilot, randomized clinical trial is to evaluate the effectiveness, safety and tolerability of estrogen use in transgender female and the degree of testosterone suppression achieved in this…
- Trial name
- TREAT (NCT05010707)
- Testing
- Transdermal patch, Pro-thrombotic markers, Metabolic markers
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Transgenderism, Depression
Reducing Transphobia Among Adolescents Through a Brief Video Intervention
The purposes of this new study are to test among adolescent viewers the utility of brief video-based interventions to: 1. reduce transphobia; 2.
- Trial name
- NCT04969003
- Testing
- Short videos
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Yale University
Transsexualism
A Common Polymorphism of the SRD5A2 Gene is Not Associated With Male-to-Female and Female-to-Male Transsexualism
Genetic variations, i.e. polymorphisms, may be associated with gender dysphoria, e.g. transsexualism. This study aims to identify such variations.
- Trial name
- NCT00435513
- Where
- Austria
- Volunteers
- 1,770 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Transsexualism, Transgenderism
Effects of Cross-sex Hormone Therapy on Eating Behavior, Metabolism, Energy Balance and Cardiovascular System
Current study aims to characterize five highly interconnected physiological systems in patients undergoing cross-sex hormone therapy - namely glucose and lipid metabolism, energy balance, eating behavior, functional brain…
- Conditions
- Transsexualism, Transgenderism, Adiposity, Eating Behavior
- Trial name
- HHS (NCT04838249)
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Testosterone, Transsexualism
Effect of Dose Fractionation of Testosterone Cypionate on Transgender Men with Erythrocytosis
A transgender man is someone with a male identity who were born with a vulva and vagina. The acquisition of masculine characters can come from surgery or from the use of testosterone.
- Conditions
- Testosterone, Transsexualism, Hematologic Diseases
- Trial name
- NCT05487794
- Testing
- Testosterone Cypionate 100 MG/ML
- Where
- Brazil
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Transgenderism, Reproductive Issues
Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
- Trial name
- NCT07092527
- Testing
- Testosterone Cypionate 50 milligrams per millileter (mg/mL) Injectable Solution
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Transgenderism, Cervical Cancer
Implementing HPV DNA Self-Collection to Increase Rates of Cervical Cancer Screening in Transgender Men
Transgender men are individuals born genetically female that have a gender identity that is incongruent with their biological sex.
- Conditions
- Transgenderism, Cervical Cancer, Human Papilloma Virus
- Trial name
- NCT04154358
- Testing
- HPV testing
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Augusta University
Transgenderism, Erectile Dysfunction
Epithesis Versus Prosthesis in Post-phalloplasty Transgender Patients.
Transgender and gender diverse (TGD) individuals most often choose for phalloplasty as a means to create masculine external genitalia.
- Conditions
- Transgenderism, Erectile Dysfunction, Prosthesis Durability, Gender Dysphoria
- Trial name
- EROS (NCT05883553)
- Testing
- Usability and added value of device within sexual activity
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Transgenderism
Sociological Study of the Life Courses of Young TRANSgender Patients
The number of people consulting for a request related to trans identity is increasing sharply. The study monocentric qualitative study of discursive material aims to describe the diversity of practices and discourses mobilized by…
- Trial name
- ParTransRep (NCT06221163)
- Testing
- collection of biographical and sociological data
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Gender Dysphoria, Voice Disorder Due to Transsexualism
Investigation of the Perceptual and Acoustic Voice in Trans Man
The aim of the study is to follow acoustic and perceptual voice changes in trans men during hormone therapy and to examine the relationship between psychosocial and vocal characteristics and testosterone measured in routine…
- Conditions
- Gender Dysphoria, Voice Disorder Due to Transsexualism, Transgender Persons, Hormone Replacement Therapy
- Trial name
- NCT05166083
- Testing
- Testosterone Hormon Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Transgenderism, HIV Infections
Transgender Men's Perspectives on HIV Risk and HIV Prevention Interventions
The goal of this pilot study is to gather and analyze qualitative data from focus groups with Transgender men who have sex with men (TMSM) to learn more about the life experiences unique to TMSM that influence their attitudes and…
- Trial name
- NCT05666102
- Testing
- Transgender men's perspectives on HIV risk and HIV prevention interventions
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Transsexualism, Surgery
Use of an External Erectile Device in Transgender Man Following Phalloplasty
The purpose of this study is to test whether an external erectile prosthesis (The Elator™) is a feasible alternative to internal erectile prostheses for transgender men who have undergone a phalloplasty with glansplasty and wish…
- Conditions
- Transsexualism, Surgery, Sex Behavior, Erectile Dysfunction
- Trial name
- ProstHEsis (NCT03823014)
- Testing
- Elator
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
HIV/AIDS, STI
Transgender Cohort Study of Gender Affirmation and HIV-related Health
This observational research study will evaluate medical gender affirmation delivered in primary care as an intervention to reduce disparities in HIV-related outcomes (e.g., low rates of PrEP uptake for HIV-uninfected patients…
- Conditions
- HIV/AIDS, STI, Gender Dysphoria, Transsexualism
- Trial name
- NCT03595956
- Testing
- Medical gender affirmation
- Where
- United States
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Fenway Community Health
Transgenderism, Erectile Dysfunction
Erectile Aid Use in Post-phalloplasty and Post-metoidioplasty Transgender Patients
This study seeks to explore the various methods used by transgender men for sexual intercourse following phalloplasty or metoidioplasty, focusing on their satisfaction with different erectile aids, as well as the satisfaction of…
- Conditions
- Transgenderism, Erectile Dysfunction, Gender Dysphoria, Sexual Dysfunction
- Trial name
- AID (NCT06639763)
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Surgery, Larynx
Voice Outcome of Glottoplasty, Cricothyroid Approximation, Thyroplasty, and Chondrolaryngoplasty
The purpose of this study is to measure the short- and long-term voice outcome and outcome predictors of glottoplasty, cricothyroid approximation, thyroplasty, and chondrolaryngoplasty using a prospective non-randomized…
- Conditions
- Surgery, Larynx, Transgenderism, Gender Dysphoria
- Trial name
- NCT06439290
- Testing
- Phonosurgery, Mastectomy/breast augmentation
- Where
- 2 sites in Belgium
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- University Ghent
Transgenderism, Fertility Issues
Transgender Caregivers' and Patients' Representations of Parenthood as Part of a Fertility Preservation Pathway
This research aims to understand the impact of fertility preservation consultation on transgender patients' projection and how the possibility of preserving gametes influences transgender people's transition paths, parenthood…
- Trial name
- TransFert (NCT06218446)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Transgenderism, Reproductive Issues
Androgen Effects on the Reproductive Neuroendocrine Axis
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
- Trial name
- NCT06450405
- Testing
- Testosterone Cypionate 50 MG/ML Injectable Solution
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego