Clinical trials: Transient
Malfunction; Catheter, Thrombosis
Prolonged Hemodialysis Catheter Survival With Copolymer Coating and Rt-PA
Surface thrombogenicity of standard double lumen catheters (stDLC) and surface modified film-coated domain structured double lumen catheters (fcDLC) consisting of a novel reactive polyurethane copolymer coating showed that in…
- Conditions
- Malfunction; Catheter, Thrombosis, Mechanical Complication of Hemodialysis Catheter
- Trial name
- PROCOPrt-PA (NCT01670474)
- Testing
- rt-PA (2mg/2mL) actilysis, rt-PA
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Centre Hospitalier du Centre du Valais
Diabetes Mellitus, Type 2, Non-alcoholic Fatty Liver Disease
Efficacy Study of Diacerein on Glycemic Control and Liver Fat in Type 2 Diabetes Subjects
This study is conducted to test the hypothesis that in uncontrolled type 2 diabetic adults treatment with diacerein will improve glycemic control and will reduce liver fat within a 24 month period.
- Trial name
- DGCLFT2DM (NCT02242149)
- Testing
- Diacerein
- Where
- Brazil
- Volunteers
- 84 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Haemorrhagic Stroke, Ischaemic Stroke
Digital Application for Stroke Health
Stroke is a leading cause of death and long-term disability worldwide. Despite substantial advances in acute stroke care, there remains a lack of evidence-based digital solutions to support patients after hospital discharge.
- Conditions
- Haemorrhagic Stroke, Ischaemic Stroke, Transient Ischemic Attack (TIA)
- Trial name
- DASH (NCT07511868)
- Testing
- StrokeApp, Standard care
- Where
- 7 sites in Austria
- Volunteers
- 500 people
- Sponsor
- VASCage GmbH
Vertebrobasilar Insufficiency, Ischemic Attack, Transient
Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS)
Patients with blockage of the blood vessels that supply blood to the back of the brain, known as vertebrobasilar disease (VBD), are at risk of having a stroke or temporary symptoms of a stroke known as transient ischemic attack…
- Conditions
- Vertebrobasilar Insufficiency, Ischemic Attack, Transient, Cerebrovascular Disorder, Brain Ischemia
- Trial name
- VERiTAS (NCT00590980)
- Where
- 6 sites in United States, Canada
- Volunteers
- 82 people
- Sponsor
- University of Illinois Chicago
Intracranial Atherosclerosis, Acute Stroke
Vessel Wall MR Imaging to Explore Sex-Differences of Intracranial Arterial Wall Changes After Suspected Stroke
Despite advances in stroke care, women continue to face worse outcomes after stroke than men. This disparity in outcomes may be related to biologic sex-differences that manifest in the development and progression of…
- Conditions
- Intracranial Atherosclerosis, Acute Stroke, Transient Ischemic Attack
- Trial name
- NCT03990545
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Non-Celiac Wheat Sensitivity
Non-Celiac Wheat Sensitivity: Permanent or Transient Condition?
Non-Celiac Gluten Sensitivity (NCGS) has been recently included among the gluten-related diseases. Patients suffering from NCGS are diagnosed after carefully excluding celiac disease (CD), and immunoglobulin E (IgE)-mediated…
- Trial name
- NCT02823522
- Testing
- Patients recruitment
- Where
- 2 sites in Italy
- Volunteers
- 280 people
- Sponsor
- University of Palermo
Cerebrovascular Accident, Cerebrovascular Accident, Acute
Comparison of the Efficacy of Ticagrelor Combined With ASA to ASA Alone in Patients With Stroke
Cerebrovascular disease is the main cause of death and severe long-term disability worldwide. Antiplatelet drugs are the main drugs for ischemic stroke and TIA.
- Trial name
- NCT04962451
- Testing
- ticagrelor + ASA
- Where
- China
- Volunteers
- 13,000 people
- Sponsor
- Peking University Third Hospital
Benign Prostatic Hyperplasia
Expander-2 Trial: Randomized Study to Evaluate Safety & Efficacy of the Urocross® Expander System & Retrieval Sheath
To demonstrate the safety and efficacy of the Urocross Expander System/Retrieval Sheath and the procedure to treat patients with symptomatic Benign Prostatic Hyperplasia (BPH).
- Trial name
- NCT05400980
- Testing
- Urocross implant
- Where
- 2 sites in United States
- Volunteers
- 240 people
- Sponsor
- Prodeon Medical, Inc
Non-small Cell Lung Cancer, Nivolumab
Cohort of Patients With NSCLC Treated With Nivolumab Under the ATU Program
Our study sought to examine nivolumab efficacy and safety in advanced NSCLC patients treated under the Temporary Authorization for Use (ATU, compassionate use) setting and describe their long-term clinical characteristics…
- Conditions
- Non-small Cell Lung Cancer, Nivolumab, Long-term Adverse Effects
- Trial name
- CLINIVO (NCT02933346)
- Where
- 72 sites in France
- Volunteers
- 907 people
- Sponsor
- Intergroupe Francophone de Cancerologie Thoracique
Acute Ischemic Stroke and Transient Ischemic Attacks
Computer Scan Based Analysing System on Improving Stroke Management Quality Evaluation
Study is designed for two parts, a perspective, multi-center, historial control study and a randomized controlled study of acute ischemic stroke patients.
- Trial name
- CASE (NCT03684629)
- Testing
- the response of KPI and corresponding suggestion
- Where
- China
- Volunteers
- 16,570 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Limb Ischemia, Ischemic Preconditioning
Model System for Transient Forearm Blood Vessel Dysfunction
This study will develop a model system that can be used to test medications for improving the ability of blood vessels to resist damage from diseases such as heart attack and stroke.
- Trial name
- NCT00453531
- Testing
- Limb Ischemia, Acetylcholine
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Ventilator Induced Lung Injury
Percutaneous Temporary Placement of a Phrenic Nerve Stimulator for Diaphragm Pacing, a First in Human Trial
Study conducted to confirm phrenic nerve stimulation using the Lungpacer LIVE Catheter, confirm capture of the diaphragm and confirm that the diaphragm can be paced in synchrony with mechanical ventilator breaths.
- Trial name
- NCT02670460
- Testing
- LIVE Catheter
- Where
- Paraguay
- Volunteers
- 24 people
- Sponsor
- Lungpacer Medical Inc.
Transient Ischemic Attack, Minor Ischemic Stroke
Dabigatran Treatment Following Transient Ischemic Attack and Minor Stroke
Objective: Demonstrate the safety of early use of dabigatran following TIA/minor stroke. Background: Although aggressive antithrombotic therapy has been shown to reduce the number of new ischemic events following stroke/TIA, this…
- Trial name
- DATAS (NCT01769703)
- Testing
- Dabigatran 110/150 mg BID
- Where
- Canada
- Volunteers
- 53 people
- Sponsor
- University of Alberta
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), HIV Infections
Lifestyle, Dietary Patterns, and Cardiometabolic Risk in Metabolic Dysfunction-Associated Steatotic Liver Disease Among People Living With HIV
Metabolic dysfunction-associated steatotic liver disease (MASLD), previously known as non-alcoholic fatty liver disease, is an increasingly recognized comorbidity in people living with human immunodeficiency virus (HIV).
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), HIV Infections, Non-Alcoholic Fatty Liver Disease, Liver Cirrhosis
- Trial name
- NCT07861594
- Volunteers
- 250 people
- Sponsor
- Assiut University
Syncope
The Management of Transient Loss of Consciousness and Suspected Syncope in European Emergency Departments
Prospective multi centre cohort study examining the clinical presentation, diagnostic tests, and management of adult Emergency Department (ED) patients presenting with Transient Loss of Consciousness (TLOC) either…
- Trial name
- SEED (NCT05571254)
- Testing
- Data collection
- Where
- 57 sites in Albania, Austria and 16 more
- Volunteers
- 952 people
- Sponsor
- NHS Lothian
Stroke (CVA) or Transient Ischemic Attack
Comparative Effects of Sensory Augmentation and Neuromodulation on Enhancing Motor Recovery Among Stroke Survivors
This study aims to evaluate the effectiveness of two rehabilitation techniques-Sensory Augmentation (using mirror therapy) and Neuromodulation (using transcranial direct current stimulation, tDCS)-in improving motor recovery…
- Trial name
- NCT07266662
- Testing
- Sensory Augmentation, Neuromodulation, Combination of Sensory Augmentation and Neuromodulation
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Cryptogenic Stroke or TIA, Atrial Fibrillation
Detection of Occult Paroxysmal AF in Cryptogenic Stroke or TIA Patients Using an Implantable Loop Recorder and Correlation With Genetic Markers.
Atrial fibrillation (AF) is the significant risk factor of ischemic stroke with incidence about 20% of all ischemic strokes. The undiagnosed AF in cryptogenic stroke patients could be present but not revealed by rutinne ECG.
- Trial name
- NCT02216370
- Where
- Slovakia
- Volunteers
- 125 people
- Sponsor
- University Hospital, Martin
Heart Failure, Dilated Cardiomyopathy
PITA-HF: Feasibility, Safety, and Tolerability
Heart failure affects over 25 million people worldwide and nearly 7 million adults in the United States alone. Nearly 25% of patients with heart failure have worsened disease burden from dyssynchronous ventricular contraction due…
- Trial name
- NCT04159454
- Testing
- PITA
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University
Stenosis of Arteriovenous Dialysis Fistula
Temporary vs.Long Term Hemodialysis Catheter on Central Vein Stenosis
Vascular access (VA) is the most important for carrying out hemodialysis, yet it may bring in complications and leads to hemodialysis quality decline.
- Trial name
- NCT04399564
- Testing
- temporary hemodialysis catheters, long-term hemodialysis catheters
- Volunteers
- 80 people
- Sponsor
- Shanghai Pudong Hospital
Dermal Fillers
Pivotal Study to Evaluate the Efficacy and Safety of Injection With LASBEAU Strong in Correction of Nasolabial Folds
Background: Nonsurgical injectable treatments have become popular for aesthetic purposes. In recent years, cross-linked hyaluronic acid (HA) fillers containing lidocaine have been used to correct the nasolabial folds.
- Trial name
- NCT06310863
- Testing
- LASBEAU Strong or Restylane Lyft injection as hyaluronic acid fillers
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
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