Clinical trials: Transient Hypothyroxinemia
Transient Hypothyroxinemia
Thyroid Function in Late Preterm Infants
Transient hypothyroxinemia (TH) is a condition characterized by low levels of serum thyroxine (T4) and normal levels of thyroid stimulating hormone (TSH).
- Trial name
- NCT00971555
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Transient Hypothyroxinemia of Prematurity (THOP)
Study of Thyroid Hormones in Prematures
The investigators hypothesize that continuous infusion of 4 µg/Kg/day T4 with 30 µg/Kg/day oral potassium iodide (KI) for 42 days from birth will reduce by 30% or more (from an estimated 30% to 21%) the proportion of extremely…
- Trial name
- THOP2 (NCT02103998)
- Testing
- thryoid hormone T4 + oral potassium iodide (KI) for 42 days, D5W - 5% dextrose water
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- New York Medical College
Transient Hypothyroxinemia
A Randomised Controlled Trial of Iodide Supplementation in Preterm Infants Follow-up at 2 Years
The purpose of this trial is to determine whether iodide supplementation of neonates born under 31 weeks gestation improves neurodevelopment measured at two years of age.
- Trial name
- I2S2 (NCT00638092)
- Testing
- sodium iodide, Sodium Chloride
- Where
- 19 sites in United Kingdom
- Volunteers
- 1,275 people
- Sponsor
- University of Oxford
Transient Hypothyroxinemia, Infant, Newborn
Thyroid Function in Term Infants With Respiratory Distress
This study was designed to evaluate the level of certain hormones (thyroid hormones and cortisol) in full term or close to full term infants who have respiratory distress severe enough to require respiratory support.
- Trial name
- NCT00293956
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Christiana Care Health Services
Transient Hypothyroxinemia of Prematurity
EEG Alterations in Preterm Infants With Thyroid Dysfunction
The aim of this study is to investigate differences in electroencephalography (EEG) evolution between preterm infants with and without transient hypothyroxinemia of prematurity (THOP) in order to find differences in the…
- Trial name
- EEG-THOP (NCT03493113)
- Testing
- EEG
- Where
- Belgium
- Volunteers
- 87 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Transient Hypothyroxinemia of Prematurity, Neurodevelopmental Abnormality
ASQ Scores of Transient Hypothyroxinemia of Prematurity
Transient hypothyroxinemia of prematurity (THoP) is defined as free thyroxine (FT4) level is below the reference values despite normal TSH level in preterm infant.
- Trial name
- NCT05901623
- Testing
- 'Ages and Stages Questionnaries' (ASQ)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Transient Hypothyroxinemia of Prematurity
Neurodevelopmental Impact of Treatment in Hypothyroxinaemia of Prematurity.
Nowadays, taking care of preterm birth is associated with an important increase in survival. This increased survival comes with impairment in neurodevelopmental outcomes in long term evaluation.
- Trial name
- NEO-TYR (NCT06346236)
- Testing
- L-thyroxine at a dose of 7.5 µg/kg/d for THOP, THOP without treatment, NoTHOP
- Where
- 3 sites in France
- Volunteers
- 373 people
- Sponsor
- Hospices Civils de Lyon
Hypothyroxinemia
L-Thyroxine Supplementation for Preterm Newborns Less Than 32 Weeks of Gestation With Hypothyroxinemia
Transient hypothyroxinemia of prematurity (THOP) is associated with neurodevelopmental impairment in preterm newborns < 32 weeks of gestation (WG).
- Trial name
- NCT01306227
- Testing
- L-Thyroxine, water
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens