Clinical trials: Transplant Donation
Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure
Long Term Minor Sibling Donor Well-Being
The goal of this research study is to understand what it is like for a young person to have a sick family member and what it is like to donate bone marrow or stem cells for a sick family member. Primary Aims: 1.
- Conditions
- Disorder Related to Bone Marrow Transplantation, Blood Stem Cell Transplant Failure, Disturbance of Emotions Specific to Childhood and Adolescence, Transmission, Blood, Recipient/Donor
- Trial name
- NCT00667784
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Kidney Transplant
The Paired Donation Consortium Paired Donation Program
The purpose of the protocol is to increase the number of living donor transplants by eliminating immune incompatibilities between donors and recipients through paired donation.
- Trial name
- NCT00374400
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Brain Death, Renal Failure
Understanding Family Refusal
The investigators plan a secondary data analysis of an existing dataset to examine how individual decision-making differs from family decision-making in organ donation.
- Trial name
- NCT04303624
- Testing
- Health sciences survey
- Volunteers
- 1,007 people, healthy volunteers welcome
- Sponsor
- Yale-NUS College
Renal Transplantation, Transplant Donation
Effect of a Preoperative Sensory Modulation Room on Pain, Anxiety, and Sleep in Kidney Transplant Patients
The goal of this prospective study is to evaluate whether preoperative exposure to a sensory modulation room can influence postoperative pain, anxiety, and sleep outcomes in adult living kidney donors and recipients.
- Conditions
- Renal Transplantation, Transplant Donation, Donor Nephrectomy
- Trial name
- SMRT-KT (NCT07533669)
- Testing
- Preoperative Sensory Modulation Session
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Nursing Students
The Effect of Peer Education on Stem Cell Donation in Nursing Students
The aim of the study is to determine the effect of peer education on stem cell donation in nursing students on their knowledge and attitudes towards being a stem cell donor.
- Trial name
- NCT05724459
- Testing
- Peer education
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
End Stage Renal Disease, End Stage Liver Disease
Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors
This study utilizes a web-based application to help patients on the organ transplant waitlist communicate patient's need for a living donor via social media and provide interested potential donors the opportunity to engage with…
- Trial name
- NCT03803423
- Testing
- The Donor App
- Where
- 6 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
End Stage Renal Disease, Transplantation
Live Kidney Donor Study - Cross-Sectional and Historical Cohort Study
Kidney transplantation from living donors has been shown to carry many benefits over deceased donor transplantation. Because of benefits such as shorter waiting times and improved outcome for transplant recipients, living kidney…
- Trial name
- NCT00951977
- Where
- 3 sites in United States
- Volunteers
- 7,029 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Living-Kidney Donors
Dietary Interventions During Living Kidney Donations
Monocentre, non-randomized, non-blinded, open-label interventional study to identification of relevant changes in molecular biology in proteome, phosphoproteome, lipidome, epigenome and transcriptome in pretransplant kidney…
- Trial name
- DILKID (NCT05709600)
- Testing
- Fasting mimicking diet, Ketogenic diet, Dietary restriction of sulfur containing amino acids
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Cologne
Kidney Transplant, Kidney Donor
Transforming Curiosity Into Donation
This is a multi-step study that will first create a preliminary living donor drop-out risk index (LD-DROP) by retrospectively identifying factors that contribute to the discontinuation of living donor evaluation.
- Conditions
- Kidney Transplant, Kidney Donor, Drop Out, High Risk
- Trial name
- NCT07793890
- Testing
- Living Kidney Donor Support
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Organ Finding
The Knowledge Levels and Attitudes of the People Living in Nevşehir on Organ Donation and Transplantation
In this descriptive study, the purpose was to determine the knowledge levels and attitudes of the people in Nevsehir, Turkey on organ donation.
- Trial name
- NCT02931318
- Testing
- Nevsehir
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Nevsehir Public Hospital
Transplant Donation
Information-Assisted Intervention for Potential Living Kidney Donors
This study aims to evaluate the effectiveness of an information-assisted intervention in enhancing knowledge, decision self-efficacy, and reducing decisional conflict among potential living kidney donors.
- Trial name
- NCT07243717
- Testing
- Information-Assisted Intervention
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Healthy Volunteers
Donation of Whole Blood by Healthy Volunteers After Mobilisation by Haematopoietic Growth Factor (Rhu-G-CSF = Granocyte)
Donation of whole blood by healthy volunteers after mobilisation by haematopoietic growth factor (rhu-G-CSF = Granocyte) for biological validation of a cell expansion automaton allowing the simultaneous production of several cell…
- Trial name
- CARDIOSTEM (NCT05594433)
- Testing
- Lenograstim
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CellProthera
Living Donor Nephrectomy
Kidney Donor Outcomes Cohort (KDOC) Study
Live donor kidney transplantation (LDKT) is important because its outcomes for recipients are superior to those of deceased donor transplantation, and it yields significant cost savings to the healthcare system overall.
- Trial name
- KDOC (NCT01427452)
- Where
- 7 sites in United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Kidney Disease
Transplant Social Worker Support for Live Kidney Donation in African Americans
Talking About Live Kidney Donation Support (TALKS) will study the effectiveness of education, behavior, and financial support interventions to improve consideration of live kidney transplantation/live kidney donation among…
- Trial name
- TALKS (NCT02369354)
- Testing
- TALKS Social Worker Intervention, Financial Assistance Intervention
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Duke University
End Stage Renal Disease
Explore Transplant @Home Within Kaiser Permanente Southern California
Today, there are 25 million Americans with chronic kidney disease (CKD) and 660,000 patients in full kidney failure, the final CKD stage, known as end stage renal disease (ESRD).
- Trial name
- NCT03389932
- Testing
- Patient-Guided
- Where
- United States
- Volunteers
- 977 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Kidney Transplant Donor
Modifiable Factors Affecting Racial Disparities in Kidney Donation
While many people offer to be evaluated at transplant centers as potential living donors to donate one kidney to someone they know, few ultimately donate. Racial/ethnic minorities are less likely to become living donors.
- Trial name
- NCT07793877
- Testing
- Not applicable- observational study
- Volunteers
- 2,332 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Stem Cell Donors
Impact of Stem Cell Donation on Unrelated and Related Donors' Health.
Haematopoietic stem cell donation represents a unique chance for curing patients affected with onchohaematologic and inherited diseases.If a related donor is unavailable a unrelated donor must be used.
- Trial name
- HPCDON (NCT06905704)
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
End Stage Kidney Disease
Evaluation of a Website on Living Kidney Donation for Hispanics
The purpose of this study is to increase understanding about living kidney donation (LKD) among Hispanic/Latino patients and public by increasing knowledge and positive attitudes about LKD.
- Trial name
- NCT01859871
- Testing
- Website Intervention
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Occurrence of Renal Dysfunction (GFR ≤ 60mL/(Min·1.73m2)) in Renal Transplant Recipients Within One Year After Kidney Transplantation
Multimodal Ultrasound in DBD Kidneys for Predicting Early Postoperative Renal Insufficiency Risk
The objective of this observational study is to investigate the multimodal ultrasound parameters of kidneys from brain-dead organ donors prior to donation, in order to construct a predictive model for assessing the risk of early…
- Trial name
- NCT07090512
- Testing
- Multimodal Ultrasound
- Where
- China
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Bei Wang
Organ Transplants
RCT Comparing Tailored Versus Targeted Organ Donation Video Education
The primary purpose of this 3-phase mixed methods design study is to investigate how presenting content at varying levels of audience specificity (generic, targeted, and tailored) influences organ donor registration behavior…
- Trial name
- NCT02676102
- Testing
- Control Group, Targeted Intervention, Tailored Intervention
- Where
- United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health