Clinical trials: Transplants and Implants
Transplants and Implants
Prednisone Withdrawal Versus Prednisone Maintenance After Kidney Transplant
The purpose of the study was to determine if rapid discontinuation of corticosteroids (also known as prednisone withdrawal) and maintenance immunosuppression with Prograf (tacrolimus) and CellCept (mycophenolate mofetil) while…
- Trial name
- NCT00596947
- Testing
- prednisone, rabbit antithymocyte globulin, Tacrolimus
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Pennsylvania
Transplants and Implants
B-Cell Targeted Carfilzomib Desensitization
The primary purpose of this study is to provide a preliminary evaluation of the safety and potential efficacy of carfilzomib in reducing HLA antibody levels in highly sensitized kidney transplant candidates.
- Trial name
- NCT02442648
- Testing
- Carfilzomib, Rituximab
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- E. Steve Woodle
Transplants and Implants
Myfortic or CellCept Gastrointestinal Effects in African American Kidney Recipients
Myfortic (enteric-coated mycophenolate sodium) has been shown to have similar effectiveness to CellCept (mycophenolate mofetil) in preventing rejection in kidney transplant recipients.
- Trial name
- NCT00522548
- Testing
- Enteric coated mycophenolate sodium, Mycophenolate mofetil
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Pennsylvania
Transplants and Implants, Hearing Loss
Evaluation of Performance and Usability of N6 in the Paediatric Population
The purpose of this study is to evaluate the performance and usability of the N6 system in children with the N5 system.
- Trial name
- NCT01800929
- Testing
- N6
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cochlear, Asia Pacific
Dental Implants, Transplants
Efficacy of Gingival Grafts During the Implantation Process on the Peri-implant Mucosa
This study aims to compare the changes in the peri-implant mucosa during the application of two soft tissue grafting methods, which are free gingival graft (FGG) and connective tissue graft (CTG) taken from the palatine in terms…
- Trial name
- NCT06065254
- Testing
- Efficacy of free gingival grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness, Efficacy of connective tissue grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness, No types of grafts will be made to improve the quality of the peri-implant mucosa
- Where
- Syria
- Volunteers
- 18 people
- Sponsor
- Damascus University
Actinic Keratoses, Carcinoma, Squamous Cell
Phase II AK Study in Organ Transplant Patients
The purpose of this study is to determine whether afamelanotide (CUV1647) is effective in reducing the number of actinic keratoses and squamous cell carcinomas developing in immune compromised organ transplant recipients, who are…
- Conditions
- Actinic Keratoses, Carcinoma, Squamous Cell, Organ Transplant Recipients
- Trial name
- NCT00829192
- Testing
- Afamelanotide (CUV1647)
- Where
- 12 sites in Australia, Belgium and 5 more
- Volunteers
- 200 people
- Sponsor
- Clinuvel Pharmaceuticals Limited
Idiopathic Parkinson´s Disease, Parkinson's Disease
A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease
This clinical trial is designed to test the safety and tolerability of the study intervention, RNDP-001, which will be implanted into the brain of study participants during a surgical procedure.
- Trial name
- NCT07106021
- Testing
- RNDP-001, Syringe Front-Loading Device
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- Kenai Therapeutics
Renal Transplant Rejection, Transplants and Implants
Prospective Pilot Study of Pre-Transplant Thymoglobulin Administration in Living Donor Renal Transplant Recipients
To determine how safe and effective giving Thymoglobulin before transplantation to patients who are going to be receiving kidney transplants.
- Trial name
- NCT00771745
- Testing
- Thymoglobulin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Cincinnati
Transplants and Implants
Quantitating the Impact of Plerixafor
The primary objective of this study is to conduct a proof of concept pilot study that will provide a preliminary evaluation of the safety of plerixafor alone or in combination with bortezomib on plasma cell mobilization, Human…
- Trial name
- NCT02522572
- Testing
- plerixafor, Bortezomib, plasmapheresis
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- E. Steve Woodle