Clinical trials: Transrectal Ultrasound
Cancer
Trial of Methoxyflurane With Periprostatic Local Anaesthesia to Reduce the Discomfort of TRUS B
A phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasound-guided prostate biopsy (Pain-Free TRUS B).
- Trial name
- TRUSB (NCT02604225)
- Testing
- Methoxyflurane
- Where
- 7 sites in Australia, New Zealand
- Volunteers
- 420 people
- Sponsor
- University of Sydney
Prostate Carcinoma
An Investigational Scan (18F-rhPSMA-7.3 PET-mpMRI) for Targeted Prostate Biopsy Using TRUS-MR Fusion Technique
This phase II trial evaluates an imaging technique called 18F-rhPSMA-7.3 positron emission tomography (PET)-multiparametric (mp) magnetic resonance imaging (MRI) in identifying tumor tissue in men suspected to have prostate…
- Trial name
- NCT06865768
- Testing
- Flotufolastat F-18 Gallium, Magnetic Resonance Imaging, Multiparametric Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Emory University
Gynecologic Diseases
Lidocaine Gel During Transrectal Sonography
The aim of this clinical trial is to evaluate the use of topical lidocaine gel in reducing pain associated with transrectal ultrasonography (TRS) in gynecologic field.
- Trial name
- NCT02567838
- Testing
- Lidocaine gel
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Kangbuk Samsung Hospital
Pain Relief During Prostate Biopsy
Combined Intravenous Diazepam, Local Periprostatic Nerve Block for Prostate Biopsy
Prostate biopsy under transrectal ultrasound (TRUS) guidance is considered the procedure of choice for diagnosing prostate cancer.
- Trial name
- NCT02935972
- Testing
- Diazepam, Lidocaine 1%, Diazepam and Lidocaine 1%
- Where
- Egypt
- Volunteers
- 336 people
- Sponsor
- Assiut University
Prostate Cancer
Brachytherapy in Treating Patients With Prostate Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy through seeds implanted into the prostate may kill more tumor cells.
- Trial name
- NCT00003312
- Testing
- iodine I 125
- Where
- 258 sites in United States, Canada
- Volunteers
- 95 people
- Sponsor
- Radiation Therapy Oncology Group
Prostate Cancer
European Multicenter Validation of PCaVision: A Head-to-Head Diagnostic Accuracy Study Comparing Multiparametric Transrectal Ultrasound to MRI for Clinically Significant Prostate Cancer Detection
The goal of this clinical trial is to learn if a new ultrasound-based imaging method (PCaVision) can accurately detect clinically significant prostate cancer in adult men (18 years and older) who are either undergoing initial…
- Trial name
- PCaVISTA (NCT06935487)
- Testing
- transrectal ultrasound of prostate (TRUS) with AI software algorithm, MRI prostate
- Where
- 10 sites in France, Germany and 4 more
- Volunteers
- 806 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Benign Prostatic Hyperplasia
Ultrasound-Guided Photoselective Vaporization of the Prostate
Benign prostatic hyperplasia (BPH) is a major cause of lower urinary tract symptoms (LUTS) affecting aging men. Medical therapy for BPH includes alpha adrenergic blockers and 5α-reductase inhibitors.
- Trial name
- NCT02346500
- Testing
- Transrectal Ultrasound
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Prostatic Neoplasms, Prostate Cancer
Multi-Center Trial of High-resolution Transrectal Ultrasound Versus Standard Low-resolution Transrectal Ultrasound for the Identification of Clinically Significant Prostate Cancer
This trial uses a ultra high-resolution ultrasound system and specialized transducer, intended for use in prostate imaging. The system's image resolution is significantly better than the standard of care, due to its higher…
- Conditions
- Prostatic Neoplasms, Prostate Cancer, Cancer of the Prostate
- Trial name
- NCT02079025
- Testing
- High-resolution ultrasound guided prostate biopsy, Standard ultrasound guided prostate biopsy
- Where
- 5 sites in United States, Canada
- Volunteers
- 1,676 people
- Sponsor
- Exact Imaging
Prostate Cancer XXX
The Effect of TENS on Pain, Complications and Comfort in Patients Who Had Prostate Biopsy With Transrectal Ultrasound
Prostate cancer is one of the most common types of malignancy in men. Transrectal Ultrasound Guided Prostate Biopsy (TRUSG-PBx) is considered the gold standard method.
- Trial name
- NCT06414421
- Testing
- Transcuten Electriacal Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Anal Fistula
Endorectal Three-dimensional Ultrasound in the Diagnosis of Cryptogenic Fistulas of the Rectum.
Prospective comparative parallel ultrasound diagnostic transrectal study in the diagnosis of cryptogenic fistulas of the rectum
- Trial name
- NCT03743701
- Testing
- The method of transrectal ultrasound in В-mode, The method of transrectal ultrasound examination using three-dimensional image reconstruction.
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Male, Ultrasonography
Intraprostatic Injection of Botulinum Toxin A Versus Ethanol for Treatment of Patients With Benign Prostatic Hyperplasia
To compare safely and efficacy of intraprostatic injection of botulinum toxin A versus ethanol for treatment of benign prostatic hyperplasia (BPH).
- Conditions
- Male, Ultrasonography, Botulinum Toxins, Type A, Injection; Complications, Infection
- Trial name
- NCT03385161
- Testing
- Botulinum toxin A, Ethanol
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Prostate Cancer
Deformable Registration of Multi-parametric MRI to Intra-operative Transrectal Ultrasound for Prostate Brachytherapy
Objective: To focus the high dose radiation to the gross tumor in the prostate while maintaining adequate dose for control of microscopic disease elsewhere in the prostate.
- Trial name
- NCT02790216
- Testing
- Brachytherapy
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center
Prostate Cancer
Does End-fire Technique Increase Detection Rate of Prostate Cancer at First Re-biopsy Compared to Side-fire Technique?
Prostate cancer is the most common cancer among men in Sweden. During investigation of suspected cancer transrectal ultrasound with needle biopsies from prostate leeds to diagnosis.
- Trial name
- NCT02761135
- Where
- Sweden
- Volunteers
- 364 people
- Sponsor
- Kronoberg County Council
Infection, Prostatic Diseases
A Prospective Trial of Povidone-iodine Suppository Before Transrectal Ultrasound Guided Prostate Biopsy
To assess the effect of povidone-iodine on infectious complication rate caused by transrectal prostate biopsy
- Conditions
- Infection, Prostatic Diseases, Misadventure During Aspirating Needle Biopsy
- Trial name
- NCT02245334
- Testing
- Povidone-Iodine
- Where
- South Korea
- Volunteers
- 1,578 people
- Sponsor
- Seoul National University Hospital
Prostate Cancer
Prostate Volume Changes Following Prostate Brachytherapy With Iodine-125 Seeds
The size of the prostate changes due to insertion of the radioactive seeds. We will measure the prostate size, before and after the procedure.
- Trial name
- NCT00348465
- Testing
- Brachytherapy with Iodine-125 seeds
- Volunteers
- 29 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Prostate Biopsy, Post Biopsy Bleeding
Routine Probe Compression After Transrectal Prostate Biopsy(RPCAB) to Reduce Bleeding and Infectious Complications
Hematuria (up to 50%) and rectal bleeding (up to 30%) are common complications following transrectal ultrasound-guided prostate biopsy. Although most cases are mild, some require additional intervention.
- Conditions
- Prostate Biopsy, Post Biopsy Bleeding, Transrectal Ultrasound-guided Prostate Biopsy
- Trial name
- RPCAB (NCT07550985)
- Testing
- Probe compression
- Where
- South Korea
- Volunteers
- 324 people
- Sponsor
- Veterans Health Service Medical Center, Seoul, Korea
Prostate Cancer
Single-center Trial for the Validation of High-resolution Transrectal Ultrasound (Exact Imaging Scanner ExactVu) for the Detection of Prostate Cancer
The primary objective of this study is to evaluate the performance of HR-TRUS in detection of prostate cancer lesions relative to whole mount section after radical prostatectomy as the reference.
- Trial name
- EXACTVU (NCT03679819)
- Testing
- HR-TRUS
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Institut Paoli-Calmettes
Cellular Diagnosis, Prostate Cancer
ClariCore System Used in Transrectal Ultrasound Guided Prostate Biopsy for Real-Time Tissue Evaluation
The purpose of this study is to demonstrate the effectiveness and safety of the ClariCore System in obtaining prostate biopsies with device feedback that provides real-time tissue classification.
- Trial name
- SCORE (NCT03504761)
- Testing
- ClariCore Optical Biopsy System
- Where
- 6 sites in United States
- Volunteers
- 325 people
- Sponsor
- Precision Biopsy, Inc.
Prostate Neoplasm
PRostate Evaluation for Clinically Important Disease: Sampling Using Image-guidance Or Not?
This evaluates the detection rates of prostate cancer by MRI-targeted prostate biopsy compared to standard 12-core trans-rectal ultrasound guided (TRUS) prostate biopsy.
- Trial name
- PRECISION (NCT02380027)
- Testing
- MRI, MRI-targeted biopsy, TRUS-biopsy
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University College, London
Prostate Cancer
Quantification of Contrast Enhanced Ultrasound (CEUS) in the Detection of Prostate Cancer
With Contrast Enhanced UltraSound (CEUS) cancer induced neovascularisation can be visualised with the potential to improve ultrasound imaging for prostate cancer detection and localisation significantly.
- Trial name
- AMC_2011_190 (NCT01481441)
- Testing
- SonoVue
- Where
- Netherlands
- Volunteers
- 208 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)