Clinical trials: Transrectal Ultrasound
Prostate Cancer
Study on Triple Therapy Combined With HIFU for High-Tumor-Burden mHSPC
This study is a single-arm prospective cohort study designed to evaluate the efficacy and safety of triple therapy (ADT + darolutamide + docetaxel) combined with transrectal high-intensity focused ultrasound (HIFU) focal therapy…
- Trial name
- NCT07172685
- Testing
- Darolutamide , Docetaxel , ADT and Transrectal HIFU Focal Therapy
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Qilu Hospital of Shandong University
Locally Advanced Cervical Cancer, Brachytherapy
This is a Multicentre International Study Evaluating CT-based IGABT With / Without Either TRUS During BT/Pre BT MR as Per IBS-GECESTRO-ABS Recommendations for Target contouring-as an Alternative to MRIGABT for Cervical Cancer From Implementation Perspectives Under EMBRACE-III:TRIPLET IMPACT Study.
Title: Integration of Multi-modality Imaging Protocols with Emphasis on CT in Image-Guided Adaptive Brachytherapy (IGABT) for Cervical Cancer - EMBRACE III-TRIPLET : IMPACT Study Locally advanced cervical cancer (LACC) remains a…
- Conditions
- Locally Advanced Cervical Cancer, Brachytherapy, CT, Transrectal Ultrasound
- Trial name
- IMPACT (NCT07249021)
- Testing
- CT IGABT
- Where
- India
- Volunteers
- 1,200 people
- Sponsor
- Homi Bhabha Cancer Hospital & Research Centre
Prostate Cancer
Deformable Registration of Multi-parametric MRI to Intra-operative Transrectal Ultrasound for Prostate Brachytherapy
Objective: To focus the high dose radiation to the gross tumor in the prostate while maintaining adequate dose for control of microscopic disease elsewhere in the prostate.
- Trial name
- NCT02790216
- Testing
- Brachytherapy
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Sheba Medical Center
Anesthesia
Mixture Nitrous Oxide - Oxygen 50-50% in Transrectal Prostate Biopsy Guided by Ultrasound
Introduction: Transrectal ultrasound-guided prostate biopsy (TUPB) is the gold standard diagnostic tool for prostate cancer and, though may be well tolerated for some patients, about 65 to 90% of then still complain of…
- Trial name
- NCT02899182
- Testing
- Nitrous Oxide NO, O2
- Where
- Brazil
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Infertility Due to Azoospermia
Role of Transrectal-ultrasound in Evaluation of Azoospermia
Azoospermia is a word meaning to ejaculates with no spermatozoa without a definite underlying cause .1% of men has azoospermia, representing nearly 10 to 15% of all infertile men.
- Trial name
- NCT05026190
- Testing
- transrectal ultrasound
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cancer
Trial of Methoxyflurane With Periprostatic Local Anaesthesia to Reduce the Discomfort of TRUS B
A phase 3 double-blind placebo-controlled randomized trial of methoxyflurane with periprostatic local anaesthesia to reduce the discomfort of transrectal ultrasound-guided prostate biopsy (Pain-Free TRUS B).
- Trial name
- TRUSB (NCT02604225)
- Testing
- Methoxyflurane
- Where
- 7 sites in Australia, New Zealand
- Volunteers
- 420 people
- Sponsor
- University of Sydney
Transrectal Systematic Prostate Biopsy Related Pain
A Study on the Pain Control Effect of the Anesthetic Method During Prostate Biopsy: Comparison Between Pelvic Plexus Block and Periprosthetic Nerve Block
This study assesses differences in the effects of pelvic plexus block and periprostatic nerve block among various anesthetic methods that reduce the pain caused by prostate biopsy.
- Trial name
- NCT03681522
- Testing
- Pelvic plexus block, Periprostatic nerve block
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Prostate Cancer, Procedural Pain Relief
AcuTENS for Pain Relief During TRUS-Guided Prostate Biopsy
This study evaluates whether transcutaneous electrical nerve stimulation applied at specific acupuncture points (AcuTENS) can reduce pain and anxiety during transrectal ultrasound-guided prostate biopsy for participants suspected…
- Conditions
- Prostate Cancer, Procedural Pain Relief, TRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSY, Transcutaneous Electrical Nerve Stimulation
- Trial name
- NCT07292337
- Testing
- Active AcuTENS
- Where
- Malaysia
- Volunteers
- 53 people
- Sponsor
- University of Malaya
Prostate Cancer
Contrast Enhanced Transrectal Ultrasonography (TRUS) to Assess Prostatic Vascularity After Radiotherapy (XRT)
Solid tumors, including prostate cancer, commonly exhibit tumor-associated neovascularity (growth of new blood vessels to feed the tumor) with increased microvessel density.
- Trial name
- NCT00635167
- Testing
- Contrast Enhanced-Transrectal Ultrasound
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Prostate Biopsy
Effect of Virtual Reality Goggles on Anxiety, Comfort and Complications in Patients Undergoing Transrectal Ultrasound-guided Prostate Biopsy
This study was aimed to determine the effect of virtual reality goggles on anxiety, comfort and complication development in patients undergoing transrectal ultrasound-guided prostate biopsy in a randomized controlled experimental…
- Trial name
- NCT06959264
- Testing
- Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Tarsus University
Localized Prostate Cancer
Clinical Study of HIFU for Localized Prostate Cancer
In this study, the safety and effectiveness data of Sonablate system, a transrectal high-intensity focused ultrasound therapeutic instrument, in the treatment of localized prostate cancer were collected, and the treatment…
- Trial name
- HIFU (NCT06362577)
- Testing
- EQ-5D-5L IPSS IIEF-5 EPIC-26 ECOG
- Where
- China
- Volunteers
- 60 people
- Sponsor
- RenJi Hospital
Prostate Cancer
Single-center Trial for the Validation of High-resolution Transrectal Ultrasound (Exact Imaging Scanner ExactVu) for the Detection of Prostate Cancer
The primary objective of this study is to evaluate the performance of HR-TRUS in detection of prostate cancer lesions relative to whole mount section after radical prostatectomy as the reference.
- Trial name
- EXACTVU (NCT03679819)
- Testing
- HR-TRUS
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Institut Paoli-Calmettes
Prostate Cancer
Prostate Cancer Detection Rate of Targeted Biopsies With PCaVision
The primary objective is to demonstrate non-inferiority of the detection rate of clinically significant prostate cancer (csPCa) in targeted biopsies based on PCaVision imaging (PCaVision pathway) in comparison with the detection…
- Trial name
- NCT06281769
- Testing
- 3D multi-parametric ultrasound targeted biopsy pathway using PcaVision, MRI targeted biopsy pathway
- Where
- 5 sites in Netherlands
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Prostate Cancer
Intra-operative Trans-rectal Ultrasound Guidance for Robot-assisted Radical Prostatectomy
Radical prostatectomy, or the surgical extirpation of the prostate, is a standard treatment for prostate cancer. The state of the art radical prostatectomy involves a robotic laparoscopic surgery system (the da Vinci) which…
- Trial name
- TRUS-RP (NCT02001597)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of British Columbia
Anal Fistula, Rectal Fistula
Mechanical Bowel Preparation Prior To Sphincter-Sparing Surgery For Complex Anal Fistulae
The goal of this clinical trial is to learn whether bowel preparation with Plenvu before surgery improves healing of complex anal fistula in adults aged 18 to 64 years with a fistula of cryptoglandular origin or associated with…
- Conditions
- Anal Fistula, Rectal Fistula, Crohn Disease
- Trial name
- PLEN-SPARE (NCT07897539)
- Testing
- Mechanical bowel preparation
- Where
- Sweden
- Volunteers
- 116 people
- Sponsor
- Region Skane
Prostate Cancer
Trans-Rectal Ultrasound-Guided (TRUS) Adverse Events
The goal of this study is to identify any side effects caused by the implanting of markers via the rectum. The investigators will also try to determine if any other factors (such as the position of the markers) influence the risk…
- Trial name
- NCT00923416
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- University Health Network, Toronto
Pain
Intravenous Propofol and Fentanyl vs Propofol for Sedation in TRUS Biopsy
Nowadays, TRUS biopsy become one of the most popular tests for diagnosis of prostate cancer. This procedure causes pain to the patients who does not received the sedative drugs or analgesic drugs.
- Trial name
- NCT02733705
- Testing
- Control, Fentanyl, propofol
- Where
- Thailand
- Volunteers
- 124 people
- Sponsor
- Mahidol University
Infective Complications Post-transrectal Prostate Biopsy
Prostate Biopsy Antisepsis
During a prostate biopsy, a needle is guided through the rectum into the prostate. Although patients are given antibiotics before the biopsy, there is still a risk of bacteria getting from the rectum into the bladder, prostate…
- Trial name
- NCT00999427
- Testing
- Povidone-iodine
- Where
- 3 sites in Canada
- Volunteers
- 865 people
- Sponsor
- University of British Columbia
Urinary Tract Infections
Efficacy Study of Prophylaxis With Fosfomycin Versus Ciprofloxacin Prior Prostate Biopsy
The purpose of this clinical trial is compare the incidence of symptomatic or asymptomatic bacteriuria after transrectal ultrasound guided prostate biopsy using a single dose of fosfomycin 3 g one hour before the biopsy compared…
- Trial name
- BIPROST (NCT01803191)
- Testing
- Fosfomycin 3 g, Ciprofloxacin 500 mg
- Where
- 3 sites in Spain
- Volunteers
- 461 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Prostate Neoplasms, Prostate Biopsy
Effects of Music and Conversation in Prostate Biopsy
The goal of this observational study is to learn about the effects of music and conversation on pain and anxiety levels during Transrectal Ultrasound-Guided Prostate Biopsy.
- Trial name
- TRUS-BX (NCT07006779)
- Testing
- Music intervention, Conversation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bozok University