Clinical trials: Transthoracic Echocardiography
Right Ventricle, Speckle Tracking
Interchangeability of Right Ventricle Longitudinal Shortening in Echocardiography
RV longitudinal shortening fraction (RV-SLF) is based on the analysis of the tricuspid annulus displacement (TAD) and can be performed in transthoracic (TTE) or transoesophageal echocardiography (TEE).
- Conditions
- Right Ventricle, Speckle Tracking, Strains, Cardiac Surgery
- Trial name
- RVLSBO (NCT05404737)
- Testing
- transthoracic echocardiography (TTE), transoesophageal echocardiography (TEE).
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Type 2 Diabetes
Myocardial Perfusion in Type 2 Diabetes
The investigators aimed to evaluate microvascular circulation with novel method: real-time myocardial contrast echocardiography in patients with type 2 diabetes and normal coronary arteries.
- Trial name
- NCT01043965
- Testing
- Metformin
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Cardiac Catheterization, Blood Pressure
Noninvasive, Subharmonic Intra-Cardiac Pressure Measurement
The fundamental hypothesis of this project is that real-time intracardiac pressures can be monitored and quantified noninvasively in humans using a novel contrast-enhanced ultrasound technique called subharmonic-aided pressure…
- Conditions
- Cardiac Catheterization, Blood Pressure, Heart Ventricles, Echocardiography
- Trial name
- NCT03243942
- Testing
- Definity
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Thomas Jefferson University
Cardiac Diseases Requiring Surgery
Correlation of Estimated Continuous Cardiac Output (esCCO) and TEE in Pediatric Cardiac Surgery
The purpose of this study is to determine the measuring accuracy of the truly non-invasive method estimated continuous cardiac output (esCCO) against the reference method transesophageal echocardiography in pediatric cardiac…
- Trial name
- NCT01865994
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Heidelberg University
Acute Respiratory Distress Syndrome
Prediction of Outcomes With a Miniaturized Transesophageal Echocardiography Probe in Patients With Acute Respiratory Distress Syndrome
The Superior Vena cava Respiratory Collapse Index (cVCS) is a haemodynamic parameter measured exclusively by transoesophageal ultrasound (TEE), which is used to assess cardiac precharge-dependence status.
- Trial name
- PreMiTE-ARDS (NCT03763773)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Lille
Hypertrophic Cardiomyopathy
Comparison of Data Obtained by Echocardiography and Magnetic Resonance Imaging in Hypertrophic Cardiomyopathy
Compare data (structural and functional) obtained by transthoracic rest echocardiography and magnetic resonance imaging (with gadolinium) in 30 patients with hypertrophic cardiomyopathy
- Trial name
- NCT00315783
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypertrophic Cardiomyopathy (HCM)
Perfusion Abnormalities in Hypertrophic Cardiomyopathy
The purpose of this study is to investigate whether myocardial microvascular perfusion in patients with hypertrophic cardiomyopathy improved after initiation of cardiac myosin inhibitor therapy.
- Trial name
- NCT06599229
- Testing
- myocardial contrast echo
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Cardiac Output
Assessment of Cardiac Output With EtCO2
Hemodynamic monitoring, especially cardiac output assessment, is a key feature for the management of critically ill patients. Although the use of invasive methods, such as thermodilution with a pulmonary artery catheter, remains…
- Trial name
- COCO2 (NCT03524313)
- Testing
- End tidal carbon monoxide
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Subarachnoid Hemorrhage (SAH), Left Ventricular Dysfunction
Detection of Myocardial Dysfunction in Non-severe Subarachnoid Hemorrhage (WFNS 1-2) Using Speckle-tracking Echocardiography (STRAIN)
Subarachnoid hemorrhage (SAH) can cause transient myocardial dysfunction. Recently, it have been reported that myocardial dysfunctions that occur in SAH are associated with poor outcomes.
- Conditions
- Subarachnoid Hemorrhage (SAH), Left Ventricular Dysfunction, Stress Cardiomyopathy
- Trial name
- SAH-STRAIN (NCT03761654)
- Testing
- Global Longitudinal Strain measure
- Where
- France
- Volunteers
- 117 people
- Sponsor
- University Hospital, Bordeaux
Heart Failure, Pulmonary Vascular Disease
Contrast Echocardiography During Exercise to Assess Pulmonary Blood Volume
The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise.
- Trial name
- NCT06195059
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Mayo Clinic
Ultrasound
Human vs Machine: a RCT Comparing Traditional In-person Instruction, AI Versus VR for Learning Basic CCE
The aim of the study is to investigate if hands-on training for basic CCE with virtual reality simulators or guided by artificial intelligence is non-inferior to training by an experienced instructor.
- Trial name
- NCT06355557
- Testing
- AI enabled ultrasound system for self-directed learning, Simulator for self-directed learning, traditional with human instructors
- Where
- Singapore
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Cardiopulmonary Bypass
Cerebral Perfusion Monitoring With Transpharyngeal Ultrasonography
This prospective observational pilot study investigates transpharyngeal ultrasonography (TPU) as an additional neuromonitoring strategy to assess cerebral perfusion during on-pump cardiovascular surgery.
- Trial name
- TP-Echo (NCT01828411)
- Testing
- Transpharyngeal ultrasonography, Duplex sonography
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Atrial Septal Defect (ASD), Dexmedetomidine
Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect
The aim of this randomized trial is to determine efficacy of dexmedetomidine in improving quality of recovery in pediatric patients undergoing interventional catheter closure of ASD while maintaining the hemodynamic parameters.
- Conditions
- Atrial Septal Defect (ASD), Dexmedetomidine, Delirium - Postoperative, Stress Response
- Trial name
- NCT06631534
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Chagas Disease
New Tools for the Diagnosis, Prognosis and Treatment Follow-up in Chagas Disease
Chagas disease is endemic to Latin America, and is of emerging importance in non-endemic countries because migration of people infected with T. cruzi. Current methods for diagnosis of T. cruzi infection are not ideal.
- Trial name
- BIOMARCHA (NCT01755377)
- Testing
- Benznidazole
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Barcelona Centre for International Health Research
Echocardiography, Stress, COVID-19
Stress Echocardiography in Patients Recovery From Mild COVID-19 Illness
With the appearance of the new SARS-COV2 virus, additional challenges are being imposed on the medical community after the resolution of acute COVID-19 illness, resulting in specific pathophysiologic mechanisms that while acutely…
- Conditions
- Echocardiography, Stress, COVID-19, Hypertension, Pulmonary
- Trial name
- ECHO-vid (NCT04498299)
- Testing
- echocardiogram 2D
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Miguel Ayala León
To Assess Cardiovascular Function
QuantaFlo HD Clinical Validation Study
The primary aim of this validation protocol is to assess cardiovascular function through transthoracic echocardiography ("Echo") measurements and the QuantaFlo HD test measuring blood flow at the finger during a forced expiration…
- Trial name
- NCT07219693
- Testing
- QuantaFlo HD
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Semler Scientific
Echocardiography
GE CVUS Device Evaluation
The purpose of the study is to collect user feedback on the Vivid E95 ultrasound system and probes during clinical procedures on the device's intended population in order to optimize the device.
- Trial name
- NCT05340244
- Testing
- Investigational ultrasound exam
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- GE Healthcare
Portal Hypertension, Liver Diseases
Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment
Liver cirrhosis is a chronic disease characterized by a progressive accumulation of fibrosis, loss of liver function and portal hypertension leading to several hemodynamic changes.The exact pathophysiological mechanisms causing…
- Conditions
- Portal Hypertension, Liver Diseases, Liver Cirrhoses, Cirrhosis
- Trial name
- NCT03443934
- Where
- Denmark
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Cardiovascular Risk Stratification, Carotid Intima-media Thickness (CIMT)
CIMT and Plaque Assessment Findings in Subjects Undergoing Stress Echocardiography For Risk Stratification
The purpose of this research study is to determine if carotid artery ultrasound scanning can provide additional information for determining cardiovascular risk in patients.
- Conditions
- Cardiovascular Risk Stratification, Carotid Intima-media Thickness (CIMT), Stress Echocardiography (SE)
- Trial name
- NCT02245048
- Testing
- Carotid Intima-Media Thickness (CIMT)
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Mayo Clinic
Ventricular Function
Assessment of Right Ventricular Volume in Pediatric Patients
Most publication are basing RV volumes on images acquired from the apical window. However, some data have called the practice of basing these images on apical window into question.
- Trial name
- NCT04099810
- Testing
- three-dimensional echocardiography
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
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