Clinical trials: Transtibial Amputation
Amputation
Transtibial Pin Lock Suspension at Varying Distraction Values Using a Modified Air Bladder Casting System
To assess the effects various distraction values have on the 'slippage' effect of a transtibial pin-lock system
- Trial name
- NCT04248907
- Testing
- 0 pound tension, 2 pound tension, 4 pound tension
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Loma Linda University
Amputation
Reduction of Shear Forces Using Semi-flexible Sockets on Transtibial Amputees
The purpose of this graduate student research study, is to test two different sockets for comfort and test what pressures are created by the socket during daily activities.
- Trial name
- NCT03390153
- Testing
- semi flexible socket, rigid fiber socket
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Amputation
Measures of Gait Efficiency of Three Multi-Axial, Vertical Shock and Energy Storing-Return Prosthetic Feet During Simple & Complex Mobility Activities
Many service members suffering major limb amputation(s) during active duty seek to return to active duty. The purpose of this study is to determine if biomechanic and/or bioenergtic differences exist between popular…
- Trial name
- NCT01404559
- Testing
- Ossur Variflex prosthetic foot, Ossur Ceterus prosthetic foot, Endolite Elite Blade prosthetic foot
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Amputation, EMG
The Dynamic Postural Changes in Transtibial and Transfemoral Amputees
This research was planned to examine how unpredictable movements on the support surface will affect muscle activation and kinematic parameters in individuals with transtibial and transfemoral amputations.
- Conditions
- Amputation, EMG, Balance, Perturbation
- Trial name
- NCT05301270
- Testing
- EMG Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Amputation Stump
Computational Design, Fabrication, and Evaluation of Optimized Patient-Specific Transtibial Prosthetic Sockets
The overall goal of this study is to further develop and clinically assess a computational and data-driven design and manufacturing framework for mechanical interfaces that quantitatively produces transtibial prosthetic sockets…
- Trial name
- NCT03544853
- Testing
- Prosthetic socket for transtibial amputee
- Where
- 2 sites in United States, Mexico
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Dual Task, Amputation
Comparison of Dual Task Gait Characteristics in Individuals With Amputation and Healty Individuals
In amputee, dual task has been found to cause a decrease in walking speed. However, there is no study of how gait characteristics are affected when the speed does not change.
- Conditions
- Dual Task, Amputation, Gait
- Trial name
- NCT04392466
- Testing
- walking on the treadmill
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Lower Limb Amputation, Older Adults
Study of WiiFit to Enhance Walking in Older Adult Amputees
WiiNWALK is a 4 week physical activity, with the intervention of a WiiFit, targeted to improve walking capacity in individuals with either a unilateral below-knee or above-knee amputation.
- Trial name
- WiiNWalk (NCT01942798)
- Testing
- Nintendo Wii, Wii Big Brain Academy Degree program
- Where
- 5 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Amputees
Physical Activity in Adults With Amputation
This cross-sectional study explores physical activity and energy expenditure among inactive adults with a unilateral transtibial amputation.
- Trial name
- NCT03722797
- Testing
- Metabolic Cost Testing Procedures
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Amputation
Agonist-Antagonist Myoneural Interface for Functional Limb Restoration After Transtibial Amputation
This study involves the functional testing of a new lower extremity prosthesis by healthy, active participants with fully healed transtibial (below knee) amputations.
- Trial name
- NCT03913273
- Testing
- AMI transtibial amputation, Standard transtibial amputation
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Traumatic Amputation of Lower Extremity
A Comparison of External Mechanical Work Between Different Prosthetic Feet
Recent dysvascular and diabetic amputees as well as older, long-term traumatic amputees are at risk of functional decline, joint degeneration, skin breakdown and further limb loss due to the forces placed on the contralateral…
- Trial name
- SEW (NCT01340807)
- Testing
- Specialized Functional Prosthetic Training
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Miami VA Healthcare System
Transtibial Amputation, Transfemoral Amputation
Improving Socket Fit in Female and Male Veterans With Transtibial and Transfemoral Amputation
The investigators do not yet know how a prosthetic socket with adjustable panels affects the performance of people with a lower limb amputation compared to a conventional prosthetic socket.
- Trial name
- SocketFit (NCT05989243)
- Testing
- Conventional prosthetic socket, Adjustable Quatro socket
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Phantom Limb, Motor Activity
The Effects of Targeted Phantom Motor Execution on Phantom Limb Control
Lower limb amputations account for more than 85% of all amputations. In Canada, it has been reported that transtibial amputation (TTA) is the most common level of amputation.
- Conditions
- Phantom Limb, Motor Activity, Amputation Stump, Amputation
- Trial name
- NCT05247827
- Testing
- Targeted phantom limb motor execution (exercise)
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Amputation, Elderly
Falls in Older Persons With Limb Loss
Lower limb prosthesis users are known to be at a substantially increased fall risk compared to able-bodied individuals. The interaction between increased fall risk, reduced balance confidence and high prevalence of a fear of…
- Trial name
- FOPLL (NCT03670004)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Amputation
Does Walking Performance Improve When Veterans With Leg Amputations Are Given Visual Feedback?
Previous studies suggest that Veterans with below the knee amputation using passive-elastic or powered prostheses have impaired physical function, which could increase the risk of osteoarthritis, leg/back pain, and…
- Trial name
- NCT03974945
- Testing
- Passive-elastic prosthetic foot, Powered ankle-foot prosthesis
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Amputation, Traumatic
Rectus Femoris Thickness Measurement in Unilateral Transtibial Amputated Prosthesis Users
Knee extension strengthening is one of the cornerstones of rehabilitation in prosthesis users with transtibial amputation. It is recommended in terms of increasing functional mobility, preventing the risk of fall and knee…
- Trial name
- NCT04262297
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Transfemoral Amputation, Transtibial Amputation
Mobile Device Outcomes-based Rehabilitation Program
This joint research project between the Department of Veterans Affairs (VA) and Department of Defense (DoD) will demonstrate that the implementation of the Mobile Device Outcomes-based Rehabilitation Program (MDORP) will improve…
- Trial name
- MDORP (NCT02891707)
- Testing
- Rehabilitative Lower-limb Orthopedic Accommodating-feedback Device (ReLOAD)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Lower Limb Amputation Below Knee (Injury)
The Effects of Small Variations in Shoe Heel Height on Gait in People With a Transtibial Amputation
Prosthetic alignment is important for walking function and walking comfort in people with a transtibial amputation (TTA). Prosthetic alignment is defined as the position of prosthetic parts relative to the body and to each other.
- Trial name
- NCT04641845
- Testing
- Cork inlay wedge
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Sint Maartenskliniek
Virtual Reality
Effects of Virtual Reality on Transtibial Amputation Physiotherapy Outcomes
The aim of this study is to compare the effects of virtual reality applications on quality of life, performance, balance, prosthesis adaptation and gait parameters in individuals with transtibial amputation.
- Trial name
- NCT03872193
- Testing
- Exercise
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Amputation
Optimizing Prosthetic and Bicycle Fit for Veterans With Transtibial Amputations
Bicycling is a promising form of low-impact exercise that could prevent/treat Type 2 diabetes. However, Veterans with transtibial amputations (TTAs) may not effectively utilize bicycling for rehabilitation and exercise due to…
- Trial name
- BestBikeFit (NCT03828331)
- Testing
- Prosthetic/Bicycle Configuration
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Lower Limb Amputation
Transtibial Amputee Balance Training: A Randomised Controlled Trial
Lower limb amputees have reduced joint mobility and strength which negatively influence an individual's ability to maintain balance.
- Trial name
- NCT02572011
- Testing
- Home-based Games Console Balance Training
- Where
- 2 sites in United Kingdom
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University