Clinical trials: Transurethral Resection of Bladder Tumor
Bladder Cancer
Comparison Study of Narrow Band Imaging Versus White Light Resection in Patients With Bladder Tumors/Cancer
The purpose of this study is to compare the recurrence rate at 1 year following Narrow Band Imaging and trans-urethral resection of bladder tumor with White Light and TURB in patients with non-muscle invasive bladder cancer.
- Trial name
- NCT01180478
- Testing
- White Light, Narrow Band Imaging
- Volunteers
- 965 people
- Sponsor
- Clinical Research Office of the Endourological Society
Bladder Cancer, Non-Muscle-Invasive Bladder Cancer (NMIBC)
Active Surveillance Versus Adjuvant Intravesical Chemotherapy in Liquid Biopsy-Defined Low-Shedding Intermediate-Risk NMIBC
This study will evaluate whether adjuvant intravesical chemotherapy can be safely omitted under active surveillance after complete transurethral resection in selected patients with EAU intermediate-risk non-muscle-invasive…
- Trial name
- NCT07749924
- Testing
- Active Surveillance, Adjuvant Intravesical Chemotherapy
- Where
- 5 sites in China
- Volunteers
- 670 people
- Sponsor
- Tianjin Medical University Second Hospital
Urinary Bladder Cancer
Intravesical Gem/Doce in Patients With NMIBC
Intravesical immunotherapy or chemotherapy for non-muscle invasive bladder cancer (NMIBC) is a well-established treatment for preventing or delaying tumor recurrence after tumor resection.
- Trial name
- NCT05644041
- Testing
- gemcitabine + docetaxel
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Arizona
Bladder Cancer
Comprehensive Multiparametric Magnetic Resonance Imaging After Transurethral Resection of Non Muscle-invasive Bladder Tumor; Can it Replace Second Look Biopsy? A Prospective Study
The aim of the study is to prospectively assess the role of mpMRI as a non invasive method for assessment of possible residual tumor after initial resection of non muscle invasive bladder tumor.
- Trial name
- NCT03914001
- Testing
- mpMRI, Second look TURBT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Bladder Cancer
Thulium Fiber Laser En-bloc Resection vs Conventional Transurethral Resection of Non-muscle-invasive Bladder Cancer
Ongoing efforts aim at overcoming the challenges of conventional transurethral resection of bladder tumor (TURBT) such as the high recurrence rate, difficulty of pathologic interpretation and complications including wall injury.
- Trial name
- NCT04110483
- Testing
- Thulium fiber laser en-bloc resection of non-muscle-invasive bladder cancer, Transurethral resection of non-muscle-invasive bladder cancer
- Where
- Russia
- Volunteers
- 130 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Bladder Cancer
Chemotherapy With or Without Surgery in Treating Patients With Bladder Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Infusing chemotherapy drugs directly into the bladder may kill more cancer cells.
- Trial name
- NCT00042887
- Testing
- mitomycin C, conventional surgery
- Where
- 12 sites in Belgium, Italy and 3 more
- Volunteers
- 58 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Urinary Bladder Neoplasms
TURBt With Adjuvant Cryoablation to Treat Bladder Cancer
The purpose of this study is to evaluate the safety and efficacy of applying cryoablation as an adjuvant therapy with TUR to treat bladder tumor.
- Trial name
- NCT02760953
- Testing
- Cryoablation, Epirubicin
- Volunteers
- 150 people
- Sponsor
- Huashan Hospital
Urinary Bladder Cancer
Role of MRI in Assessment of the Urinary Bladder Wall Post Transurethral Tumor Resection
To study the feasibility of using magnetic resonance imaging (MRI) in evaluation UB wall thickening after transurethral resection (TUR) of bladder cancer.
- Trial name
- NCT05787938
- Testing
- MRI
- Volunteers
- 58 people
- Sponsor
- Assiut University
High-Grade Early-Stage Bladder Cancer
VA Randomized Trial of Surveillance Intervals After Transurethral Resection of High Grade Bladder Tumors
CSP #2036 is a pragmatic, randomized, intent-to-treat, two-arm, parallel, multicenter CSP trial. Blinding of clinical staff and participants will not be possible.
- Trial name
- VATSIT (NCT07408830)
- Testing
- Low Intensity Surveillance, High Intensity Surveillance
- Where
- United States
- Volunteers
- 2,482 people
- Sponsor
- VA Office of Research and Development
Bladder Cancer
Loop Resectoscope in Treating Patients With Bladder Cancer or Benign Prostatic Hyperplasia Who Are Undergoing Transurethral Resection
RATIONALE: Transurethral resection is a less invasive type of surgery for bladder cancer or benign prostatic hyperplasia. Transurethral resection using a loop resectoscope may have fewer side effects and improve recovery.
- Trial name
- NCT00303654
- Testing
- biopsy, therapeutic conventional surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Roei Medical Technologies Ltd.
Hematuria, Retention, Urinary
Anticoagulant/Antiaggregant Use and Postoperative Bleeding Risk in Patients With Bladder Tumor and Benign Prostatic Hyperplasia
Patients who were using anticoagulant or antiaggregant medications for any reason and underwent transurethral resection of bladder tumor (TUR-BT) or transurethral resection of the prostate (TURP) or open prostatectomy (OP) due to…
- Conditions
- Hematuria, Retention, Urinary, Operative Bleeding, Blood Transfusion Complication
- Trial name
- NCT05314582
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Bezmialem Vakif University
Bladder Disease
Multi Center Study to Obtain Bladder Tissue Specimens From Patients Undergoing Transurethral Resection Biopsy Procedure
The objective of the study is to obtain bladder tissue specimens from patients otherwise undergoing cystoscopy for use in research at Tengion, Inc.
- Trial name
- NCT00615043
- Testing
- Bladder biopsy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Tengion
Bladder Cancer
Complications of Transurethral Resection of the Bladder Tumour
This is a prospective study enrolling consecutive patients who undergo transurethral resection of the bladder tumour (TURBT) aimed at determination of a safety of the procedure.
- Trial name
- ComTUR (NCT03029663)
- Testing
- Transurethral resection of the bladder tumour
- Where
- Poland
- Volunteers
- 983 people
- Sponsor
- Medical University of Warsaw
Neuromuscular Blockade
Neuromuscular Blockade During Transurethral Resection of Bladder Cancer
Transurethral resection of the bladder tumor (TURB) for bladder tumor excision is the mainstream treatment. However, the beneficial effects of sugammadex after general anesthesia for TURB have not been thoroughly evaluated.
- Trial name
- NCT03039543
- Testing
- Rocuronium, Sugammadex
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Bundang Hospital
Bladder Cancer
3-Dimensional Conformal Radiation Therapy in Treating Patients With Bladder Cancer Who Have Undergone Transurethral Resection of the Bladder
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal…
- Trial name
- NCT01124682
- Testing
- diagnostic cystoscopy, diffusion-weighted magnetic resonance imaging, implanted fiducial-based imaging
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Bladder Cancer
Recurrence of Bladder Cancer After Transurethral Resection With Hexvix
This is a randomised, comparative, multicentre study to determine if the early recurrence rate of intermediate-risk bladder cancer is similar in subjects treated with multiple instillations of mitomycin C after resection…
- Trial name
- NCT00785694
- Testing
- hexaminolevulinate
- Where
- France
- Sponsor
- GE Healthcare
Non-muscle Invasive Bladder Cancer (NMIBC), Bladder Tumor (TURBT)
Continuous Bladder Irrigation Following Transurethral Resection of Bladder Tumors
The purpose of this pilot study is to determine if washing out the bladder with large volumes of saline after surgical removal of bladder tumors helps to decrease the number of loose cells floating within the bladder after…
- Trial name
- NCT03839472
- Testing
- CBI
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Bladder Cancer
Surgery With or Without Chemotherapy in Treating Patients With Newly Diagnosed or Recurrent Bladder Cancer
RATIONALE: Transurethral resection is a less invasive type of surgery for bladder cancer and may have fewer side effects and improve recovery.
- Trial name
- NCT00003725
- Testing
- valrubicin, conventional surgery
- Where
- 53 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- Anthra Pharmaceuticals
Urinary Bladder Tumor
Clinical Trial Using Bipolar Technology for Transurethral Resection of Bladder Tumor
Bladder cancer is a common urological malignant disease. Patients with bladder cancer will first be managed with transurethral resection (TUR) of bladder tumor.
- Trial name
- NCT01581723
- Testing
- Monopolar diathermy, Bipolar diathermy
- Where
- 2 sites in Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong