Clinical trials: Trauma, completed
Pain, Postoperative, Trauma
Reducing Pain and Anxiety During Dressing Changes After Burn Surgery Using Virtual Reality
Burn injury and its treatment is an intensely painful experience. Most severely injured patients require numerous dressing changes and skin grafting procedures (removing skin from healthy part of the body and moving it to damaged…
- Conditions
- Pain, Postoperative, Trauma, Burns
- Trial name
- BURN-360 (NCT04820400)
- Testing
- Immersive VR Video
- Where
- Canada
- Volunteers
- 82 people
- Sponsor
- Sunnybrook Health Sciences Centre
Stroke, Subarachnoid Hemorrhage
MUSic Therapy In Complex Specialist Neurorehabilitation
Aim: Investigate whether patients undergoing specialist rehabilitation after complex neurological injury show different functional outcomes if music therapy is included in their rehabilitation program compared to usual care.
- Conditions
- Stroke, Subarachnoid Hemorrhage, Traumatic Brain Injury, Tumor, Brain
- Trial name
- MUSICS (NCT05777499)
- Testing
- Music Therapy, Control Therapy
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University College, London
Depression, Anxiety
Description of the Lived Experiences of Family Caregivers for People With Mental Health Comorbidities
Mental health problems such as depression, trauma and anxiety are common in low-resource contexts, such as Zambia. Comorbidity, or having multiple mental health problems, is the norm.
- Conditions
- Depression, Anxiety, Trauma
- Trial name
- MCE (NCT07760701)
- Where
- Zambia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre for Infectious Disease Research in Zambia
Neurological Conditions, Brain Diseases
NEO-REEDUC - Mixed Reality for Motor Rehabilitation: a Prospective, Multicenter, Controlled, Randomized, Open Study.
This study aims to assess the effectiveness of a motor rehabilitation protocol that includes mixed reality activities, compared to conventional rehabilitation, on postural stability in children and adult patients with…
- Conditions
- Neurological Conditions, Brain Diseases, Cerebral Palsy, Parkinson Disease (PD)
- Trial name
- NCT07063810
- Testing
- Mixed Reality Rehabilitation
- Where
- 5 sites in France
- Volunteers
- 76 people
- Sponsor
- Slb Pharma
Trauma, Hemorrhage
Transfusion for Major Haemorrhage in Trauma - Characteristics and Outcomes
Background: Trauma is the leading cause of death in young adults worldwide and the most common causes of mortality are haemorrhage and brain injury.
- Conditions
- Trauma, Hemorrhage, Shock, Traumatic, Acute Coagulopathy
- Trial name
- NCT05573841
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Karolinska University Hospital
Transfusion Adverse Reaction, Major Trauma
Blood Storage Related Mortality and Adverse Effects in Trauma Patients
The purpose of this retrospective study is to examine the following factors related to blood storage time in severely injured trauma patients who received large blood transfusions: 1.
- Conditions
- Transfusion Adverse Reaction, Major Trauma, Blood Product Transfusion for All Conditions
- Trial name
- NCT07341139
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Kocaeli City Hospital
Maxillofacial Trauma
Early Versus Late Intervention in Maxillofacial Trauma
Maxillofacial trauma represents a significant clinical challenge requiring timely surgical management. This prospective study aims to compare early versus delayed intervention in patients with maxillofacial trauma and evaluate…
- Trial name
- NCT07749729
- Testing
- Timing of Open Reduction and Internal Fixation (ORIF)
- Where
- 2 sites in Yemen
- Volunteers
- 50 people
- Sponsor
- Haifa Mohammed Sharaf-Aldeen
Vertebral Compression Fracture, Spinal Trauma
VertebrOpLasty Versus Conservative Treatment in Acute Non Osteoporotic Vertebral Fractures
The purpose of this protocol is to prove the efficacy of vertebroplasty in patients suffering from acute non osteoporotic vertebral compression fracture.
- Trial name
- VOLCANO (NCT01643395)
- Testing
- vertebroplasty, conservative therapy
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Clermont-Ferrand
Perineal Trauma, Episiotomy
Effect of Boric Acid Wet Dressing on Postpartum Perineal Healing and Pain
Perineal trauma, including episiotomy and first- or second-degree perineal tears, is a common postpartum condition associated with pain and delayed wound healing after vaginal birth.
- Conditions
- Perineal Trauma, Episiotomy, Episiotomy Wound, Perineal Pain
- Trial name
- NCT07748182
- Testing
- 2% Boric Acid Wet Dressing, 0.9% Normal Saline Wet Dressing, Routine Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Saglik Bilimleri Universitesi
Spinal Cord Injuries, Polytrauma
Reduction of Opioid Dose Using Conditioning & Open-Label Placebo (COLP) in Intensive Rehabilitation
The use of conditioning open-label placebo (COLP) will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury.
- Conditions
- Spinal Cord Injuries, Polytrauma, Burn Injury, Pain Management
- Trial name
- COLP (NCT03906721)
- Testing
- Oxycodone, Essential Oil
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Trauma, Vascular System Injury
Humacyte Acellular Tissue Engineered Vessel (ATEV) in Patients With Vascular Trauma
This study evaluates the use of the Acellular Tissue Engineered Vessel (ATEV) in adults with vascular trauma below the neck who are undergoing vascular reconstructive surgery.
- Trial name
- NCT03005418
- Testing
- Acellular Tissue Engineered Vessel (ATEV)
- Where
- 29 sites in United States, Israel
- Volunteers
- 72 people
- Sponsor
- Humacyte, Inc.
Trauma Injury
ICG Fluorescence Imaging in Open Fracture Trauma Patients
This is a prospective observational study that will evaluate the association between bone and tissue perfusion, as measured by indocyanine green (ICG) fluorescence imaging, and complications, in an effort to develop ICG…
- Trial name
- NCT04416412
- Testing
- Immunofluorescence Imaging
- Where
- 4 sites in United States
- Volunteers
- 124 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Posttraumatic Stress Disorder (PTSD), Trauma and Stressor Related Disorders
EMDR Group Therapy for Posttraumatic Stress Symptoms in Migrants
The goal of this randomized controlled trial is to evaluate the effectiveness and feasibility of the Eye Movement Desensitization and Reprocessing Integrative Group Treatment Protocol for Ongoing Traumatic Stress (EMDR-IGTP-OTS)…
- Conditions
- Posttraumatic Stress Disorder (PTSD), Trauma and Stressor Related Disorders, Psychological Distress
- Trial name
- NCT07731906
- Testing
- Integrative Group Treatment Protocol for Ongoing Traumatic Stress (EMDR-IGTP-OTS)
- Where
- Italy
- Volunteers
- 185 people
- Sponsor
- Azienda Sanitaria Locale Salerno
Trauma, PTSD
Key Dimensions of PTSD and ED
This study will test whether endothelial dysfunction could be the early subclinical mechanism by which posttraumatic stress disorder (PTSD) increases cardiovascular disease (CVD) risk, and whether posttraumatic fear-a key…
- Conditions
- Trauma, PTSD, Endothelial Dysfunction
- Trial name
- NCT03778307
- Testing
- Psychophysiological fear conditioning and extinction task, Eyetracking task
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- University of California, Los Angeles
PTSD, Trauma
Neuroendocrine Risk for PTSD in Women
This study will test for effects of estradiol (E2) on PTSD symptoms and functional magnetic resonance imaging (fMRI) indicators of stress vulnerability, in naturally-cycling women who are not using hormonal birth control.
- Trial name
- NCT03973229
- Testing
- Estradiol patch
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Emory University
Perineal Trauma, Ritgen Maneuver
Ritgen Maneuver and Birth-Related Perineal Trauma: RCT
Perineal trauma is one of the common complications that may occur during the second stage of labor and can negatively affect women's postpartum recovery and quality of life.
- Trial name
- NCT07713173
- Testing
- Ritgen maneuver, Routine Care Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medipol University
Major Trauma
Enhanced Rehabilitation After Major Trauma (PROPERLY)
The goal of this study is to assess the feasibility of recruitment, and barriers to delivery of an enhanced rehabilitation service, in patients surviving major trauma.
- Trial name
- PROPERLY (NCT05652790)
- Testing
- Enhanced Rehabilitation Programme, Standard Care
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Manchester University NHS Foundation Trust
Trauma and Stress Related Disorders, Grief (Traumatic Grief and Existential Grief)
P-CRP for Recent-Onset Severe Trauma
The purpose of this retrospective study was to evaluate the effectiveness of a new psychotherapy technique called Psychological Cognitive Reprocessing Procedure (P-CRP) in treating trauma symptoms.
- Conditions
- Trauma and Stress Related Disorders, Grief (Traumatic Grief and Existential Grief), Stress Disorder - Post-traumatic (Acute)
- Trial name
- P-CRP (NCT07360990)
- Testing
- Psychological-cognitive reprocessing procedure (P-CRP)., Expressive Narrative and Symbolic Drawing (ENSD)
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Zahide Betül Baydar
Head Injury, Sport Injury
Dynamic Vision Testing and Concussion Management
The purpose of this study is to determine the value of including dynamic vision testing into California State University, Northridge (CSUN) Athletics' established concussion protocol.
- Conditions
- Head Injury, Sport Injury, Concussion, Brain
- Trial name
- NCT04837066
- Testing
- Dynamic Vision Testing (Bertec Vision Advantage System) and Balance Error Scoring System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- California State University, Northridge
Trauma
Multicentre Study: Adherence to the Severe Trauma Patients Pathway in PACA Region
Trauma patient management concerns more than 140,000 patients per year in France. PACA Regional Emergency Observatory (ORU) has issued recommendations to optimize the management of these trauma patients from pre-hospital phase to…
- Trial name
- FILTRAUMA-PACA (NCT05401487)
- Testing
- Pre-hospital and hospital care
- Where
- 3 sites in France
- Volunteers
- 265 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer