Clinical trials: Trauma Abdomen
Surgical Site Infection, Surgery--Complications
Prophylaxis of Surgical Wound Infection With Topical Antibiotics
Surgical site infection (SSI) is the main complication of surgery. The prevention of superficial SSI by topical prophylaxis is controversial.
- Conditions
- Surgical Site Infection, Surgery--Complications, Colorectal Surgery, Cesarean Section; Infection
- Trial name
- NCT04476212
- Testing
- Topical antibiotic prophylaxis
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Hospital de Granollers
Surgical Site Infection, Cesarean Section; Infection
Abdominal Closure Bundle to Reduce Surgical Site Infection in Patients Undergoing C-sections. Cesarean Section Lead to Reduction in Surgical Site Infection? - A Randomized Controlled Trial
This study is a single center, randomized controlled trial investigating the use of an abdominal closure bundle to reduce surgical site infection in patients undergoing cesarean section.
- Trial name
- NCT03500055
- Testing
- Abdominal Closure Bundle
- Where
- United States
- Volunteers
- 850 people
- Sponsor
- Abington Memorial Hospital
Abdominal Reconstruction
A Comparison of Incisional Negative-Pressure Wound Therapy Versus Conventional Dressings Following Abdominal Surgery
The purpose of this study is to compare outcomes between incisional negative-pressure wound vacuum-assisted closure (VAC) therapy versus conventional dressings following abdominal surgery.
- Trial name
- NCT02534116
- Testing
- Vacuum-assisted closure (VAC) therapy, Gauze dressing
- Where
- United States
- Sponsor
- Yale University
Abdominal Trauma
Challenges in Management of Abdominal Trauma in Sohag University Hospital A Prospective Study
The present study will be conducted to evaluate the different patterns of abdominal trauma patients and their management in the Emergency Department of Sohag University Hospital
- Trial name
- NCT05805852
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Sohag University
Pain
Postoperative Analgesic Effect Of Dexmedetomidine Administration in Wound Infiltration for Total Abdominal Hysterectomy
The aim of this study was to investigate the analgesic efficacy of dexmedetomidine administration in wound infiltration for total abdominal hysterectomy.
- Trial name
- NCT01929252
- Testing
- Dexmedetomidine, Levobupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Acute Kidney Injury, Pneumoperitoneum
The Effect of Pneumoperitoneum (Raised Pressure in the Peritoneal Cavity) During Robotic Kidney/Prostate Cancer Surgery.
Within all the surgical specialties, major surgeries are performed whenever possible, as minimally invasive procedures to reduce blood loss, reduce pain and discomfort after surgery, avoid major scars, provide a faster recovery…
- Conditions
- Acute Kidney Injury, Pneumoperitoneum, Kidney
- Trial name
- NCT04755452
- Testing
- Low intra-abdominal pressure, High (standard) intra-abdominal pressure
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aalborg University Hospital
Mitochondrial Oxygenation Measurement, Surgical Site Infection
Anaesthetic Management Guided by COMET Measurements
Surgical site infection (SSI) is a significant cause of morbidity and mortality, prolonged hospital stays and healthcare costs. Perioperative low tissue oxygen tension is associated with a high risk of SSI.
- Trial name
- AIMED COMET (NCT05841576)
- Testing
- COMET monitoring device
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Rick Hulskes
Abdominal Aortic Aneurism, Surgery
Study of the Glycocalyx in Abdominal Aortic Aneurysm
The investigators want to measure the degradation of the endothelial glycocalyx before and after clamping the aorta, in patients operated for a abdominal aortic aneurism.
- Conditions
- Abdominal Aortic Aneurism, Surgery, Ischemic Reperfusion Injury
- Trial name
- Endo_eAAA (NCT01834092)
- Testing
- Plasma
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Surgical Wound
Blood Characteristics and Abdominal Emergency Surgery
After surgical tissue damage, cellular blood components are involved in tissue repair processes, yet their preoperative characteristics are not considered in routine clinical practice.
- Trial name
- NCT06028854
- Where
- 2 sites in Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Chile
Wound Dehiscence
Burst Abdomen in Emergency Midline Laparotomy: Incidence and Risk
The study was conducted in 250 patients who underwent midline Laparotomy at Kasr Al-Ainy emergency department, Cairo University from August 2017 until March 2018.
- Trial name
- NCT03684902
- Testing
- emergency midline exploratory laparotomy
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Cairo University
Diastasis, Muscle
Effect of Four Exercises on the Inter-recti Distance in Women
Diastasis rectus abdominis (DRA) is defined as an excessive separation between the two abdominal rectus muscles. It is generally quantified by the inter-recti distance.
- Trial name
- Traecho (NCT04501302)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- APOR B de Gasquet
Appendicitis
Wound Healing After Emergency Appendicectomy
The purpose of this trial is to compare two techniques of wound closure in open appendicectomies in adult patients: continuous, absorbable, intradermal suture and interrupted, non-absorbable sutures.
- Trial name
- NCT00913445
- Testing
- appendicectomy
- Where
- Finland
- Volunteers
- 200 people
- Sponsor
- Tampere University Hospital
Abdominal Surgery, Thoracic Surgery
Collecting Interval Timed Incisional Epidermal and Dermal Tissue Samples During Surgical Procedures to Profile Temporal Response of Tissue After Noxious Stimuli
Background: Opioids are a class of drug that are often used to manage pain after a person has surgery. Because of the current opioid crisis, researchers want to improve ways to manage pain after surgery with fewer side effects.
- Conditions
- Abdominal Surgery, Thoracic Surgery, Urological Surgery
- Trial name
- NCT04224870
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Abdominal Injuries
Hypertonic Saline Resuscitation in Trauma Patients After Hemorrhage Control
This study aimed to determine whether hypertonic saline solution is effective in the resuscitation of injured patients undergoing abdominal damage control surgery regarding early closure of the abdominal wall.
- Trial name
- CELTA (NCT02542241)
- Testing
- Sodium Chloride [3%], Sodium Chloride [0.9%]
- Where
- Colombia
- Volunteers
- 52 people
- Sponsor
- Fundacion Clinica Valle del Lili
Severe Traumatic Brain Injury, Pancreatic Diseases
The Effect of Closed Suction System on the Incidence of Ventilator-associated Pneumonia.
The investigators are suggesting that closed suction systems may reduce the risk of the ventilator - associated pneumoniae (VAP) and the contamination of the closest unanimated surfaces. In 2011 David et al.
- Conditions
- Severe Traumatic Brain Injury, Pancreatic Diseases, Trauma Injury, Seizures
- Trial name
- CSS-VAP (NCT04323150)
- Testing
- Closed suction systems, Conventional suction system
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Ventral Hernia
Biological Meshes in Infected Fields: a Randomized Controlled Trial
The SIMBIOSE trial is a large multicenter phase III prospective randomized controlled single blinded trial comparing the use of biological mesh versus traditional wound care without biological mesh in patients with an infected…
- Trial name
- SIMBIOSE (NCT01594450)
- Testing
- Biological mesh, without biological mesh
- Where
- France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Lille
ARDS, Acute Kidney Injury
Mechanical Ventilation-induced Acute Kidney Injury [AKI]
Positive end-expiratory pressure (PEEP) is a fundamental tool in the management of patients with acute respiratory distress syndrome (ARDS). However, there is currently no common criterion for deciding which level of PEEP to use.
- Trial name
- AKI (NCT06638255)
- Testing
- Sequence A involves administering Low PEEP for 12 hours, followed by High PEEP for 12 hours., Sequence B involves setting High PEEP for 12 hours, followed by Low PEEP for 12 hours.
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Total Abdominal Hysterectomy
Are Sutures Required in Total Abdominal Hysterectomy? A Randomised Control Trial
The Hypothesis of this study is that performing total abdominal hysterectomy using the newer electrocoagulation forceps, specifically, the gyrus open seal forceps, curved, compared to the traditional clamp \& suture technique…
- Trial name
- NCT00484835
- Testing
- Performing abdominal hysterectomy using gyrus electrocoagulation forceps
- Where
- 3 sites in Australia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern Health
Wound Surgical, Wound Infection
PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds
Post-operative wound issues in abdominal surgery have a significant impact on patient outcomes. This study is taking place to investigate if Negative Pressure Wound Therapy (NPWT) dressings reduces Surgical Site Infections, post…
- Conditions
- Wound Surgical, Wound Infection, Cosmesis
- Trial name
- PROPEL-2 (NCT05977816)
- Testing
- Negative Pressure Wound Therapy, Standard wound dressing
- Where
- 10 sites in Ireland
- Volunteers
- 2,000 people
- Sponsor
- Royal College of Surgeons, Ireland
Surgical Site Infection, Ventral Hernia
Effect of Active Warming on Surgical Site Infections
This study evaluates the effect of active warming by maintaining the normothermia during abdominal surgical procedures. The investigators hypothesize that there is no difference in terms of preventing surgical site infections…
- Trial name
- NCT04187378
- Testing
- Surgical Underbody Blanket, Surgical access blanket
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul University - Cerrahpasa