Clinical trials: Trauma Blunt
Occult Bleeding, Hemorrhage
A 48 Subject Study Using Non-invasive Multi-Technology Measurements for Early Detection of Ongoing Hemorrhage
Early detection of ongoing hemorrhage (OH) before onset of hemorrhagic shock is a universally acknowledged great unmet need, and particularly important after traumatic injury.
- Conditions
- Occult Bleeding, Hemorrhage, Hemorrhagic Shock
- Trial name
- NCT04814810
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Blunt Abdominal Trauma, Abdominal Injuries
Evaluation of the Blunt Abdominal Trauma Severity Score (BATSS) in Blunt Abdominal Trauma
Blunt abdominal trauma (BAT) is a leading cause of trauma-related morbidity and mortality, commonly caused by motor vehicle collisions, falls, and assaults.
- Conditions
- Blunt Abdominal Trauma, Abdominal Injuries, Intra-Abdominal Injury
- Trial name
- NCT07803211
- Volunteers
- 120 people
- Sponsor
- Assiut University
Thrombosis of Portal Venous System.
Evaluation of Portal Venous System Thrombosis After Blunt Splenic Trauma Utilizing Doppler Ultrasound
The true incidence of thrombosis in the portal venous system after blunt splenic trauma is unknown and has not been elucidated in the medical literature.
- Trial name
- NCT01906983
- Testing
- Doppler Ultrasound
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Blunt Injury of Thorax
STUMBL Score as a Risk Stratification Tool for Management of Blunt Chest Trauma Patients
The aim of this study is to assess validity of the STUMBL score in EGYPT for complications of blunt chest trauma without multi-trauma and immediate life-threatening injuries and identify patients at risk of in- hospital mortality…
- Trial name
- NCT06316375
- Volunteers
- 200 people
- Sponsor
- Assiut University
Head Injury, Traumatic Brain Injury
Selective CT for Anticoagulated Head Injured Patients
The goal is to derive and a clinical decision rule for safe exclusion of traumatic brain injury without neuroimaging in head-injured ED patients who take anticoagulant medications. The objectives are to: 1.
- Conditions
- Head Injury, Traumatic Brain Injury, Intracranial Hemorrhage, Traumatic, Blunt Head Injury
- Trial name
- Can-SCAHn (NCT05364749)
- Where
- 7 sites in Canada
- Volunteers
- 4,000 people
- Sponsor
- Dr. Kerstin de Wit
Sepsis, Septic Shock
Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill Patients
NUROPI is a single-centre, prospective, non-interventional study in the Intensive Care Unit (ICU) of Erasme Hospital (Hôpital Universitaire de Bruxelles, Brussels, Belgium).
- Conditions
- Sepsis, Septic Shock, Cardiac Arrest (CA), Pancreatitis
- Trial name
- NuROPI (NCT07184593)
- Testing
- Plasma H3.1 nucleosome measurement
- Volunteers
- 1,000 people
- Sponsor
- Erasme University Hospital
Abdominal Injuries, Wounds and Injuries
Predictors of In-Hospital Mortality in Severe Abdominal Trauma
Severe abdominal trauma is a leading cause of early death from bleeding and of later death from sepsis and organ failure. Clinicians use scoring systems to estimate the risk of dying, but most of these scores were developed and…
- Conditions
- Abdominal Injuries, Wounds and Injuries, Wounds, Nonpenetrating, Wounds, Penetrating
- Trial name
- NCT07843628
- Where
- Egypt
- Volunteers
- 430 people
- Sponsor
- Minia University
Trauma
Accuracy of the New Injury Severity Score in Evaluating Patients With Blunt Trauma
The goal of this prospective observational study is to evaluate the predictive utility of the New Injury Severity Score (NISS) in determining mortality outcomes among blunt trauma patients admitted to the Emergency Department of…
- Trial name
- NISS/ER (NCT06711276)
- Where
- Iraq
- Volunteers
- 210 people
- Sponsor
- Al-Nahrain University
Acute Blunt Soft Tissue Injuries/Contusions
Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Applied Four Times Daily in Subjects With Acute Blunt Trauma Injuries
The purpose of this study is to evaluate the efficacy of DSG 1% compared with placebo applied four times a day in subjects with acute blunt soft tissue injuries/contusions of the limbs
- Trial name
- NCT01272947
- Testing
- Diclofenac sodium
- Where
- 6 sites in Germany
- Volunteers
- 204 people
- Sponsor
- Novartis
Radiofrequency Can be Used to Treat Splenic Trauma Because of Its Excellent Coagulation Hemostasis
RF-assisted Splenic Preservation VS Conventional Treatment of Blunt Splenic Injury.
Radiofrequency (RF) can be used to treat splenic trauma because of its excellent coagulation hemostasis. This study aimed to compare the efficacy of RF-assisted spleen-preserving surgery with that of conventional…
- Trial name
- NCT03890328
- Testing
- radiofrequency ablation
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Southwest Hospital, China
Bleeding, Aortic Rupture
Life-saving Treatment With Dry-plasma for Massive Bleeding in an Pre-hospital Setting
The overall goal of this clinical trial is to study how prehospital transfused dry plasma affect outcomes in terms of mortality as well as complications and coagulation status of patients in or about to develop bleeding shock.
- Conditions
- Bleeding, Aortic Rupture, Gastrointestinal Hemorrhage, Obstetric Bleeding
- Trial name
- NCT07012863
- Testing
- Dry plasma
- Volunteers
- 650 people
- Sponsor
- Vastra Gotaland Region
Novel STAR Score in Prediction of Intra-Abdominal Injury in Adult Blunt Abdominal Trauma Patients
The Role of Novel STAR Score in Intra-Abdominal Injury in Adult Blunt Abdominal Trauma Patients
This study aim To develop and assess the diagnostic accuracy of the novel STAR score, combining point-of-care abdominal ultrasound and laboratory parameters, for early prediction of intra-abdominal injuries in adult blunt…
- Trial name
- NCT07286617
- Testing
- STAR Score
- Volunteers
- 129 people
- Sponsor
- Assiut University
Rib Fractures, Thoracic Injuries
Ultrasound for Diagnosing Costochondral Joint Separation
This study aims to evaluate the diagnostic effectiveness of ultrasound in detecting costochondral joint separation in patients with blunt thoracic trauma.
- Trial name
- NCT06766721
- Testing
- Ultrasound (USG)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Caner İşevi, MD
Ocular Injury
Study of Retinal Vascular Changes After Ocular Blunt Trauma
This study evaluates the retinal vascular features using optical coherence tomography angiography in patients that received ocular blunt trauma.
- Trial name
- NCT04546997
- Testing
- Optical Coherence Tomography Angiography
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federico II University
Trauma Injury, Trauma Blunt
Extremity Trauma At a Level 1 Trauma Center
Blunt vascular trauma to the lower extremity has been associated with injuries to the anteroposterior tibial arteries or popliteal artery in the form of transection, occlusion, or intimal injury.
- Conditions
- Trauma Injury, Trauma Blunt, Vascular Trauma
- Trial name
- NCT06402669
- Testing
- Packed Red Blood Cell Administration
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Arrowhead Regional Medical Center
Spleen Injury
Observation vs Embolization in Severe Splenic Injury: A Randomized Controlled Trial
Nonoperative management (NOM) of blunt splenic injuries has been the standard of care for decades. While many splenic injuries can be successfully observed, studies have demonstrated increased failure rates for higher grade…
- Trial name
- NCT05008172
- Testing
- Splenic Artery Embolization
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Medical College of Wisconsin
Laparoscopic Surgery
Laparoscopic Splenectomy in Isolated High Grades Splenic Injuries
Background: Trauma laparoscopic splenectomy has no defined reasons. Compared trauma patient characteristics and results with laparoscopic and open splenectomies.
- Trial name
- NCT04329845
- Testing
- open splenectomy, laparoscopic splenectomy for splenic injury in trauma
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Pneumothorax; Acute, Trauma Chest
Occult Pneumothorax in Patients With Blunt or Penetrating Trauma
Pneumothorax is a common life-threatening complication, frequently seen in patients who have been admitted to the emergency department and intensive care unit.
- Trial name
- NCT04188938
- Testing
- Evaluation of occult pneumothorax in who had a blunt or penetrating chest trauma
- Volunteers
- 105 people
- Sponsor
- European University of Lefke
Lung Contusion
AI in the Identification of Lung Contusions Through Chest Radiological Examination in Blunt Thoracic Trauma
The observational study focuses on comparing the interpretation of chest radiological examinations performed using a computer-based system with the standard interpretation conducted by a radiologist.
- Trial name
- NCT06777056
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Rib Fractures
Long-term Outcome After Removal of Rib Stabilization Hardware in Patients With Blunt Chest Trauma
The main study objective is to evaluate the long-term outcome in a prospective follow-up visit of patients who underwent hardware removal after surgical stabilization of rib fractures (SSRF) after a blunt chest trauma .
- Trial name
- REMOVE (NCT06003595)
- Testing
- Data collection on patient reported long-term outcome of SSRF hardware removal
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University Hospital, Basel, Switzerland