Clinical trials: Trauma Injury
Augmented Renal Clearance, Critical Illness
Incidence and Associated Risk Factors of ARC in the Trauma Critically Ill Older Than 50 Years Old
This single-center prospective cohort study conducted at the adult trauma ICU of the Montreal General Hospital (MGH) affiliated with the McGill University Health Centre (MUHC) aims to determine the incidence and associated risk…
- Conditions
- Augmented Renal Clearance, Critical Illness, Polytrauma, Traumatic Brain Injury
- Trial name
- NCT04766944
- Testing
- No intervention
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Elbow Fracture, Trauma
Management of Type 1 Supracondylar Humeral Fractures
This study compares the clinical outcomes of treating pediatric Type 1 supracondylar fracture with a long arm soft cast and no clinical or radiographic follow-up versus the standard treatment in a long arm cast with clinical…
- Trial name
- NCT04642807
- Testing
- Long arm soft cast, Long arm full cast
- Where
- 2 sites in Australia, Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Trauma, Psychological, Depression, Anxiety
Validation of a Dance as Therapy Program in Co-facilitation
The objective is to validate a psychotherapeutic group protocol of dance as therapy created by LOBA association with a comparative non-randomized study.
- Conditions
- Trauma, Psychological, Depression, Anxiety, Stress, Body Image
- Trial name
- VaDDanC (NCT06027658)
- Testing
- RECREATION therapy
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Franche-Comté
Alcohol Use Disorder, Early Trauma Complications
Neurobiological Responses in Alcoholism and Early Trauma
Alcohol use disorder (AUD) accompanied by early trauma presents clinical challenges, including elevated rates of comorbid emotional symptoms and relapse.
- Trial name
- NCT04128228
- Testing
- 8-week outpatient treatment
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Yale University
Sepsis and Septic Shock, Trauma
Fibrinolysis Resistance in Infection and Trauma
Blood coagulation disorders are often seen in critically ill patients e.g. with severe infection or following extensive injury, that can lead to life threatening events as a result of excessive blood clot formation leading to…
- Trial name
- FORTITUDE (NCT06680180)
- Testing
- Viscoelastometric assessment of fibrinolysis
- Where
- 4 sites in Australia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Anders Aneman
Trauma, Psychological, Moral Injury
Wellness Intervention for Nurses Post Traumatic Growth and Selfcare
Nurses working in home and hospice care settings find their roles emotionally challenging and are at high risk for trauma, strain and fatigue. Such sufferings were high among nurses during the Covid-19 pandemic.
- Conditions
- Trauma, Psychological, Moral Injury, Compassion Fatigue
- Trial name
- WINGS (NCT06674876)
- Testing
- Blog writing
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Purdue University
Trauma, Depression
FAmily Oriented Mindfulness Informed Legal Education (FAMiLE) Programme for Parent or Carers Affected by Incarceration and Improving Parenting in Nigeria
Incarceration is a prevalent problem globally and in Nigeria. Its effect significantly impacts left behind parent or primary care givers and also the wellbeing of the families and children.
- Conditions
- Trauma, Depression, Anxiety, Parenting Intervention
- Trial name
- FAMiLE (NCT06628518)
- Testing
- FAmily oriented Mindfulness informed Legal Education (FAMiLE)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Teesside University
Depression, Trauma
Online Therapy Youth, Equivalent to Treatment As Usual?
With growing waiting lists in specialized youth mental health care (sGGZ) and shortages of care staff, finding creative solutions to respond to this scarcity issue is important.
- Conditions
- Depression, Trauma, Compulsive Disorder, Anxiety
- Trial name
- NCT06617663
- Testing
- EMDR, ACT
- Where
- Netherlands
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- GGZ Noord-Holland-Noord
Trauma, Childbirth Problems
Study of the Identification of Childbirth Trauma in the Birth Room by Midwives.
Childbirth is a critical moment in this perinatal period, with high unpredictability and risks of medical complications for the mother and child. It can be experienced as a traumatic experience for the woman.
- Trial name
- TOPASE (NCT06204757)
- Testing
- questionary
- Where
- France
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Child Safety, Coercion
Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families
This Randomized Controlled Trial will test the effectiveness of the Parenting in the Moment (PIM) online parenting program for parents with experiences of forced displacement.
- Conditions
- Child Safety, Coercion, Child Wellbeing, Adjustment
- Trial name
- PIMonline (NCT06548126)
- Testing
- Online Parenting Program, No online parenting program
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Depression, Anxiety, Trauma
Problem Management Plus Mindfulness-informed Legal Education for Addressing Gender-based Violence and Improving Parenting
Gender-based violence and, more specifically, domestic violence is a prevalent problem globally and in Nigeria. Its effect significantly impacts women and also the wellbeing of their families.
- Conditions
- Depression, Anxiety, Trauma, Anxiety, Parenting Intervention
- Trial name
- PM+MiLE (NCT06601023)
- Testing
- Psychosocial intervention
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Teesside University
Trauma, Anxiety
The Ukrainian Student Problem Solving Project
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06064578
- Testing
- Project SOLVE
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Harvard University
Trauma, Anxiety
Testing the Effects of Project Calm in Ukrainian Schools
The purpose of this study is to test the effectiveness of a universal, digital, single-session intervention for youth mental health, functioning, and well-being, when implemented with Ukrainian children and adolescents.
- Conditions
- Trauma, Anxiety, Depression, Child Behavior
- Trial name
- NCT06217705
- Testing
- Project Calm
- Where
- United States
- Volunteers
- 728 people, healthy volunteers welcome
- Sponsor
- Harvard University
Multi-organ Failure After Severe Trauma
Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma
Severe trauma remains the leading cause of death in people under 50, and is associated with high morbidity, including severe disability, with a substantial socio-economic impact.
- Trial name
- METAKIT (NCT06167512)
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Trauma, Psychological, Prenatal Stress
Supporting the Transition to and Engagement in Parenthood
STEP (Supporting the Transition to and Engagement in Parenthood) is a manualized group intervention for pregnant women exposed to early life adversity designed to foster emotion regulation and reflective capacities in…
- Conditions
- Trauma, Psychological, Prenatal Stress, Mental Health Issue, Maternal Distress
- Trial name
- STEP (NCT04829864)
- Testing
- STEP
- Where
- 2 sites in Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Apical Periodontitis, Trauma
Revitalization of Traumatized Immature Permanent Teeth
This study aims to assess the hypothesis that revitalization of teeth without (a)symptomatic apical periodontitis have a more favourable outcome in terms of further root development, periapical bone healing, maintaining/regaining…
- Trial name
- NCT06043453
- Testing
- revitalization
- Where
- Belgium
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Overuse Injury
Throwing Device Tracker for Youth Injury Prevention
The primary objective of this study is to collect motion-capture data on movements common to baseball play in order to develop an algorithm for a wearable device for the prevention and rehabilitation of sports-related overuse…
- Trial name
- NCT04098107
- Testing
- Throwing Device
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Traumatic Brain Injury, Multiple Trauma
Evolution of Oropharyngeal and Rectal Microbiota After Severe Traumatic Brain Injury
Modifications of the human gut microbiota have been associated with different pathological conditions such as obesity, inflammatory bowel diseases and neurodegenerative diseases.
- Trial name
- BBAX (NCT03965611)
- Testing
- Oropharyngeal swab, Rectal swab, Disability rating scale (DRS-F)
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mild Cognitive Impairment, Older Adults
Effectiveness of Alternative Therapy for Improving Cognition, Balance, and Physical Activity
The composite effect of reduced balance, cognition, gait abnormalities/gait disturbances, and physical activity in older adults with mild cognitive impairments (MCI) leads to fear of falling and reduced participation in daily…
- Conditions
- Mild Cognitive Impairment, Older Adults, Neurological Injury
- Trial name
- NCT04160299
- Testing
- Dance-based exergaming
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Neurological Injury, Motor Disorders
Transcutaneous Auricular Vagus Nerve Stimulation to Enhance Motor Learning
Vagus nerve stimulation (VNS) activates neural pathways leading to the release of chemicals that promote plasticity and learning.
- Conditions
- Neurological Injury, Motor Disorders, Paresis
- Trial name
- NCT05316519
- Testing
- Transcutaneous Vagus Nerve Stimulation
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- VA Pittsburgh Healthcare System