Clinical trials: Trauma Nervous System
Hearing Loss, Sensorineural, Hearing Loss, Conductive
Wide Frequency Band Test of Hearing in Veterans
The accurate assessment of auditory status is critical for planning treatment for Veterans with hearing loss to include medical and audiological management.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Otosclerosis
- Trial name
- CWTBAFV (NCT02019888)
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Phantom Limb
Virtual Integrated Environment in Decreasing Phantom Limb Pain
The purpose of this study is to determine if observing a virtual arm decreases phantom limb pain (PLP) in upper extremity amputees.
- Trial name
- VIE (NCT01462461)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Cold Hypersensitivity, Vascular System Injuries
Treatment of Frostbite Sequelae With Botulinum Toxin A
Background Digital vasospasm as part of frostbite sequelae is comparable to the vasospastic disorders found in Raynaud's phenomenon which has been successfully treated with Botulinum toxin type A injections in the palm of the…
- Conditions
- Cold Hypersensitivity, Vascular System Injuries, Vibration; Disorder, Sensory Disorders
- Trial name
- NCT06460194
- Testing
- Botuinum toxin
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Alzheimer's Disease (AD), Parkinson's Disease (PD)
Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects
The goal of this study is to assess [18F]MNI-777 PET imaging as a tool to detect tau pathology in the brain of individuals who carry a clinical diagnosis of a tauopathy, including: Alzheimer's Disease (AD),Parkinson's disease…
- Conditions
- Alzheimer's Disease (AD), Parkinson's Disease (PD), Chronic Traumatic Encephalopathy (CTE), Progressive Supranuclear Palsy (PSP)
- Trial name
- NCT02103894
- Testing
- [18F]T807 ([18F]MNI-777)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Molecular NeuroImaging
Spinal Cord Injury
Mechanisms of Orthostatic Intolerance in Spinal Cord Injured Individuals and Following Bed Rest
The primary purpose of this study is to investigate the relationship between the extent of neurologic (nerve) impairment in patients with spinal cord injuries and how well the nerves passing down the spine to the heart and blood…
- Trial name
- NCT00175773
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Trauma, Brain
Risk Assessment of Mild Traumatic Brain Injury in Military Training
The SNIPER-TBI study aims to identify and quantify the risk of mild traumatic brain injury (mTBI) in soldiers of the Czech Armed Forces during specific high-risk training activities, including parachute jumps, high-caliber…
- Trial name
- NCT06992570
- Testing
- Quantification of mild trauma brain injury risk, Biomechanical Analysis of Head Impact Forces
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Cochlear Hearing Loss, Hearing Loss, Sensorineural
Minimizing Facial Nerve Stimulation in Cochlear Implants
This study aims to understand how to manipulate the electrical stimulation from the cochlear implant to maximize hearing stimulation and minimize facial stimulation.
- Conditions
- Cochlear Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Facial Nerve Injury
- Trial name
- NCT04161261
- Testing
- Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Stroke, Able Bodied
Stimulation-Based Modulation of Spinal and Cortical Sensory Pathways
The goal of this study is to assess cervical (neck) reflexes by intra-operatively stimulating the neck nerve roots to evoke motor responses through their connections to spinal motoneurons.
- Trial name
- NCT07401186
- Testing
- Bipolar Neural Stimulation Electrode
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Peter C. Gerszten, MD
Postoperative Pain
TAP Block With Liposomal Bupivacaine Versus Pre-incisional Wound Infiltration With Bupivacaine for Postoperative Pain
In this randomized, controlled, double-blinded trial we plan to evaluate post-operative pain relief after laparoscopic-assisted Transversus Abdominis Plane (TAP) block using liposomal bupivacaine plus bupivacaine versus…
- Trial name
- LATAP (NCT02400645)
- Testing
- Pre-incisional wound infiltration, Laparoscope to place TAP block with liposomal bupivacaine, Liposomal bupivacaine
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Dry Needling, Carpal Tunnel Syndrome
Dry Needling and Rehabilitatin Carpal Tunnel Syndrome
Dry needling is used for myofascial release. However, its effectiveness in carpal tunnel syndrome (CTS) is not well known. It is thought that dry needling may also be an effective treatment for CTS by providing relaxation in the…
- Conditions
- Dry Needling, Carpal Tunnel Syndrome, Myofacial Pain
- Trial name
- NCT06358326
- Testing
- Dry needling, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Karabuk University
MTBI - Mild Traumatic Brain Injury
Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders
The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.
- Trial name
- NCT07282691
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Salus University
Concussion Injury of Cerebrum, Cranial Osteopathic Medicine
Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion
Patients who have concussions exhibit an array of symptoms, also known as post-concussive symptoms, including headaches, feeling slowed down or foggy and difficulty with concentration.
- Trial name
- NCT03225599
- Testing
- Cranial Osteopathic Manipulative Medicine
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Traumatic Brain Injury
Translational Research Examining Acupuncture Treatment in Traumatic Brain Injury
The purpose of this study is to examine the effects of acupuncture on cerebral blood flow (CBF) and blood biomarkers during the acute 10-day window following traumatic brain injury, to determine if those changes correlate with…
- Trial name
- TREAT-TBI (NCT02623218)
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- AOMA Graduate School of Integrative Medicine
Concussion, Brain
Neck Strengthening Program for the Prevention or Mitigation of Sports Concussion
Study looks to determine effectiveness of neck strengthening to reduce the incident, duration, and severity of sports related concussion in student athletes.
- Trial name
- PCONS (NCT03237468)
- Testing
- Neck strengthening exercise to prevent concussion
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- CentraCare
Ambulances, Traumatic Brain Injury
Differences in Mortality and Morbidity in Patients Suffering a Time-critical Condition Between GEMS and HEMS
Introduction: Patients suffering a time-critical medical condition require rapid prehospital assessment and treatment and most often quick transportation to definitive care. This can be decisive for patient outcome.
- Conditions
- Ambulances, Traumatic Brain Injury, Acute Myocardial Infarction
- Trial name
- NCT03940443
- Where
- Sweden
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Mild Traumatic Brain Injury
Deployment Related Mild Traumatic Brain Injury (mTBI)
The study will provide evidence on the long term outcomes of mTBI in service members returning from Afghanistan and Iraq. In addition, the study will provide evidence on mTBI incidence, and symptom patterns.
- Trial name
- NCT01847040
- Where
- 2 sites in United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- The Defense and Veterans Brain Injury Center
Thoracic Diseases, Thoracic Surgery
Deep Serratus Anterior Plane Block vs Surgically-placed Paravertebral Block for VATS Surgery
Thoracic surgery, and surgery involving the chest wall in general, is associated with poorly controlled acute pain, which may result in delayed functional recovery, and may progress to chronic pain.
- Conditions
- Thoracic Diseases, Thoracic Surgery, Rib Fractures, Pain, Postoperative
- Trial name
- SAPB (NCT03768193)
- Testing
- Deep serratus anterior plane block, Surgically-placed paravertebral block
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mater Misericordiae University Hospital
Acute Pain, Sports Injury
Integrative Ayurveda Healing Relieves Minor Sports Injury Pain
Sports-related soft tissue injuries, such as sprains, strains, and contusions, are a common painful condition. Current treatment includes oral nonsteroidal anti-inflammatory drugs (NSAIDs), which have a high incidence of…
- Trial name
- NCT02380989
- Testing
- Ayurveda
- Where
- 3 sites in India
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Adwin Life Care
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
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