Clinical trials: Trauma Patients
Prevention, Rehabilitation
Dysphagia and Cervical Spine Disorders in Patients With Brain Lesions
The research is about a prospective study conducted in patients suffering from dysphagia and cervical spine disorders and how they are interrelated.
- Trial name
- DysphagCerv (NCT01418105)
- Testing
- Videofluroscopic swallow study (VFSS), cervical spine isometric exercises, Fiberoptic endoscopic esophageal study (FEES)
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Ioannina
Walking
Frontal Lobe Oxyhemoglobin Levels in Patients With Lower Extremity Burns Assessed Using a fNIRS
Investigators investigate the patterns of cortical activation using the NIRST in patients with peripheral neurological injury caused by lower extremity burns.
- Trial name
- fNIRS (NCT03990831)
- Testing
- Functional near-infrared spectroscopy (fNIRS)
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hangang Sacred Heart Hospital
Intubation; Difficult or Failed, Airway Complication of Anesthesia
Comparing Full vs. Partial Glottis View Using CMAC D-Blade Video Laryngoscope in Simulated Cervical Injury Patient
Direct laryngoscope requires proper alignment of the oro-pharyngeal-laryngeal axis to provide an optimal glottic view for intubation.
- Trial name
- NCT04833166
- Testing
- CMAC D-blade videolaryngoscope with full or partial glottic view
- Where
- Malaysia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Laser Ablation
The primary objectives of this study are to evaluate safety and efficacy of topically applied Glucoprime gel (GLYC-101, 0.1% and GLYC-101, 1.0%) in promoting wound healing in cosmetic surgery patients undergoing Carbon Dioxide…
- Trial name
- NCT00792688
- Testing
- GLYC-101 Gel (0.1%), GLYC-101 Gel (1.0%)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Reduction of Empathy-Based Stress in Healthcare Staff
Compassion Project: Developing an Empathy-Based Stress Intervention
Compassion is recognising that someone is suffering and wanting to help them. Compassion fatigue is a reduction in capacity to feel compassion for others.
- Trial name
- NCT06343818
- Testing
- The Compassion Project: Intervention to Reduce Empathy-Based Stress in Staff
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bath
Trauma Injury, Haemorrhagic Shock
Prediction of Massive Transfusion in Trauma Patients
Since the 2000s, many prognostic scores were developed to predict traumatic haemorrhage. Most of these studies were retrospectives based on registers.
- Conditions
- Trauma Injury, Haemorrhagic Shock, Bleeding, Emergencies
- Trial name
- MTP (NCT04561050)
- Testing
- Comparison of score performances (Overall performance, discrimination and calibration)
- Where
- Switzerland
- Volunteers
- 13,222 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
REM Sleep Behavior Disorder, Concussion, Brain
The COSP-RBD Study: Concussions and Contact Sports in RBD vs Controls
The goal of this observational study is to investigate concussions and contact sports practices in REM sleep behaviour disorder (RBD).
- Trial name
- COSP-RBD (NCT06270290)
- Testing
- Exposure to contact sports or history of concussions
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Shock,Hemorrhagic
A Study to Evaluate the Safety and Tolerability of Valproic Acid in Healthy Volunteers (Part 1)
The purpose of the first part of this study is to determine the safety and tolerability of ascending doses of valproic acid (also known as Depacon) administered as intravenous infusion (IV) in doses ranging from 15 mg/kg to 250…
- Trial name
- NCT01951560
- Testing
- Valproic Acid, Isotonic saline solution
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dr. Hasan Alam
Myocardial Injury
Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Myocardial Injury in Elderly Patients Undergoing Thoracoscopic Surgery: a Prospective, Randomized Controlled Study
This research group plans to design a prospective, double-blind, randomized controlled study to explore the effect of taVNS on hs-cTnT in elderly patients undergoing thoracoscopic surgery, and to evaluate the effect on…
- Trial name
- NCT06759818
- Testing
- transcutaneous vagus nerve stimulation
- Where
- China
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
Osteoarthritis
Developing Allogeneic Musculoskeletal Therapies
The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other…
- Trial name
- NCT06167928
- Where
- United Kingdom
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Keele University
Acute Spinal Cord Injury
Spinal Cord Injury Neuroprotection With Glyburide
To assess the safety and efficacy of using oral Glyburide (Diabeta) as a neuroprotective agent in patients with acute cervical or thoracic traumatic spinal cord injury.
- Trial name
- SCING (NCT05426681)
- Testing
- GlyBURIDE Oral Tablet
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Francis Farhadi
Mandibular Fractures
Specific Screw Holes Locating Surgical Guide and Pre-bent Plates
The aim of the current study was to evaluate the accuracy of computer-guided mandibular fracture reduction versus the classical work flow
- Trial name
- NCT05444829
- Testing
- specific screw holes locating surgical guide and pre-bent plates, classical reduction and internal fixation.
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Abdallah Gaber Ali Mohamed
Zygomatic Fractures
A Full Digital VS Conventional Protocol in Management of Zygomatico-Maxillary Complex Fracture
this study aims To evaluate The Accuracy of Zygomatico- Maxillary Complex (ZMC) Fracture reduction and fixation Using customized Patient-Specific implant and patient-specific predictive holes surgical guide Versus Conventional…
- Trial name
- NCT06588075
- Testing
- Reduction and fixation of zygomatico- Maxillary complex fracture using a full digital work flow, Reduction and fixation of zygomatico- maxillary complex fracture using a conventional free hand protocol
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Subacromial Impingement Syndrome
Investigation of the Effectiveness of Core Stabilization Training in Patients With Subacromial Impingement Syndrome
Subacromial Impingement Syndrome (SIS) is one of the most common shoulder problems. The core region is considered a kinetic link that facilitates the transfer of torque and angular momentum between the upper and lower extremities…
- Trial name
- NCT05966298
- Testing
- Core stabilization training, Standart Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Distal Radius Fracture
Early Mobilization Following Volar Locking Plate Fixation of Distal Radius Fractures
The overall purpose of this study is to establish the utility of early mobilization in improving patient satisfaction following plate and screw fixation of wrist fractures.
- Trial name
- NCT05033938
- Testing
- Early Mobilization Protocol, Late Mobilization Protocol
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Robert Wood Johnson Barnabas Health
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction Rehabilitation
Eccentric Phase Biomechanics of the Countermovement Jump After Anterior Cruciate Ligament Reconstruction
Purpose: This study aims to better understand how force is produced during a vertical jump in individuals approximately six months after anterior cruciate ligament reconstruction compared with healthy individuals.
- Trial name
- DECAL (NCT07448064)
- Testing
- Countermovement Jump Force Platform Assessment, Isokinetic Test
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haute Ecole ARC Sante
Meniscus Injury, Meniscectomy
Biomechanical Osteoarthritis Outcomes in Meniscectomy Patients
The key aim of this study is to examine biomechanical measures associated with osteoarthritis (OA) progression in patients who have lateral and medial menisci injuries during various tasks.
- Conditions
- Meniscus Injury, Meniscectomy, Osteoarthritis, Knee
- Trial name
- BOOM (NCT03350204)
- Testing
- Meniscectomy, Helathy control comparison
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Salford
Injury Traumatic, Injuries
Trauma Follow-Up Prediction (Project 2: Aim 2)
Approximately 9% of the world's deaths, more than 5 million deaths annually, are due to injury. In high-income countries, where the epidemiology and outcomes of traumatic injury are well characterized, trauma primarily affects…
- Trial name
- NCT05464017
- Testing
- Optimized version of the mHealth screening tool (intervention) using the machine learning approach
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- University of Buea
MSCs
MSCs Source of Sweat Gland Cells of Large Area Skin Injury Patients Transplant of the Wound
The main purpose of this test is to assess the umbilical cord mesenchymal stem cells (MSCs) UC between source sample sweat gland cells wound transplanted effectiveness and safety for the treatment of large area skin lesions of…
- Trial name
- MSCs (NCT02669199)
- Testing
- MSCs
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Bariatric Surgery, Osteoporosis
Skeletal Health in Bariatric Surgery Patients
The investigators propose a prospective cohort trial that will help to understand the impact of Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in pre- and post-menopausal female bariatric patients.
- Conditions
- Bariatric Surgery, Osteoporosis, Fractures, Bone, Roux En-Y Gastric Bypass
- Trial name
- NCT03331536
- Testing
- Roux en Y Gastric Bypass Pre-menopausal, Roux en Y Gastric Bypass Post-menopausal, Sleeve Gastrectomy Pre-menopausal
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham