Clinical trials: Trauma Patients
PTSD, Trauma
PPG Project 3 - PET/MRI of the Brain-hematopoiesis-atherosclerosis Axis in PTSD Patients
Project 3 of the PPG grant "Stress and Atherosclerotic Plaque Macrophages A Systems Biology Approach," funded by the NHLBI, examines the relationship between psychosocial stress and atherosclerotic inflammation, cell…
- Conditions
- PTSD, Trauma, Healthy
- Trial name
- NCT03279393
- Testing
- fluorodeoxyglucose (FDG)-PET/MRI
- Where
- 2 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Zahi Fayad
Chronic Wound
A Prospective Clinical Study Evaluating the Harvesting of Micografts
ART (Autologous Regeneration of Tissue) is a revolutionary technology for harvesting skin without the drawbacks of conventional grafting.
- Trial name
- NCT05076578
- Testing
- Autologous Regeneration of Tissue (ARTTM) system
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SerenaGroup, Inc.
Grief, Trauma
A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients
Hypotheses 1a and 1b: Compared to Supportive Conversation arm, the EMPOWER intervention will significantly decrease surrogate decision makers' symptoms of grief and Post Traumatic Stress Disorder (PTSD) (primary outcomes); and…
- Conditions
- Grief, Trauma, Psychotherapy, Critical Care
- Trial name
- NCT05587517
- Testing
- EMPOWER, Supportive Conversation
- Where
- 3 sites in United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Vertebral Fracture
Prevalence of Subclinical Vertebral Fractures in Rheumatoid Arthritis and Ankylosing Spondylitis
Study of prevalence of subclinical vertebral fractures in Rheumatoid Arthritis and Ankylosing spondylitis
- Trial name
- NCT06092775
- Testing
- DEXA scan,X_ray
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Assiut University
Rupture of Anterior Cruciate Ligament
A Pilot Study to Investigate Biomarkers in Anterior Cruciate Ligament (ACL) Patients and Healthy Controls
Incident rates of ACL rupture are greatest in 16-39 year olds at almost 1 in 1,000. Performance Based Investigations (PBIs) can be used to evaluate and select correct approaches to patient treatment, and biochemical…
- Trial name
- NCT02300012
- Testing
- Surgeons knowledge of pre-operative PBIs
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- United Lincolnshire Hospitals NHS Trust
Stroke, Parkinson Disease
Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk
The purpose of this study is to evaluate the feasibility and efficacy of a smart airbag system that detects and mitigates fall-related impact in individuals with high fall risk.
- Conditions
- Stroke, Parkinson Disease, Lower Limb Amputation Knee, Fall Injury
- Trial name
- NCT05076565
- Testing
- Airbag Belt Fall Protection System
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
ACL - Anterior Cruciate Ligament Rupture
Prospective Evaluation of Osseous Integration in ACL Reconstruction Comparing Tightrope vs Interference Screw Fixation
The purpose of our study was to compare osseous integration of the bone block in Achilles tendon allograft ACL reconstruction using a cortical button versus biocomposite interference screw fixation.
- Trial name
- NCT03841500
- Testing
- Biocomposite intereference screw femoral tunnel fixation, Endobutton (Tightrope) femoral tunnel fixation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Kelsey-Seybold Clinic
Covid19, SARS-CoV2 Infection
Coronaltitude - Multicentric Evaluation of the Impact on Hypoxia Sensitivity of Patients With COVID-19
In this study, the investigators will examine the extent to which having suffered coronavirus disease 2019 (COVID19) impacts one's sensibility to hypoxia by means of the 'Richalet test'.
- Conditions
- Covid19, SARS-CoV2 Infection, Hypoxia, Altitude
- Trial name
- NCT05167357
- Testing
- COVID19
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Institut de Formation et de Recherche en Médecine de Montagne
Carpal Tunnel Syndrome, Psoriatic Arthritis
Carpal Tunnel Syndrome in Patients With Psoriatic Arthritis
This study aimed to investigate median nerve hypervasculatitation in psoriatic arthritis (PsA) patients with CTS or without CTS by using SMI, then compare them with normal people.
- Trial name
- NCT05086029
- Testing
- Superb Microvascular Imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Brachial Plexus Injury
Changes in Optic Nerve Sheath Diameter in Response to Various Levels of End Tidal Carbon Dioxide Levels
Intracranial Pressure ( ICP ) monitoring is an essential component of traumatic brain injured ( TBI ) patients management. The clinical signs of raised ICP may be unreliable and may reflect relatively late cerebral…
- Trial name
- NCT02711774
- Testing
- ultrasonography
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Ankle Fractures, Pain, Postoperative
Ropivacaine Versus Bupivacaine as Preemptive Analgesia in Surgical Site in Ankle Fracture Patients
Title: Ropivacaine versus Bupivacaine as Preventive Analgesia in Surgical Incision Site In Patients With Ankle Fracture Background: Ankle fractures are about 10% of the fractures associate to sports and with an incidence of 0.11…
- Conditions
- Ankle Fractures, Pain, Postoperative, Local Infiltration
- Trial name
- NCT02949674
- Testing
- Ropivacaine, Bupivacaine
- Where
- Mexico
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Traumatic Pneumothorax
Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax
A small 14-French(F) pigtail catheter (PC) has been shown to work equally well with traditional 32-40F chest tube (CT), especially in traumatic pneumothorax. There are no clinical data on tube-site pain.
- Trial name
- NCT01537289
- Testing
- Pigtail catheter insertion (Cook), chest tube (28-French)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Surgical Site Infection
PICO Dressings for Emergency Laparotomy
SSI (Surgical Site Infection) rate is an important consideration after emergency laparotomy. SSIs carry a high financial burden for health institutes with the cost of major SSIs after emergency laparotomy to add an additional…
- Trial name
- NCT05090462
- Testing
- PICO dressing
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- North Middlesex University Hospital NHS Trust
Gastroparesis, Hip Fracture
Gastric Emptying in Elderly With Hip Fracture
The gastric emptying of 400 ml 12.6% carbohydrate rich drink is investigated in elderly women, age 75-100, with acute hip fracture.
- Conditions
- Gastroparesis, Hip Fracture, Mild Insufficient Nutrition
- Trial name
- GASEMPHIP (NCT02753010)
- Testing
- Gastric emptying of carbohydrate-rich beverage
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Delirium
Dexmedetomidine Versus Propofol for Prolonged Sedation in Critically Ill Trauma and Surgical Patients
The purpose of this study is to assess the efficacy of dexmedetomidine versus propofol for prolonged sedation in trauma and surgical patients.
- Trial name
- NCT02548923
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Tennessee Graduate School of Medicine
Fractured Neck of Femur
Single Dose of Dexamethasone in Femur Fractures
Fracture neck of femur is a common cause of hospital admission in the elderly and requires operative fixation. Dexamethasone has the potential of inhibiting cortisol secretion.
- Trial name
- NCT01550146
- Testing
- Dexamethasone acetate
- Where
- Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
FMD, IMT
Arterial Remodeling in Smokers
Cigarette smoking is the most important modifiable cardiovascular risk factor leading to endothelial dysfunction and was suggested to impair arterial regeneration.The aim of the study was to investigate the effect of smoking on…
- Conditions
- FMD, IMT, Smoking
- Trial name
- TCA (NCT01862146)
- Testing
- smoke expose
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Groin Pain
Anatomical, Radiological and Biomechanical Examination of Athletic Groin Pain Patients and Physical Therapy Intervention
Athletic groin pain (AGP) is a chronic condition common in multi-directional sports (Walden et al. 2007, Robinson et al. 2004, Murphy et al. 2012). It is a complex injury with a challenging diagnosis.
- Trial name
- NCT02437942
- Testing
- Biomechanics led physical therapy rehabilitation
- Where
- Ireland
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Sports Surgery Clinic, Santry, Dublin
Transplant;Failure,Kidney
Utility of a Novel Dd-cfDNA Test to Detect Injury in Renal Post-Transplant Patients
Detecting allograft injury and rejection is critical to preventing graft loss. The current standard of care (SoC) relies on serum creatinine (SC) and biopsy to monitor for and identify kidney injury earlier.
- Trial name
- QIDNEY (NCT03765203)
- Testing
- Natera KidneyScan, Clinical Performance and Value Vignettes
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Firearm Injury, Violence, Physical
HVIP Outcomes and Stakeholder Insights
The study's goal is to perform an evaluation of a Southeastern hospital violence intervention program (HVIP) that includes comprehensive patient outcomes, perceived benefits and opportunities for improvement of an HVIP from the…
- Trial name
- NCT06582953
- Testing
- Turning the Tide Violence Intervention Program (hospital violence intervention program)
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina