Clinical trials: Trauma Patients, active
AKI (Acute Kidney Injury) Due to Trauma
Acute Kidney Injury and Ultra-endurance Running
This study aims to understand how participating in the Western States Endurance Run (WSER), a 100-mile ultramarathon, affects kidney health.
- Trial name
- NCT07519408
- Testing
- Sodium Bicarbonate (NaHCO3)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cerebrovascular Trauma
Universal Screening for Blunt Cerebrovascular Injury
The goal of this clinical trial is to test whether screening all major blunt trauma patients for blood vessel injuries in the neck and head using CT scans (universal screening) leads to fewer strokes and stroke-related deaths…
- Trial name
- PRaCTUS BCVI (NCT07919847)
- Testing
- Selective Screening, Universal Screening
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Inova Health Care Services
Trauma Centers/Statistics & Numerical Data, Trauma Blunt
Medical,Nursing Record,PE, Blood Test and Radiological Examination ,Morality and Mobility of Multiple Trauma Patient
This study aims to analyze statistical data on physiological examination values, blood test results, and radiological findings in patients admitted to the emergency department for severe trauma.
- Conditions
- Trauma Centers/Statistics & Numerical Data, Trauma Blunt, Trauma (Including Fractures), Trauma Abdomen
- Trial name
- trauma (NCT07903727)
- Testing
- Collect results of trauma patients
- Volunteers
- 700 people
- Sponsor
- St. Martin De Porress Hospital
Trauma, Psychological, Traumatic Stress Disorder
Magnetoencephalographic Correlates of Clinical Change After Cognitive Processing Therapy in Adults With PTSD
Cognitive Processing Therapy (CPT) is a first-line, evidence-based trauma-focused treatment for posttraumatic stress disorder (PTSD), but the clinical and neurophysiological mechanisms underlying therapeutic response remain…
- Trial name
- REC-HEALING-TR (NCT07917377)
- Testing
- Behavioral: Cognitive Processing Therapy (individual), Magnetoencephalography (MEG)
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Insomnia, Nightmares Associated With Trauma and Stress
Restorative Early Sleep Treatment After the Emergency Department
The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep…
- Conditions
- Insomnia, Nightmares Associated With Trauma and Stress, Nightmares, PTSD - Post Traumatic Stress Disorder
- Trial name
- RESTED (NCT07121270)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Cognitive Behavioral Therapy for Insomnia and Nightmares, Sleep Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Henry Ford Health System
Stroke, Spinal Cord Injuries (SCI)
Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)
Rehabilitation remains important in the chronic phase after stroke or spinal cord injury, as meaningful improvements may still be achieved through intensive, goal-directed, and personalized training.
- Conditions
- Stroke, Spinal Cord Injuries (SCI), Chronic Disease
- Trial name
- INTeRAcT-bis (NCT07912320)
- Testing
- Intensive rehabilitation programme
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Depression, Trauma, Psychological
Early Life Stress and Depression: Molecular and Functional Imaging
Severe childhood adversity accounts for a large portion of psychiatric illness, and an increased risk for major depressive disorder (MDD).
- Trial name
- ELS (NCT04713722)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Pregnant Women, Prenatal Yoga
Prenatal Yoga Intervention in Pregnant Women
The aim of this study is to determine the effects of a prenatal yoga intervention on traumatic childbirth perception, self-perception, and delivery preferences in pregnant women.
- Conditions
- Pregnant Women, Prenatal Yoga, Trauma, Body Image
- Trial name
- NCT07585916
- Testing
- Prenatal Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Trauma, Young Adult Females
Trauma-Informed Yoga Intervention in Young Women
The aim of this study is to evaluate the effects of a trauma-informed yoga intervention on psychological trauma symptoms, difficulties in emotion regulation, and interoceptive awareness in young adult women.
- Conditions
- Trauma, Young Adult Females, Awareness, Emotional Regulation
- Trial name
- NCT07589777
- Testing
- Trauma-Informed Yoga Intervention Program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Trauma, Hemorrhage
CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial
The CAlcium and VAsopressin following Injury Early Resuscitation (CAVALIER) Trial is a proposed 4 year, double-blind, mutli-center, prehospital and early in hospital phase randomized trial designed to determine the efficacy and…
- Trial name
- CAVALIER (NCT05958342)
- Testing
- Calcium Gluconate, Vasopressin
- Where
- 18 sites in United States
- Volunteers
- 1,050 people
- Sponsor
- Jason Sperry
Trauma, Brain
Risk Assessment of Mild Traumatic Brain Injury in Military Training
The SNIPER-TBI study aims to identify and quantify the risk of mild traumatic brain injury (mTBI) in soldiers of the Czech Armed Forces during specific high-risk training activities, including parachute jumps, high-caliber…
- Trial name
- NCT06992570
- Testing
- Quantification of mild trauma brain injury risk, Biomechanical Analysis of Head Impact Forces
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Post-traumatic Stress Disorder
Recovering Sleep After Trauma
The main objective of this pilot trial is to assess the feasibility and preliminary efficacy of telehealth-delivered behavioral therapy to reduce the development of posttraumatic stress and depressive symptoms following motor…
- Trial name
- REST (NCT07196332)
- Testing
- Brief Behavioral Treatment for Insomnia (BBTI), Progressive Muscle Relaxation Training (PMRT)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of North Carolina, Chapel Hill
Thigh Muscle Injury, Thigh Injury
PPP Versus Corticosteroid for Thigh Muscle Injuries
The purpose of this study is to compare the number of days it takes for a sport participant to return to play between ultrasound guided intramuscular corticosteroid injections and platelet-poor plasma (PPP) injections for thigh…
- Conditions
- Thigh Muscle Injury, Thigh Injury, Musculoskeletal, Musculoskeletal Injury Trauma
- Trial name
- NCT07513142
- Testing
- Corticosteroid, Platelet Poor Plasma
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Andrews Research & Education Foundation
Opioid Use, Fractures, Bone
Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures
An open reduction and internal fixation is a painful procedure requiring intensive postoperative pain management. Traditionally, opioid analgesia has been the gold standard for postoperative pain control.
- Conditions
- Opioid Use, Fractures, Bone, Trauma
- Trial name
- NCT06113211
- Testing
- Narcotic pain medication, Nonnarcotic pain medications
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Henry Ford Health System
Multiple Trauma/Injuries
Collecting the Results of Multiple Trauma Patients and Find the Correlation of Morality and Mobility
Collect data about physiological examination values, blood test values and radiological examination results of patients admitted to the hospital for major trauma.
- Trial name
- trauma (NCT06216873)
- Testing
- multiple trauma
- Where
- 2 sites in Taiwan
- Volunteers
- 400 people
- Sponsor
- St. Martin De Porress Hospital
Trauma, Appendectomy
Hospital Based Continuous Patient Monitoring System
In Ghana, and many other low and middle income countries in Africa, manual vital signs monitoring is the prevalent mode of vital signs monitoring because continuous bedside monitors are non-functional.
- Conditions
- Trauma, Appendectomy, Pediatric ALL, Vital Signs Monitoring
- Trial name
- NCT06739447
- Testing
- Consumer Wearable Device Vital Sign Measurement
- Where
- Ghana
- Volunteers
- 250 people
- Sponsor
- University of Alabama at Birmingham
Burnout, Secondary Trauma
PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial)
The investigators propose to test the effectiveness of PATH (Peer Advanced Training for total Health) as an educational workforce intervention for improving peer recovery support specialists' (PRSS) overdose prevention (OP)…
- Conditions
- Burnout, Secondary Trauma, Compassion Fatigue, Opioid Use Disorder
- Trial name
- NCT07886944
- Testing
- PATH (Peer Advanced Training for total Health)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Chestnut Health Systems
Trauma, Psychological, Traumatic Stress Disorder
Group Cognitive Processing Therapy for Women Survivors of Gender-Based Violence: Feasibility Study
Introduction: Post-traumatic stress disorder (PTSD) is a global health challenge requiring effective, evidence-based interventions, such as Cognitive Processing Therapy (CPT).
- Trial name
- HEALING-TRAUMA (NCT07897903)
- Testing
- Group CPT + TAU (Experimental)
- Volunteers
- 10 people
- Sponsor
- Universidad Complutense de Madrid
Urologic Diseases, Male Urogenital Diseases
Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile Corpora
The primary objective of this clinical trial is to evaluate the safety of autologous engineered corpora cavernosa + albuginea constructs for treatment of complex penile deformities.
- Conditions
- Urologic Diseases, Male Urogenital Diseases, Penile Diseases, Corpus Callosum Malformation
- Trial name
- NCT03463239
- Testing
- Autologous tissue engineered corpora
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Acute Spinal Cord Injury (SCI), Spinal Cord Diseases
NG004 in Incomplete Spinal Cord Injury Patients
This is a randomized, double-blind, placebo controlled, multicenter trial of NG004 in patients with acute traumatic incomplete cervical SCI.
- Conditions
- Acute Spinal Cord Injury (SCI), Spinal Cord Diseases, Spinal Cord Injuries, Trauma Nervous System
- Trial name
- SPROUT-2 (NCT07840196)
- Testing
- NG004
- Where
- 10 sites in Germany, Switzerland
- Volunteers
- 120 people
- Sponsor
- NovaGo Therapeutics AG