Clinical trials: Trauma Prevention
Hip Fractures
Fragility Fracture Integrated Rehabilitation Management (FIRM)
A number of studies for clinical pathway (CP) after hip fracture have been suggested to improve post-fracture outcome. However, CP is not carried out properly in most countries due to inadequate system and awareness, and lack of…
- Trial name
- FIRM (NCT03430193)
- Testing
- FIRM, Conventional rehabilitation
- Where
- South Korea
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Surgical Wound Infection, Infection; Cesarean Section
Antibiotics and Gut Microbiota Among Newborn Infants
Background Women undergoing Caesarean Section (CS) have an increased risk of postpartum infections compared to women undergoing vaginal delivery. In Denmark the incidence of post-CS infections is 7-10%.
- Conditions
- Surgical Wound Infection, Infection; Cesarean Section, Complications; Cesarean Section
- Trial name
- NCT02072798
- Testing
- Cefuroxime
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Odense University Hospital
Maternal Morbidity and Mortality
Creating VIP Corps to Reduce Maternal Deaths
The goal of this observational study is to create and rigorously evaluate a violence intervention and prevention corps (VIP Corps) training using a randomized controlled trial among undergraduate and professional students; and to…
- Trial name
- NCT06089109
- Testing
- The Big 3, Implementation and Effectiveness of VIP Corps Training
- Where
- United States
- Volunteers
- 598 people, healthy volunteers welcome
- Sponsor
- Ann Coker
Occupational Injuries, Occupational Exposure
The Effect of Intelligent Exercise and Ergonomic Recommendations on Surgeon Musculoskeletal Discomfort
The goal of this clinical trial is to investigate the effects of Intelligent Physical Exercise Training (IPET) and ergonomic recommendations on musculoskeletal pain among abdominal and pelvic surgeons.
- Trial name
- NCT06112106
- Testing
- Intelligent Physical Exercise Training (IPET)
- Where
- 7 sites in United States, Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Bipolar Disorder
EMDR in Adolescents With Bipolar Disorder and History of Trauma
In this research, EMDR protocol model specific for bipolar patients with a history of trauma, developed by Benedikt Ahmann et al (2017), who applies EMDR in adults with Bipolar Disorder (BD) and history of trauma will be adapted…
- Trial name
- NCT03946787
- Testing
- Eye Movement Desensitization and Reprocessing (EMDR) Therapy, Treatment as Usual
- Where
- Brazil
- Volunteers
- 82 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Radiodermatitis
Exploratory Study of Topical Norepinephrine in Breast Cancer Patients Receiving Radiotherapy
This study, a nonrandomized open-label safety and exploratory study, will evaluate the safety of topical norepinephrine in post-surgical breast cancer patients who are undergoing radiation therapy.
- Trial name
- NCT01544504
- Testing
- Norepinephrine
- Where
- United States
- Sponsor
- ProCertus BioPharm, Inc
Pressure Ulcer, Buttock
Study of TurnCare's Q-2 System on the Sacral Pressure Ulcer Prevention in High Risk Patients
This is a non-blind randomized clinical trial to determine the efficacy of the TurnCare Q2 System for the prevention of sacral region (sacral, coccygeal, and buttocks) pressure ulcers. TurnCare Q2 System has 2 main components: 1.
- Trial name
- NCT03107143
- Testing
- Q2 System
- Volunteers
- 431 people
- Sponsor
- TurnCare Inc.
Surgical Site Infections
Ampicillin/Sulbactam Versus Cefuroxime as Antimicrobial Prophylaxis for Cesarean Section
The efficacy and safety of a single dose of ampicillin/sulbactam compared to a single dose of cefuroxime at cord clamp for prevention of postcesarean infectious morbidity has not been assessed.
- Trial name
- NCT01138852
- Testing
- Ampicillin-sulbactam, Cefuroxime
- Volunteers
- 176 people
- Sponsor
- Attikon Hospital
Surgical Wound Infection
Circular pOlyethylene Drape in preVention of Surgical Site infEction: A Randomized Controlled Trial
This study is to evaluate the effectiveness of the plastic ring wound retractor to reduce the rate of surgical site infection in patients who undergo open abdomen surgery for gastrointestinal tract.
- Trial name
- COVER (NCT03170843)
- Testing
- use of plastic ring wound retractor
- Where
- 13 sites in South Korea
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Saint Vincent's Hospital, Korea
Head and Neck Carcinoma, Radiation-Induced Dermatitis
Modified Dakin's Solution in Reducing Radiation-Induced Dermatitis in Patients With Head and Neck Cancer Undergoing Radiation Therapy
This randomized phase 3 trial studies how well modified Dakin's solution works in reducing radiation-induced dermatitis, a common skin reaction to radiation therapy, in patients with head and neck cancer undergoing radiation…
- Trial name
- NCT02369835
- Testing
- Dakin's solution
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- Stanford University
Medial Tibial Stress Syndrome
Medial Tibial Stress Syndrome Prevention
This randomized controlled trial investigated whether a 10-week heavy resistance training program reduced the incidence of medial tibial stress syndrome (MTSS) in collegiate indoor track and field athletes.
- Trial name
- NCT07256808
- Testing
- Resistance Training
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rowan University
Seizures, Traumatic Brain Injury
Does Short-Term Anti-Seizure Prophylaxis After Traumatic Brain Injury Decrease Seizure Rates?
The primary objective of this study is to prospectively assess in randomized fashion whether short term anti-seizure prophylaxis in traumatic brain injured patients decreases the incidence of seizures in the early post-injury…
- Trial name
- NCT03054285
- Testing
- Levetiracetam
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Loyola University
Sports Injuries, Flexibility
THE MYOFASCIAL SYSTEM AND MINIMIZING THE RISK OS INJURY IN SPORT
The aim of the study is to evaluate the effect of myofascial self-release on muscle mechanical properties, performance, neuromuscular function, and injury risk reduction in young soccer players.
- Conditions
- Sports Injuries, Flexibility, Balance, Jumping Performance
- Trial name
- NCT06895720
- Testing
- Myofascial Self-Release
- Where
- Portugal
- Volunteers
- 65 people
- Sponsor
- Aveiro University
Traumatic Injury, Venous Thromboembolism
Evaluation of Venous Thromboembolism Prevention in High-Risk Trauma Patients
This is a pilot study to determine if anti-thrombin III (AT-III) serum concentrations differ between patients with normal versus subtherapeutic anti-Xa trough concentrations when placed on enoxaparin 30 mg twice daily for VTE…
- Trial name
- NCT02412982
- Testing
- Enoxaparin 40 mg q12h, Enoxaparin 30 mg q8h
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- University of Cincinnati
Cardiac Valve Disease, Coronary Artery Disease
The PRE-OP ENERGY Trial
The PRE-OP ENERGY Trial proposes to test the overarching hypothesis that a pre-surgery high energy diet will protect patients against organ damage during cardiac surgery with cardiopulmonary bypass.
- Conditions
- Cardiac Valve Disease, Coronary Artery Disease, Organ Failure, Multiple
- Trial name
- NCT04015973
- Testing
- High energy diet
- Where
- United Kingdom
- Volunteers
- 116 people
- Sponsor
- University of Leicester
Post-Traumatic Headache
Prazosin for Post-Concussive Headaches
Mild traumatic brain injury (mTBI) caused by blast effects of explosive devices has been called the "signature injury" of soldiers who served in the Iraq and Afghanistan conflicts.
- Trial name
- NCT02965027
- Testing
- Prazosin
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Surgical Site Infection, Antibiotic Prophylaxis
The Role of Guideline-adherent Perioperative Antibiotic Administration and the Risk of Surgical Site Infections After Non-cardiac Surgery.
This study will seek to describe current practice of antibiotic prophylaxis to identify the effect of appropriate perioperative antimicrobial coverage - specifically regarding timing, dose adjustments, and redosing - on surgical…
- Trial name
- NCT03982810
- Testing
- Antibiotics
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Burns
The Relationship of Rehabilitation Therapy Time To The Prevention of Burn Scar Contracture
This project will develop a descriptive database of patient information and patient outcomes. This database will be used to determine the association of time spent in rehabilitation and patient outcomes, to relate patient acuity…
- Trial name
- ACT (NCT01161810)
- Testing
- Routine post burn rehabilitation therapy
- Where
- 14 sites in United States
- Volunteers
- 386 people
- Sponsor
- American Burn Association
Stress Fracture, Vitamin d
The Effect of Vitamin D and Calcium Supplementation on the Prevention of Stress Fractures.
The main objective of this study is to find whether supplemental vitamin d and calcium can reduce the incidence of stress fractures in recruits.
- Trial name
- NCT05186194
- Testing
- Vitamin D, Calcium
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
Post-Traumatic Headache, Head Trauma,Closed
Galantamine in the Treatment of Post-Traumatic Headache
Most patients with CPTH present with additional major cognitive, behavioral and somatic problems. Most drugs used currently have a negative influence on cognition.
- Conditions
- Post-Traumatic Headache, Head Trauma,Closed, Retention Disorders,Cognitive
- Trial name
- NCT00219869
- Testing
- Galantamine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rapoport, Alan, M.D.
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