Clinical trials: Trauma Prevention
Constipation, Analgesia
Enteral Naloxone Versus a Traditional Bowel Regimen for the Prevention of Opioid Induced Constipation in Trauma Patients
The purpose of this study is to determine if enteral naloxone is more effective than a traditional bowel regimen in the prevention and treatment of constipation and impaired gastric motility in critically ill trauma patients.
- Trial name
- NCT00799201
- Testing
- Naloxone and Docusate
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- CAMC Health System
Cardiovascular Disease, Fractures
The International Polycap Study 3 (TIPS-3)
The randomized 2x2x2 factorial design placebo controlled trial will enroll 5000 participants (women 60 years or older and men 55 years or older) without known heart disease or prior stroke and without a clear indication or…
- Conditions
- Cardiovascular Disease, Fractures, Cancers
- Trial name
- TIPS-3 (NCT01646437)
- Testing
- Polycap, Aspirin, Vitamin D
- Where
- 9 sites in Bangladesh, Canada and 7 more
- Volunteers
- 7,793 people
- Sponsor
- Population Health Research Institute
Athletics, Wounds and Injuries
To Evaluate the Effectiveness of an Injury Prevention Program in Athletics
The practice of Athletics leads to risk of injuries: about 61 to 76% athletes will occurred at least one injury during a season.
- Conditions
- Athletics, Wounds and Injuries, Prevention Program
- Trial name
- PREVATHLE (NCT03307434)
- Testing
- Athletics Injury Prevention Program, regular training
- Where
- France
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Muscle Strength, Athletic Performance
Nordic vs Blood Flow Restriction Nordic Exercise in Elite Female Pole Vaulters
The purpose of this randomized controlled trial is to compare the effects of Nordic Hamstring Exercise (NHE) and Blood Flow Restriction-assisted Nordic Hamstring Exercise (BFR-NHE) on hamstring muscle strength, muscle morphology…
- Conditions
- Muscle Strength, Athletic Performance, Hamstring Adaptation, Sports Injury Prevention
- Trial name
- NCT07705698
- Testing
- Nordic Hamstring Exercise, Blood Flow Restriction-Assisted Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Toros University
Nurse's Role, Wound Heal
Nursing Students Education Virtual Reality Wound Care
This study is a randomized controlled trial aiming to determine the effect of pressure sore prevention education given to nursing students at a foundation university through virtual reality on student satisfaction…
- Conditions
- Nurse's Role, Wound Heal, Prevention
- Trial name
- NCT06897865
- Testing
- survey
- Volunteers
- 70 people
- Sponsor
- Ankara Medipol University
Elbow Fracture
Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma
The investigators hypothesized that radiation therapy could be safely administered acutely after elbow trauma, and it would decrease the number of patients that would require surgical excision of heterotopic ossification.
- Trial name
- ElbowHO (NCT00991887)
- Testing
- Radiation Therapy (XRT)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Acute Appendicitis, Perforated Gastroduodenal Ulcer
Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures
Aim of prospective randomized a placebo controlled study is to prove that in case of acute surgical procedure due to appendicitis, ileus of small bowel and perforation of small bowel and stomach appropriately administered…
- Conditions
- Acute Appendicitis, Perforated Gastroduodenal Ulcer, Small Bowel Obstruction
- Trial name
- NCT01524081
- Testing
- Metronidazole, Cefuroxime, Amoxicillin (+ clavulanic acid) and Fluconazole
- Where
- Czechia
- Volunteers
- 187 people
- Sponsor
- The Faculty Hospital Na Bulovce
Venous Thromboembolism
Weight Based Enoxaparin in Trauma Patients
Hospitalized trauma patients frequently suffer from blood clots in the legs or lungs. To minimize the risk of these blood clots developing, patients may be given a blood-thinner drug such as enoxaparin.
- Trial name
- WeBET (NCT01916707)
- Testing
- Dosing of enoxaparin for VTE prophylaxis
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Intermountain Health Care, Inc.
Spinal Cord Injuries, Polytrauma
Conditioning & Open-Label Placebo (COLP) for Opioid Management in Intensive Inpatient Rehabilitation
The use of the conditioning open-label placebo (COLP) paradigm will be studied as a dose extension method to lower opioid dosage in patients with spinal cord injury, polytrauma, and burn injury.
- Conditions
- Spinal Cord Injuries, Polytrauma, Burns
- Trial name
- NCT05351333
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Spaulding Rehabilitation Hospital
Mild Traumatic Brain Injury
An Intervention Program to Reduce to the Risk of Persistent Symptoms After Concussion
This study investigates how well a new therapy program prevents persistent symptoms (e.g., headaches, fatigue, irritability, etc.) after concussion.
- Trial name
- NCT00893347
- Testing
- Treatment as usual, Cognitive-behavioural therapy
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- University of British Columbia
Child, Cerebral Palsy
Prevention of Hip Displacement in Children With Cerebral Palsy in Denmark
Children with cerebral palsy have an increased risk of hip dislocation, which is a painful and severe complication of cerebral palsy.
- Conditions
- Child, Cerebral Palsy, Radiography, Hip Dislocation
- Trial name
- NCT04403178
- Testing
- Radiographic examination with a Migration of > 40 %
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Mette Røn Kristensen
Spinal Cord Injuries, Amputation, Traumatic
Treatment of Chronic Pain After Spinal Cord Injury (SCI) or Amputation
Pain is a major problem for people after spinal cord injuries and amputations. This is a study to test how pain is affected by adding methadone to a six-week program of weekly physical therapy, relaxation training and counseling.
- Conditions
- Spinal Cord Injuries, Amputation, Traumatic, Pain
- Trial name
- NCT00006448
- Testing
- cognitive therapy, Physical Therapy, Methadone
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Concussion, Head Injury Trauma
Detection and Prevention of Concussive Injuries With Smart Technology.
Concussions are consequences of inopportune interactions between an impact force and the head that causes the head (and brain) to move too rapidly. This project involves two parts. 1.
- Trial name
- NCT04946747
- Testing
- Modern microelectrical mechanical systems (MEMS) head-impact sensors, Virtual Reality (VR) Goggle Use with consistent timing of Conditioned Stimulus and Unconditioned Stimulus, Virtual Reality (VR) Goggle Use with inconsistent timing of Conditioned Stimulus and Unconditioned Stimulus
- Volunteers
- 100 people
- Sponsor
- Chi-Ming Huang
Hip Fractures, Osteoporosis
Secondary Prevention of Osteoporotic Fractures in Residents of Long-Term Care Facilities
Osteoporotic fractures of the hip are a major cause of admission to long-term care facilities. Such fractures put patients at high risk for further fractures, pain and disability.
- Trial name
- NCT00280943
- Testing
- Long-term care facilities in the intervention arm will receive education and feedback audit on performance
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Duke University
Acquired Brain Injury
A Biofeedback Intervention for the Prevention of Challenging Behaviour
This study aims to explore whether feedback from a physical monitoring device (electronic watch) to prompt patients to use an anxiety management strategy can help prevent challenging behaviour.
- Trial name
- NCT03260335
- Testing
- Anxiety management strategy
- Sponsor
- University of Glasgow
Bronchopulmonary Dysplasia
TINN2: Treat Infection in NeoNates 2
The aim of the TINN2 study is to evaluate the efficacy of azithromycin in prevention of bronchopulmonary dysplasia in preterm neonates.
- Trial name
- TINN2 (NCT02282176)
- Testing
- Azithromycin
- Where
- 16 sites in Belgium, France and 7 more
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Drug-induced Ototoxicity in Peritoneal Dialysis Patients
Prevention of Drug Induced Ototoxicity in Peritoneal Dialysis Patients by N-Acetylcysteine
The purpose of this study is to determine whether N-acetylcysteine is effective in the prevention of hearing loss in both ears due to aminoglycoside and/or vancomycine induced ototoxicity in peritoneal dialysis patients.
- Trial name
- NCT01131468
- Testing
- N-acetylcysteine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Tissue Adhesions, Surgery-Induced
Post Approval Study to Evaluate the Safety and Performance of GENTA-FOIL Resorb® in Hand Surgery
Single arm study to evaluate the safety and performance of Genta-Foil resorb® for the prevention of tissue adhesions
- Trial name
- NCT04482140
- Testing
- Genta-Foil resorb®
- Where
- 3 sites in Greece, United Kingdom
- Volunteers
- 15 people
- Sponsor
- Advanced Medical Solutions Ltd.
Hamstring Tightness, Hamstring Injury Prevention
Effects of Neurodynamic Sliding Versus Eccentric Training on Lower Extremity Function, Strength and Proprioception in Athletes with Short Hamstring Syndrome.
Hamstring strains are among the most common injuries in field sports, accounting for 10% of all team sports injuries and often leading to long-term absence from activities.
- Trial name
- NCT06748560
- Testing
- Neurodynamics, Eccentric training
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Yeditepe University
Pressure Injury, Skin Lesions
Paraffin Oil for Preventing Tourniquet-Related Skin Lesions in Upper Extremity Surgery
This randomized controlled trial aims to evaluate the effectiveness of topical paraffin oil application in preventing tourniquet-related skin lesions in patients undergoing upper extremity surgery.
- Conditions
- Pressure Injury, Skin Lesions, Skin Injury
- Trial name
- PARA-TOUR (NCT07523958)
- Testing
- Paraffin Oil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul Medipol University Hospital
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