Clinical trials: Trauma Prevention
Medical Thoracoscopy
Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy
Medical thoracoscopy is the preferred procedure for performing pleural biopsy in patients with pleural effusions that remain undiagnosed after pleural fluid analysis.
- Trial name
- CAPTAIN (NCT05430308)
- Testing
- Chlorhexidine scrub, Povidone-iodine
- Where
- 2 sites in India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Post-Extubation Laryngeal Edema
Prevention of Post-Extubation Laryngeal Edema With Intravenous Corticosteroids
Tracheal intubation is a frequent procedure in intensive care units (ICU). Post-extubation laryngeal edema is a frequent complication with potential morbidity and mortality, and may lead to urgent tracheal re-intubation.
- Trial name
- NCT00199576
- Testing
- Methylprednisolone
- Where
- 15 sites in France
- Volunteers
- 670 people
- Sponsor
- University Hospital, Limoges
AODD and AODR Disorder
The Efficacy of Brief Motivational Interviewing for Trauma Patients Related to Alcohol or Other Abuse Drugs.
The purpose of this study is to determine whether the Brief Motivational Interview will produce a significantly reduction in risk behavior than usual treatment 3 months after discharge from hospital in people who have survived a…
- Trial name
- MOTIVA (NCT02159391)
- Testing
- Brief Motivational Interview
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
ACL Injuries
Plyometric Training With or Without Hamstring Strengthening for Preventing ACL Injuries in Female Amateur Athletes
This randomized controlled trial explored the effect of plyometric training with or without hamstring strengthening in preventing anterior cruciate ligament (ACL) injuries among female amateur athletes aged 18 to 30.
- Trial name
- NCT07047833
- Testing
- Plyometric Training with Hamstring Strengthening, Plyometric Training Only
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- University of Lahore
COVID, Coronavirus
Coronavirus Induced Acute Kidney Injury: Prevention Using Urine Alkalinization
Our overarching goal is to improve the outcomes of critically ill COVID-19 patients with or at risk for development of acute kidney injury (AKI).
- Conditions
- COVID, Coronavirus, Coronavirus Infection, AKI
- Trial name
- NCT04530448
- Testing
- Sodium bicarbonate, Standard of Care
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- West Virginia University
Fractures, Osteoporosis
Effectiveness of an Educational Program in the Prevention of Osteoporosis and Fractures
The study will elucidate the effectiveness of an educational program in the prevention of osteoporosis and fractures. A random sample of the female population in Southern Finland (Uusimaa region) within the age group of 60-70…
- Trial name
- NCT00589615
- Testing
- multidisciplinary osteoporosis prevention educational program
- Where
- Finland
- Volunteers
- 2,181 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Hypertrophic
A Study of a Novel Silicone Dressing to Minimize Scar Formation
Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a…
- Trial name
- REFINE (NCT01399099)
- Testing
- embrace device
- Where
- 13 sites in United States
- Volunteers
- 67 people
- Sponsor
- Neodyne Biosciences, Inc.
Adjustment Disorders
Learning How to Recover From Stress - Pilot RCT
This randomized, controlled pilot trial evaluated the efficacy of a brief internet-based recovery training intervention targeting distressed employees.
- Trial name
- NCT05220592
- Testing
- Internet-based recovery training program
- Where
- Sweden
- Volunteers
- 69 people
- Sponsor
- Linkoeping University
Ankle Injuries, Ankle Sprains
Foam Rolling and Tissue Flossing of the Cuff Muscles
The hypothesis is that self-myofascial release (SMR) intervention on the cuff muscles would affect positively sprint performance and jump height, as well as, decrease Achilles tendon stiffness.
- Trial name
- NCT04367532
- Testing
- Foam rolling, Tissue flossing
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wroclaw University of Health and Sport Sciences
Falls Among Older Adults
Senior Falls Prevention Study
The purpose of this study is to evaluate the effectiveness of a best practice model for senior falls prevention when implemented in a community setting.
- Trial name
- NCT00126152
- Testing
- Exercise, education and medical management
- Where
- 2 sites in United States
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Washington State, Department of Health
Vascular Disease, Surgery
Clinical Trial of a Silver Eluting Dressing System
This prospective, multi-institutional randomized clinical trial of a silver ion eluting dressing material compared to standard dry gauze for closed skin incisions after open surgical revascularizations for peripheral vascular…
- Trial name
- SILVER (NCT01229358)
- Testing
- Surgical dressing
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Brigham and Women's Hospital
Symptomatic Neuroma, Morton's Neuroma
Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain
Comparing safety, pain, user experience, healthcare economic costs, work productivity, impairment and quality of life outcomes between Axoguard® Nerve Cap and neurectomy in the treatment of symptomatic neuromas in the foot or…
- Conditions
- Symptomatic Neuroma, Morton's Neuroma, Chronic Nerve Pain
- Trial name
- REPOSE (NCT03940963)
- Testing
- AxoGuard® Nerve Cap, Standard Neurectomy
- Where
- 11 sites in United States
- Volunteers
- 86 people
- Sponsor
- Axogen Corporation
Neuropathy, Nerve Injury
Detection and Prevention of Nerve Injury in Shoulder Arthroplasty Surgery
Up to 5% of total shoulder arthroplasty patients experience transient or permanent nerve injury during surgery. In this study, we will monitor the nerve transmission of the patients' arm to detect whether the nerve is functioning…
- Trial name
- NCT03624426
- Testing
- Automated Somatosensory Evoked Potential device (EPAD@)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Premalignant Vulvar Lesion, Benign Vulvar Lesion
Does Antibiotic Prophylaxis Reduce Wound Complications After Vulvar Excision of Premalignant Lesions
A randomized control trial will provide the most reliable data to determine the role of prophylactic antibiotics to decrease the wound complication rate.
- Trial name
- NCT03578965
- Testing
- Cefazolin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Washington University School of Medicine
Epilepsy, Bone Loss
Antiepileptic Drugs and Osteoporotic Prevention Trial
Study Design: (e.g., Controlled, Double-Blind, Randomized, Parallel): Randomized, double-blind, placebo controlled of a bisphosphonate in the prevention of bone loss associated with the use of antiepileptic drugs.
- Conditions
- Epilepsy, Bone Loss, Osteoporosis, Fractures
- Trial name
- ADOPT (NCT00869622)
- Testing
- Risedronate
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Boston VA Research Institute, Inc.
Acute Kidney Failure
Ioxaglate Versus Iodixanol for the Prevention of Contrast-induced Nephropathy in High-risk Patients (IDPC Trial)
Contrast media-induced nephropathy following diagnostic and therapeutic cardiac catheterization.
- Trial name
- IDPC (NCT02991742)
- Testing
- contrast media
- Volunteers
- 2,262 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Surgical Site Infection, Anastomotic Leak
Oral Antibiotic Prophylaxis in Colorectal Surgery
The investigators perform a case-control study to compare preparation before elective colorectal surgery. The first group is a prospective patient - registry in all patients with mechanical bowel preparation (MBP) and oral…
- Trial name
- ABCR (NCT03759886)
- Testing
- Paromomycin Sulfate Powder
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Leipzig
Falls, Falls Injury
EXpress Prevent Rural oldEr Adults' fallS, fractureS and Dependency (EXPRESS)
Falls are the leading cause of injury-related death among individuals aged 65 and above in China. The incidence of falls shows a significant urban-rural disparity in China, with rural areas experiencing a markedly higher rate…
- Conditions
- Falls, Falls Injury, Fall Prevention
- Trial name
- EXPRESS (NCT06984978)
- Testing
- AI-assisted, village doctors and express services-involved personalized fall prevention strategy
- Where
- China
- Volunteers
- 1,881 people, healthy volunteers welcome
- Sponsor
- Peking University
Shoulder Injury
Shoulder Injury Prevention Program in Swimmers
The primary purpose of this study is to assess changes in shoulder muscle strength, shoulder movement, shoulder flexibility, muscle thickness, upper arm torsion angle, and subacromial width (space where the rotator cuff muscle…
- Trial name
- NCT00998777
- Testing
- Shoulder Strengthening
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Spinal Cord Injuries
Effects of FES-Rowing in Neurological Disorders (FES-ROW)
The main objective of this project is to measure the increase in aerobic physical and metabolic capacities with a 6-month training on a rower assisted by electrostimulation of lower limbs in a population of adults with traumatic…
- Trial name
- FES-ROW (NCT04821635)
- Testing
- Rower assisted by electrostimulation (FES-ROW)
- Where
- 2 sites in France
- Sponsor
- UGECAM Rhône-Alpes
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