Clinical trials: Trauma Wounds
Rotator Cuff Injury, Pain
Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene Block
Arthroscopic shoulder rotator cuff repair and acromioplasty are associated with severe postoperative pain. The interscalene block (ISB) is commonly used for this type of surgery, providing analgesia by anesthetizing the nerves…
- Trial name
- NCT02939209
- Testing
- Hydromorphone Hcl 2Mg Tab
- Where
- 2 sites in Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Vishal Uppal
Concussion Injury of Cerebrum, Cranial Osteopathic Medicine
Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion
Patients who have concussions exhibit an array of symptoms, also known as post-concussive symptoms, including headaches, feeling slowed down or foggy and difficulty with concentration.
- Trial name
- NCT03225599
- Testing
- Cranial Osteopathic Manipulative Medicine
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Cholecystectasia, Wound Heal
Infrared LED Lighting Application and Wound Healing
Laparoscopic cholecystectomy is a commonly used procedural procedure for removal of the gallbladder. Following this healing, wound healing, scar formation and scar tissue formation are critical factors in the healing process.
- Conditions
- Cholecystectasia, Wound Heal, Scar
- Trial name
- NCT06533072
- Testing
- The group receiving infrared LED therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ardahan University
Healthy
Assessment of the Wound Healing Efficacy and Tolerance of a Medical Device on Wounds in Healthy Subjects.
The tested medical device is indicated for the treatment of wounds and small skin injuries. The intention of this study is to evaluate the tolerance and efficacy of the test product by measuring the recovery of the skin barrier…
- Trial name
- NCT04687839
- Testing
- Induction of suction blister, Transepidermal water loss (TEWL), Macrophotography
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Brain Concussion
Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion
Previous research and position statements have outlined the necessity of balance and gait testing in the post-concussion evaluation of athletes.
- Trial name
- NCT02317107
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Patient Satisfaction, Surgical Wound
Sub vs Trans-umbilical Incision: A Patient's Satisfaction-centered Trial
While some studies have suggested that subumbilical and transumbilical incisions have a similar clinical efficiency and safety, no study has yet evaluated their respective impact on patient's postoperative aesthetic satisfaction.
- Conditions
- Patient Satisfaction, Surgical Wound, Incision, General Surgery
- Trial name
- NCT03026400
- Testing
- Transumbilical incision, Subumbilical incision
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Trauma, Rehabilitation
NMES and Pelvic Fracture Rehabilitation
Objectives: The acute care of pelvic fractures has improved recently however there are no formal guidelines for rehabilitation of these types of fractures. Patients have long periods of non-weight bearing causing muscle wastage.
- Trial name
- NCT03278834
- Testing
- Neuromuscular muscle stimulation machine- Strength Setting, Neuromuscular muscle stimulation machine - TENS Setting
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Acquired Brain Injury
Development of a Soft Robotic Device for Rehabilitation and Assistance of the Upper Limb for People With Neurological Disorders
Development of a soft robotic device for rehabilitation and assistance of the upper limb for people with neurological disorders (FRONTIER)
- Trial name
- FRONTIER (NCT07750314)
- Testing
- FRONTIER Soft Exoskeleton
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Brain Concussion, Posttraumatic Stress Disorder
Brain Injury Outcomes (BIO) Study
Many active duty military, national guard, and reserves personnel who served in the recent conflicts in Afghanistan and Iraq were exposed to blasts and other mechanisms of traumatic brain injury (TBI).1,2 Although physical trauma…
- Conditions
- Brain Concussion, Posttraumatic Stress Disorder, Dementia
- Trial name
- BIO (NCT00724607)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy
Naturally Produced Cannabinoids for Neuroprotection From Concussion
The goal of this double-blind, placebo-controlled, cross over study is to learn about the neuroprotective properties of a broad-spectrum cannabinoid formulation in normal healthy adults engaged in elite contact sport competition.
- Trial name
- NCT07715864
- Testing
- Broad spectrum cannabinoid formulation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Regina
Shoulder Dislocation, Bone Loss
Latarjet vs Anatomic Glenoid Reconstruction
Anterior shoulder dislocations occur when the humeral head translates anterior to the glenoid cause pain, stiffness, and glenoid bone loss. If left untreated, the risk of recurrence can be up to or greater than 90%.
- Conditions
- Shoulder Dislocation, Bone Loss, Arthroscopy
- Trial name
- NCT05658289
- Testing
- Coracoid Transfer, Distal Tibia Allograft with Bankart repair
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Brain Concussion
Effect of Soccer Head Gear to Reduce Concussions
This study will determine if protective soccer headgear reduces the incidence or severity of Sport Related Concussion injuries (SRCs) in US adolescent (high school) soccer players.
- Trial name
- Socheadgear (NCT02850926)
- Testing
- Soccer head gear
- Where
- United States
- Volunteers
- 3,050 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Pitch, Baseball Pitcher
OMT for Overhead Throwing Performance: A Study on Shoulder and Hip Interventions
To investigate the impact of manual medicine on key aspects of the kinetic chain on measures of performance in collegiate baseball players.
- Conditions
- Pitch, Baseball Pitcher, Throwing Performance
- Trial name
- NCT07878650
- Testing
- Osteopathic Manipulative Treatment
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- William Carey University
Mild Traumatic Brain Injury, Post-Concussive Symptoms
Consistency of Automated Neuropsychological Assessment Metrics (ANAM) Performance in Those With Deployment Acquired Mild Traumatic Brain Injury (TBI)
The purpose of this project is to explore the degree to which performance consistency on neuropsychological measures varies in a sample of Operation Iraqi Freedom (OIF)/Operation Enduring Freedom (OEF) Veterans with a history of…
- Trial name
- ANAM (NCT01334528)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Orbital Fractures
Using the Transconjuctival Approach Alone Versus Using it Together With Lateral Canthotomy in Orbital Fractures
All cases will undergo surgery under general anesthesia. Evaluation of patients with suspected orbital fracture should involve radiologic examination, motility test, diplopia field test and exophthalmometry.
- Trial name
- NCT03813732
- Testing
- orbital fracture
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bites and Stings
Field Evaluation of Two Topically Applied Insect Repellent Products Containing IR3535 Against Mosquitos in Louisiana
To determine the efficacy and duration of protection of two topically applied insect repellent products at preventing landing by mosquitos. The study will follow the EPA Product Performance Test Guidelines1.
- Trial name
- NCT05394597
- Testing
- Repellent lotion, Repellent Wipe
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Tendon Injury - Hand
Tranexamic Acid Effect on Digit Function Following Primary Repair of Traumatic Digit Flexor Tendon Injuries
This study evaluates the effect of pre-operative treatment with IV Tranexamic Acid on post-operative digit function, in patients that underwent surgical repair of traumatic zone 1 or zone 2 digit flexor tendon tear.
- Trial name
- NCT04178655
- Testing
- Tranexamic acid injection
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Healing Wound, Iron-deficiency
Impact of Iron Stores on Wound Healing in Plastic Surgery
In breast reduction surgery, delayed wound healing may increase surgical site infections, cutaneous necrosis and may be related to psychological harm.Some risk factors have been identified : smoking, diabetes, overweight.
- Conditions
- Healing Wound, Iron-deficiency, Surgical Wound
- Trial name
- IRONPLAST (NCT04276168)
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Traumatic Brain Injury, Concussion
Enhancing Cognitive and Neurobehavioral Functions After Repetitive Traumatic Brain Injuries (rTBI) in Retired NFL Players and Military Veterans.
The purpose of this study is to compare different combinations of cognitive training in retired professional football players and military veterans with a history of repeated concussions and persistent symptoms of impaired…
- Conditions
- Traumatic Brain Injury, Concussion, Mild Cognitive Disorder
- Trial name
- NCT02699476
- Testing
- Psycho-Social Therapy, Cognitive Behavioral Computer Training, Interactive Trainer-Subject Sessions
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brain & Body Health Foundation
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