Clinical trials: Trauma and Stress Related Disorders
Stress, Psychological, Stress Disorders, Traumatic
Promoting Resiliency in Veteran Families With Young Children
Family-centered prevention services for civilian dwelling military (CDM) families \& children are rarely available in civilian communities or often framed around mental disorders and family deficits.
- Conditions
- Stress, Psychological, Stress Disorders, Traumatic, Regulation, Self, Behavior, Child
- Trial name
- FOCUS-EC (NCT04598100)
- Testing
- FOCUS-EC
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
PTSD
Primary Care-Based Mindfulness Intervention for Veterans With PTSD
Primary care patients typically do not receive adequate PTSD treatment because of their reluctance to engage in empirically-supported treatments offered in specialty care settings.
- Trial name
- NCT02399696
- Testing
- Primary Care-Brief Mindfulness Program, Primary Care-Treatment as Usual
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
Prolonged Grief Disorder
Iyengar Yoga for Prolonged Grief Disorder
Experiencing the death of a loved one is inevitable for older adults. Before the coronavirus disease 2019 (COVID-19) pandemic, over 2.5 million people died annually in the United States, including 52,000 in Wisconsin alone, and…
- Trial name
- Yoga (NCT05026827)
- Testing
- Iyengar Yoga, Socialization Control
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Post Traumatic Stress Disorder
Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD
The goal of this exploratory, mixed-method design study is to gather qualitative and quantitative data obtained through interviews and questionnaires with veterans who are currently enrolled at the VA for healthcare.
- Trial name
- PMATAVP (NCT05895318)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Albany Research Institute, Inc.
Stress, Stress Disorders
Manage Your Workingnegative Thoughts Through Hypnosis
Medical doctor generally are exposed to several risks and pressures, it is not a case that several meta-analyses have shown high stress and anxiety level in these workers. Stress management represents a very important topic.
- Trial name
- Hypnosis (NCT06778109)
- Testing
- Experimental: Hypnosis and negative memory
- Where
- 2 sites in Italy
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Padova
Post-traumatic Stress Disorder (PTSD), Trauma
Functional Brain Imaging in PTSD
Patients with post-traumatic stress disorder (PTSD) have abnormalities in the function of the amygdala and medial prefrontal cortex (particularly anterior cingulate), in addition to abnormalities of hippocampal volume.
- Trial name
- NCT02053532
- Testing
- Positron emission tomography/magnetic resonance imaging
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Posttraumatic Stress Disorder
Measurement of Pituitary Volume and Hormonal Changes in Patients With Post-traumatic Stress Disorder
Approximately, post-traumatic stress disorder (PTSD) occurs in 8% of the adult population over time. Exposure to traumatic events increases the risk of poor physical health and often leads to disability.
- Trial name
- NCT00815204
- Testing
- MRI of the pituitary, DEX/CRH test
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Mental Health Issue, Mental Stress
"OnCall": Implementation Study of M-Health for Canadian Public Safety Personnel
First Responders, or Public Safety Personnel (PSP), play a key role in protecting the health and safety of Canadians, yet this important work can take a toll on their mental health, leading to an elevated risk of post-traumatic…
- Conditions
- Mental Health Issue, Mental Stress, Post Traumatic Stress Disorder
- Trial name
- OnCall (NCT05255419)
- Testing
- OnCall mobile health peer support app
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- McMaster University
Moral Injury, Perceived Stress
Role Model-Based Ethics Education and Moral Injury Prevention in Second-Year Medical Students
This study examines whether role model-based ethics education can reduce moral injury and perceived stress, and improve resilience, among second-year medical students in Taiwan.
- Conditions
- Moral Injury, Perceived Stress, Resilience, Ethics Education
- Trial name
- NCT07656402
- Testing
- Role Model-Based Ethics Education (Standard Intensity), Role Model-Based Ethics Education (Enhanced Intensity)
- Where
- Taiwan
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Chun Lun Hsu
Stress Disorders, Post-Traumatic
Gene Expression Correlates of Post-Traumatic Stress Disorder (PTSD) Symptom Change After EFT (Emotional Freedom Techniques)
The purpose of the study is to measure the change in psychological symptoms and gene expression in war veterans after a series of 10 EFT coaching sessions.
- Trial name
- NCT01250431
- Testing
- EFT (Emotional Freedom Techniques)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Soul Medicine Institute
Stress Disorders, Post-Traumatic
Real-time fMRI and Neurofeedback of Brain Networks Mediating Trauma Memory Recall in PTSD
The purpose of the current study is to develop a better understanding of the brain mechanisms involved in psychological treatments for posttraumatic stress disorder (PTSD).
- Trial name
- NCT02500719
- Testing
- Computational Model - Real-time Support Vector Machine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Psychological Distress, Psychological Trauma
Self Help Plus and Post-Migration Living Difficulties Support Intervention
This study will conduct a two-arm, single-blind, randomized controlled trial among Syrian refugee women living in Turkey who experience psychological distress.
- Conditions
- Psychological Distress, Psychological Trauma, Mental Health, Refugee Health
- Trial name
- NCT06467071
- Testing
- SH+ combined with a session for PMLD
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Medipol University
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Posttraumatic Stress Disorder, Tinnitus
Neurobiological Similarities of Tinnitus and PTSD
Psychiatric distress caused by PTSD may increase attention toward tinnitus, as well as perceived loudness and discomfort. It is important to understand how tinnitus-related distress and PTSD negatively interact together, in order…
- Trial name
- NCT05981391
- Testing
- resting-state functional MRI, Clinician Administered PTSD Scale for the DSM-5 (CAPS-5), Tympanometry
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post-Traumatic Stress Disorder (PTSD), Depression
Transforming Trauma Care
This study evaluates the implementation and clinical effectiveness of the Trauma Resilience and Recovery Program (TRRP 2.0), a technology-enhanced behavioral health intervention designed for trauma center patients.
- Conditions
- Post-Traumatic Stress Disorder (PTSD), Depression, Substance Use Disorder, Traumatic Injury
- Trial name
- NCT07829510
- Testing
- Trauma Resilience and Recovery Program Portal 2.0 (TRRP 2.0)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
PTSD, Anxiety
Exploring Medically Perceived Benefits, Use and Interest in Psychedelics and Cannabinoids
The primary objective of this study is to collect insights from first responders and military personnel on their need for, use of, and interest in physical and/or mental health medical marijuana or psychedelic-assisted therapy…
- Conditions
- PTSD, Anxiety, Anxiety Disorders, Depression
- Trial name
- EMPOWER (NCT04965740)
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Empower Research Inc
Peripheral Vascular Diseases
Examining the Impact of Exercise Training on Vascular Dysfunction in Individuals With Mental Health Disorders - Study 3
The purpose of this research study is to examine the effect of various forms of exercise training on blood vessel function in healthy individuals as well as individuals with mental health disorders (posttraumatic stress disorder…
- Trial name
- NCT04916340
- Testing
- Muscular Strength Training Group, Muscular Fitness Training Group
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Ptsd
PTSD Interview Regarding Future Study Design and Equipment.
To gain insight and perspective unique to individuals with a diagnosis of PTSD, this study will utilize an experiential one-to-one interview format.
- Trial name
- NCT05276115
- Testing
- Interview
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Life University
PTSD
Prevention of Combat-related PTSD Using Attention Bias Modification (ABM): A Randomized Controlled Trial
Military deployment to combat zones involves exposure to trauma at a higher than average rate and therefore presents a unique opportunity to study predisposing factors to posttraumatic stress reactions and test strategies…
- Trial name
- NCT01723215
- Testing
- Active ABMT8, Active ABMT4
- Where
- Israel
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University