Clinical trials: Trauma and Stress-related Disorders
Depression, Post-Traumatic Stress Disorder
Depression Screening in Primary Care: Using HIT for Patients With Limited English
This study assessed the potential of Health Information Technology (HIT) to improve the screening, diagnosis, and treatment of depression and post-traumatic stress among LEP Southeast Asians.
- Trial name
- NCT03191929
- Testing
- HIT Intervention, Minimal Intervention Control Arm
- Volunteers
- 410 people
- Sponsor
- Dara Sorkin
Posttraumatic Stress Disorder
Prolonged Exposure Versus Treatment as Usual in Chronic Posttraumatic Stress Disorder Combat and Terror Related Patients
Assessing the efficacy of Posttraumatic Stress Disorder (PE) treatment for chronic Posttraumatic Stress Disorder (PTSD)
- Trial name
- NCT00229372
- Testing
- Prolonged Exposure (PE) therapy
- Where
- Israel
- Sponsor
- Sheba Medical Center
Mother-child Relations, Parenting
Project BELONG: Breaking the Cycle of Intergenerational Family Violence and Trauma
This study will examine the efficacy of a dyadic therapy intervention for mothers who have histories of adverse events (e.g., history of family violence, partner violence, family conflict, and/or childhood trauma, including…
- Conditions
- Mother-child Relations, Parenting, Parent Child Abuse, Family Conflict
- Trial name
- NCT03212339
- Testing
- Therapeutic intervention
- Where
- United States
- Sponsor
- Boston Medical Center
PTSD - Post Traumatic Stress Disorder
Transcranial Magnetic Stimulation in Veterans With PTSD
With this research investigators hope to begin to understand how rTMS can improve posttraumatic stress disorder (PTSD) symptoms.
- Trial name
- NCT07336251
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- White River Junction Veterans Affairs Medical Center
Posttraumatic Stress Disorder
MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD
The goal of this clinical trial is to learn if cognitive-behavioral conjoint therapy (CBCT) in combination with MDMA-assisted therapy is safe and effective in people with chronic PTSD and their partners.
- Trial name
- NCT02876172
- Testing
- MDMA, CBCT, Therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Resilient Pharmaceuticals
Orthopedic Trauma Surgery Patients, Postoperative Pain
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma.
- Conditions
- Orthopedic Trauma Surgery Patients, Postoperative Pain, Opioid Use, Depression
- Trial name
- NCT06903819
- Testing
- Ketamine, standard general anesthesia
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Texas Tech University Health Sciences Center
Post-traumatic Stress Disorder
Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People
The clinic of psychological trauma in adolescents still requires further development, whereas it is well documented in adults. This clinic is complex, because it must take into account the nature and type of trauma (recent or…
- Trial name
- TRAUMADOPSY (NCT06138522)
- Testing
- Semi-structured interviews, Child Post-Traumatic Stress Response Index (CPTS-RI) scale, - Therapeutic Alliance Questionnaire (HAQ-CP)
- Where
- France
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Traumatic Stress Disorder, Cancer
Narrative Exposure Therapy to Reduce Symptoms of Traumatic Stress in Cancer Survivors
The main purpose of the study is to evaluate the feasibility, acceptability, and potential effectiveness of NET in reducing symptoms of traumatic stress (e.g., hyperarousal, avoidance, and intrusion) in cancer patients who are…
- Trial name
- NCT05272553
- Testing
- Narrative Exposure Therapy
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Stress Disorders, Post-Traumatic
Feasibility of a Yoga Program for Veterans With PTSD
This study is designed to examine the feasibility of a 12-week yoga program on physiological and psychological health and its neurobiological mechanisms in N=15 veterans with posttraumatic stress disorder (PTSD).
- Trial name
- NCT05177757
- Testing
- Yoga Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Marquette University
PTSD, Cardiovascular Disease
Lifestyle and Cardiometabolic Risk in Post-9/11 Veterans
Heart disease and diabetes are leading causes of death and disability in the US, especially among Veterans. Posttraumatic stress disorder (PTSD) is a disabling condition that also affects many Veterans.
- Conditions
- PTSD, Cardiovascular Disease, Metabolic Syndrome
- Trial name
- NCT04911153
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Anxiety
Self-Defense Training in Women With Trauma
Previous research has shown that self-defense training can lead to gains in women's assertiveness, self-esteem, self-efficacy, and physical competence, and decreases in anxiety, helplessness, fear, and avoidant behaviors.
- Conditions
- Depression, Anxiety, Stress Disorders, Post-Traumatic
- Trial name
- NCT01380379
- Testing
- Life skills and self-defense training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Stanford University
PTSD, Depression
Trauma and Truth Interventions (NET) Versus Conflict Resolution and Social Skills Trainings for Vulnerable Youths in Northern Uganda
More than 300,000 children are fighting in armed conflicts all over the world. In Uganda an estimated number of 25,000 children have been abducted and forced to fight or work as porters and sex slaves on the side of the rebels…
- Conditions
- PTSD, Depression, Aggression
- Trial name
- NCT00893750
- Testing
- NET Truth Education, Conflict Resolution and Social Competence Skills, Traditional Ways of Coping
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
Post Traumatic Stress Disorder
A Study to Assess the Use of Methylone in the Treatment of PTSD
This study is evaluating the safety, tolerability, and efficacy of methylone in adults with PTSD. The study will be conducted in two parts.
- Trial name
- IMPACT-1 (NCT05741710)
- Testing
- Methylone
- Where
- 16 sites in United States, Ireland and 1 more
- Volunteers
- 79 people
- Sponsor
- Transcend Therapeutics
PTSD
Narrative Exposure Therapy Study for PTSD Among the Homeless Population
The purpose of this study is to assess the acceptability and feasibility of delivering Narrative Exposure Therapy to homeless individuals with Post-Traumatic Stress Disorder.
- Trial name
- NCT03781297
- Testing
- Narrative Exposure Therapy, Genealogical Services
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Ottawa
Post-Traumatic Stress Disorder
BRL29060A (Paroxetine Hydrochloride Hydrate) in Posttraumatic Stress Disorder
This was a 52-week, non-comparative, uncontrolled study of paroxetine in Japanese PTSD patients to obtain clinical experience regarding efficacy and safety.
- Trial name
- NCT00839397
- Testing
- Paroxetine
- Volunteers
- 52 people
- Sponsor
- GlaxoSmithKline
Stress Disorders, Post-Traumatic, Anxiety
Diaries for Critically Ill Patients Written by Relatives
This study will investigate the effect of diaries written by relatives for critically ill patients on the risk of posttraumatic stress symptoms.
- Conditions
- Stress Disorders, Post-Traumatic, Anxiety, Depression
- Trial name
- NCT02357680
- Testing
- Diary
- Where
- 2 sites in Denmark
- Volunteers
- 189 people
- Sponsor
- Hospitalsenheden Vest
Post-Traumatic Stress Disorder
Brief Cognitive-Behavioral Treatment for Victims of Mass Violence
The objective of this randomized control trial is to compare the effectiveness of Stress Inoculation Training (SIT), a well researched psychological treatment for Post Traumatic Stress Disorder (PTSD), to that of the non-specific…
- Trial name
- NCT00495027
- Testing
- Internet-delivered Stress Innoculation Training
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University
PTSD, Post Traumatic Stress Disorder
Diet Induced Ketosis for Patients With Posttraumatic Stress Disorder (PTSD), a Feasibility Study
Many patients suffering from posttraumatic stress disorder (PTSD) are resistant to established treatment consisting of psychotherapy.
- Trial name
- NCT05415982
- Testing
- Ketogenic Diet
- Where
- Norway
- Volunteers
- 3 people
- Sponsor
- Jens Rikardt Andersen
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans 3.0
Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Hypertension
- Trial name
- EMPOWER (NCT07356479)
- Testing
- EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Psychological Trauma, Historical, Discrimination, Racial
The Social Regulation of Threat-related Vigilance and Arousal
This study will examine the effects of social support on threat vigilance and arousal using eye tracking. We will also test the moderating effects of trauma and discrimination history.
- Conditions
- Psychological Trauma, Historical, Discrimination, Racial, Emotion Regulation, Social Interaction
- Trial name
- NCT05558527
- Testing
- social support
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
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