Clinical trials: Traumatic Amputation
Amputation; Traumatic, Hand
Validation of Point Partial User Needs With Partial Finger Amputees
The objective of the device feasibility study will be to validate the user needs of the Point Partial system. This study will be a single group intervention model where one group of 5 partial finger amputees will be asked to…
- Trial name
- NCT05012657
- Testing
- Point Partial
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Point Designs
Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion
Central Programming in Patients With a Bionic Hand After Traumatic Brachial Plexus Injury
Traumatic brachial plexus lesions may lead to permanent impairment of hand function despite brachial plexus surgery. In selected cases the affected forearm can be amputated and replaced by a bionic hand.
- Conditions
- Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion, Bionic Hand Reconstruction
- Trial name
- NCT04649749
- Testing
- MRI
- Where
- Austria
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Wounds and Injuries, Traumatic Amputation
Monitoring and Treatment of Extremity Trauma for Mass Casualties in Difficult Contexts
The prospective cohort study, SuTra2, assesses the functional and socio-economic status of patients who were operated on for a severe limb injury resulting in amputation or limb preservation 1 and 2 years after the 2010 Haiti…
- Trial name
- SuTra² (NCT01779011)
- Where
- Haiti
- Volunteers
- 305 people
- Sponsor
- Alliance for International Medical Action
Traumatic Amputation of Lower Extremity
Effects of Wearing a Powered Ankle-Foot Prosthesis on Amputee Walking
Amputees wearing a conventional prosthesis require 20-30% more metabolic energy to walk at the same speeds as non-amputees and this discrepancy is more apparent at faster walking speeds.
- Trial name
- NCT00869947
- Testing
- Powered ankle-foot prosthesis, No device
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Amputation; Traumatic, Hand
Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization
The purpose of this study is to determine the effectiveness of therapeutic dose intravenous heparin at improving replantation/revascularization success and its indications (if any) in participants who have suffered traumatic…
- Trial name
- NCT04725201
- Testing
- Intravenous unfractionated heparin
- Where
- Canada
- Volunteers
- 188 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lower Limb Amputees
Impact of Exercise Medicine on Lower Limb Amputees According to the International Classification of Functioning
The purpose of this study is to determine whether exercise medicine in lower limb amputees has a impact on the three domains of the International Classification of Functioning of the WHO (function, activities and participation)…
- Trial name
- NCT02297295
- Testing
- Physiotherapy
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Prosthesis, Lower Limb Amputation Knee
Clinical and Functional Assessment of Patients With Transfemoral Amputation Treated With Osteointegrated Implant
Limb amputation is a traumatic event that significantly reduces the ability to perform daily activities, impairs mobility, and lowers quality of life.
- Conditions
- Prosthesis, Lower Limb Amputation Knee, Amputation; Traumatic, Leg, Lower
- Trial name
- OSTEO-OUTCOME (NCT06737770)
- Testing
- osseointegrated surgery for transfemoral amputation
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Amputation Stump, Amputation Neuroma
Comparison Between Digital Nerve Microanastomosis and Traction Neurectomy in Post-Digital Amputation Pain
The goal of this prospective observational study is to assess the post-operative pain in adults with digital amputation following two different surgical interventions: microanastomosis of digital nerves or traction neurectomy.
- Conditions
- Amputation Stump, Amputation Neuroma, Amputation, Traumatic/Surgery, Amputation, Surgical
- Trial name
- NCT07102654
- Volunteers
- 50 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Bilateral Traumatic Amputation of Upper Limbs
Medical Economic Evaluation of Bilateral Allograft of Hands and Forearms
The double amputation of the forearms is a rare handicap that seriously impacts the autonomy and the quality of life of patients, social and familial exclusion, and dependence on third parties for everyday activities.
- Trial name
- ARMEDIC (NCT02797457)
- Testing
- Bilateral allograft of the hands and forearms., Prosthetic forehands
- Where
- 11 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Wounds, Wounds and Injuries
Pilot Trial for WounDx™ Clinical Decision Support Tool
The purpose of this research is to evaluate the overall use of the WounDx medical device in a clinical setting, such as a hospital.
- Conditions
- Wounds, Wounds and Injuries, Extremity Injury, Traumatic Wounds and Injuries
- Trial name
- NCT06921707
- Testing
- Clinical Decision Support Tool, Standard of Care (SOC)
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Transfemoral Amputation, Unilateral Traumatic Amputation of Leg at or Above Knee
Functional Outcomes in Dysvascular Transfemoral Amputees
In older adults, poor circulation in the lower extremities leads to serious health complications including limb loss. In addition, individuals with dysvascular disease also suffer from other co-morbidities like diabetes, coronary…
- Trial name
- CLEG (NCT01537211)
- Testing
- C leg compared to subject's mechanical leg (Otto Bock)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Prosthesis User, Amputation; Traumatic, Limb, Lower
Criteria for Advanced Prosthetic Foot Prescription
The purpose of this study is to develop criteria for prosthetic foot prescription for Veterans and Service Members with transtibial limb loss.
- Trial name
- NCT03505983
- Testing
- ESR Prosthetic Foot First, Articulating ESR Prosthetic Foot First, Powered Prosthetic Foot First
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System
Amputation; Traumatic, Hand
Sensor Glove and Non-Invasive Vibrotactile Feedback Insole to Improve Hand Prostheses Functions and Embodiment
State-of-the-art myoelectric prostheses provide upper limb amputees with a remarkable variety of grip patterns but lack proper feedback from touch sensation.
- Trial name
- FeetBack (NCT03924310)
- Testing
- FeetBack System Active, FeetBack System Passive
- Where
- Switzerland
- Volunteers
- 4 people
- Sponsor
- Martin Berli
Traumatic Amputation of Lower Extremity
Characterizing Ankle Function During Sloped Locomotion for Prosthesis Development
The proposed study aims to characterize biological ankle joint function during walking and running on slopes in order to further develop advanced powered ankle-foot prostheses.
- Trial name
- NCT01784003
- Testing
- Powered ankle-foot prosthesis
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Traumatic Amputation of Arm, Traumatic Amputation of Hand
Vascularized Composite Allotransplantation of the Hand and Upper Extremity (Hand Transplant)
The Southern Illinois University (SIU) Hand Transplant Program is a multidisciplinary research effort with the goal of restoring form and function to unilateral or bilateral upper extremity amputees by vascularized composite…
- Trial name
- NCT02165865
- Testing
- upper extremity/ hand transplantation
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- Southern Illinois University
Amputation; Traumatic, Arm, Upper
Teleoperation Experimental Comparison With Able-bodied Subjects
To compare the use of the semi-autonomous control algorithm (condition 1) with the standard of care myoelectric system used with the TASKA prosthetic hand (condition 2).
- Trial name
- NCT05048394
- Testing
- Semi-autonomous myoelectric control algorithm, Standard-of-care myoelectric control algorithm
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Point Designs
Traumatic Amputation of Arm
Home Study of an Advanced Upper Limb Prosthesis
The overall study objective is to examine the feasibility, acceptance, and benefits of home use of an advanced upper limb prosthetic device as well as the logistical support requirements utilized during 3 months of home usage.
- Trial name
- NCT01551420
- Testing
- Advanced upper limb prosthetic device IMU controlled, Advanced upper limb prosthetic EMG-PR controlled
- Where
- 4 sites in United States
- Volunteers
- 52 people
- Sponsor
- VA Office of Research and Development
Amputation, Traumatic
Human Upper Extremity (Hand and Forearm) Allotransplantation
Overall Goal To establish hand transplantation as a safe and effective reconstructive strategy for the treatment of upper extremity amputations.
- Trial name
- NCT00722280
- Testing
- Hand Transplantation
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Amputation; Traumatic, Limb, Postural; Defect
Comparison of Transtibial and Transfemoral Amputees' Posture Parameters
With the onset of prosthesis use following lower extremity amputations, body shows biomechanical changes according to the amputation level and consequently develops adaptation mechanisms both on the healthy and ampute side.
- Trial name
- NCT04456244
- Testing
- Evaluation of the static posture
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Amputation, Traumatic, Wounds and Injury
Human Upper Extremity Allotransplantation: F/U Protocol
Upper extremity allotransplantation is a new procedure which is becoming more common in the United States. Ongoing data collection for research purposes is vital to the long-term assessment as to the safety of the procedure and…
- Conditions
- Amputation, Traumatic, Wounds and Injury, Hand Injuries
- Trial name
- NCT03400345
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University