Clinical trials: Traumatic Amputations
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees
The goal of this proposed project is to gather community-based data from the K4-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT05267639
- Testing
- Power Knee
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Prosthesis User, Amputation; Traumatic, Limb, Lower
Criteria for Advanced Prosthetic Foot Prescription
The purpose of this study is to develop criteria for prosthetic foot prescription for Veterans and Service Members with transtibial limb loss.
- Trial name
- NCT03505983
- Testing
- ESR Prosthetic Foot First, Articulating ESR Prosthetic Foot First, Powered Prosthetic Foot First
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA New York Harbor Healthcare System
Phantom Limb
Study to Identify the Genetic Variations Associated With Phantom Limb Pain
The purpose of this study is to determine if there is a genetic component to phantom limb pain. DNA will be analyzed for single nucleotide polymorphisms (SNPs) between the control and phantom limb pain group.
- Trial name
- NCT01462448
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Amputation, Amputation, Traumatic
GaMA Metric to Quantify Functional Importance of Various Upper Limb Prosthetic Devices
The goal of this study is to utilize the Gaze and Movement Assessment (GaMA) metric to assess the effect of different prosthetic components on compensatory movements used to complete activities of daily living.
- Conditions
- Amputation, Amputation, Traumatic, Amputation; Traumatic, Hand, Amputation; Traumatic, Limb
- Trial name
- NCT06420687
- Testing
- Clinically prescribed prosthesis, Experimental prosthesis - Wrist rotation + 1-DOF, Experimental prosthesis - Wrist rotation + Wrist flexion +1-DOF
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Amputation, Amputation; Traumatic, Hand
Dexterous Partial Hand Prosthesis Outcomes
Liberating Technologies, Inc. (LTI) has developed a dexterous prosthetic fingertip that will be fit onto an i-Digits™ partial hand prosthesis and allow for an additional fine grasp.
- Conditions
- Amputation, Amputation; Traumatic, Hand, Limb; Absence, Congenital, Upper, Prosthesis User
- Trial name
- NCT05038566
- Testing
- Pointdexter
- Where
- 2 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Amputation; Traumatic, Arm, Upper
Teleoperation Experimental Comparison With Able-bodied Subjects
To compare the use of the semi-autonomous control algorithm (condition 1) with the standard of care myoelectric system used with the TASKA prosthetic hand (condition 2).
- Trial name
- NCT05048394
- Testing
- Semi-autonomous myoelectric control algorithm, Standard-of-care myoelectric control algorithm
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Point Designs
Amputation, Amputation; Traumatic, Leg, Lower
Socket Cooling Effectiveness Take Home Study
The comfort and fit of the residual limb within a prosthetic socket are of primary concern for many amputees. The residual limb is typically covered by non-breathable and non- thermally conductive materials that can create a warm…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Amputation Stump, Limb; Absence, Congenital, Lower
- Trial name
- NCT04484805
- Testing
- ICE Condition
- Where
- 2 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Amputation, Traumatic
Studying Electromyographic Activity in Patients With Upper Limb Amputations
The primary purpose of this study is to determine the extent to which the Regenerative Peripheral Nerve Interface ( i.e. reinnervation of partial muscle grafts by residual peripheral nerves) enables both the generation of…
- Trial name
- NCT02956603
- Testing
- Fine wire EMG electrodes
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Amputation, Traumatic Amputation of Lower Extremity
Sitting Balance in Lower Limb Amputees
The aim of this study is to compare the sitting and standing postural stability of transfemoral individuals with healthy individuals with similar demographic characteristics.
- Trial name
- NCT05597696
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Amputation; Traumatic, Leg, Lower
Design, Prototyping, and Testing of a Robotic Prosthetic Leg
The purpose of this graduate student research study is to test that a specifically designed and novel robotic prosthetic leg (RPL) is feasible, safe and improves symmetry, efficiency, and metabolic function during sit-to-stand…
- Trial name
- NCT04616378
- Testing
- Phase 2 Prescribed Prosthesis, Phase 2 Robotic Prosthetic Leg, Phase 3 No Prosthesis
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Amputation, Traumatic, Phantom Sensation
Investigating The Effect of Phantom Sensation on Gait in Individuals With Unilateral Below-Knee Amputation
Amputation is a problem that can be encountered for many reasons, can cause functional disability in varying severities and puts a multifaceted financial burden on individuals, society, and states.
- Trial name
- NCT05177341
- Testing
- Determining Preferred Walking Speed
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trakya University
Traumatic Amputation of Lower Extremity, Cartilage Degeneration
The Assessment of Talar Cartilage in Patients With Unilateral Traumatic Transtibial Amputation
Increased risk of osteoarthritis (OA) has been previously demonstrated in patients with lower limb amputation. Although there are many studies on knee joint of intact limb of amputees in the literature, the number of studies on…
- Trial name
- NCT04486534
- Testing
- Musculoskeletal ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Amputation, Amputation; Traumatic, Hand
EMG-Based Hand-Wrist Control: Study B Mirrored
Study assessing four-channel prosthesis controller, that compares contralateral (mirrored) EMG-force training to ipsilateral EMG-target training with both limb-absent and able-bodied subjects
- Conditions
- Amputation, Amputation; Traumatic, Hand, Amputation, Congenital, Prosthesis User
- Trial name
- PSICON-B (NCT04692571)
- Testing
- PSICON Measurement Apparatus
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.
Amputation, Traumatic
Sonographic Evaluation Of Nerve Thickness In Traumatic Lower-Limb Amputees
Lower limb amputation (LLA) commonly affects young and active people who have long life expectancy. It is a major surgery causing many functional deficiencies which can reduce overall health quality and physical condition of the…
- Trial name
- NCT04602793
- Testing
- ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Traumatic Amputation of Lower Extremity
Characterizing Ankle Function During Sloped Locomotion for Prosthesis Development
The proposed study aims to characterize biological ankle joint function during walking and running on slopes in order to further develop advanced powered ankle-foot prostheses.
- Trial name
- NCT01784003
- Testing
- Powered ankle-foot prosthesis
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Amputation, Traumatic
Rectus Femoris Thickness Measurement in Unilateral Transtibial Amputated Prosthesis Users
Knee extension strengthening is one of the cornerstones of rehabilitation in prosthesis users with transtibial amputation. It is recommended in terms of increasing functional mobility, preventing the risk of fall and knee…
- Trial name
- NCT04262297
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Marmara University
Amputation, Traumatic, Traumatic Amputation of Lower Extremity
What is the Optimal Stiffness and Height of a Running-specific Prosthesis?
The proposed study aims to characterize the effects of running-specific leg prosthetic stiffness and height during on performance during running and sprinting to optimize running-specific prosthesis prescription.
- Conditions
- Amputation, Traumatic, Traumatic Amputation of Lower Extremity, Wounds and Injuries
- Trial name
- NCT02318979
- Testing
- Otto Bock prosthesis, Ossur prosthesis, Freedom Innovations prosthesis
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Amputation, Traumatic
Human Upper Extremity (Hand and Forearm) Allotransplantation
Overall Goal To establish hand transplantation as a safe and effective reconstructive strategy for the treatment of upper extremity amputations.
- Trial name
- NCT00722280
- Testing
- Hand Transplantation
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Traumatic Amputation of Upper Limb, Level Unspecified
Development of a Simulation Tool for Upper Extremity Prostheses
Amputees often choose not to wear prostheses due to marginal performance or may settle for a prosthesis that offers only cosmetic improvement, but lacks function.
- Trial name
- NCT01622530
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Prosthesis User, Amputation; Traumatic, Limb, Lower
Strategic Research Program 17 (VUB Funding)
Objectives: The main objectives are to determine neural dynamics during gait using electro-encephalography as well as brain sources and to investigate the attentional demand during walking in able-bodied individuals, and…
- Trial name
- NCT03498872
- Testing
- AMPfoot 4.0, No intervention
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel