Clinical trials: Traumatic Brain Injury (TBI)
Traumatic Brain Injury, Partner Caregiver
Comparison of Two Group Wellness Interventions in TBI Partner Caregivers
The purpose of this research study is to compare the effect of two different types of group wellness interventions for partner caregivers of individuals with traumatic brain injury (TBI).
- Trial name
- NCT04192227
- Testing
- EnHAncing BehavIors through wellness TreatmentS (HABITS)
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Kessler Foundation
Traumatic Brain Injury
Promoting Neuroplastic Changes of Patients With TBI
This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage…
- Trial name
- NCT06465290
- Testing
- Motor relearning training with wearable ankle robot, Passive stretching with wearable ankle robot, Gamed-based active movement training with wearable ankle robot
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Brain Concussion
Active Injury Management (AIM) After Pediatric Concussion
The proposed interventions of this study will determine the ideal discharge recommendations related to activity
- Trial name
- AIM (NCT03869970)
- Testing
- REST, ACTIVITY, mHEALTH
- Where
- 2 sites in United States
- Volunteers
- 237 people
- Sponsor
- Medical College of Wisconsin
Traumatic Brain Injury
Safety of Dexmedetomidine in Severe Traumatic Brain Injury
The aim of this study is to assess the safety and feasibility of dexmedetomidine as an adjunct to conventional sedative therapy compared to conventional sedative therapy alone in patients with severe traumatic brain injury.
- Trial name
- NCT01007773
- Testing
- Precedex, Propofol, Fentanyl
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Brain Injuries, Traumatic, Brain Injury Traumatic Mild
Usability and Tolerability of Novel Protection Device Against Potential Brain Injury During Competitive Sport
The purpose of the study is to assess the usability and tolerability of this jugular vein compression device in a population of helmeted and non-helmeted competitive high school, collegiate and professional athletes in the sports…
- Trial name
- NCT03318822
- Testing
- Q-Collar
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Emory University
Traumatic Brain Injuries
Standard Craniectomy Against Laparotomy for the Treatment of Traumatic Rise in Intracranial Pressure and the Effect on Long-term Outcome
Intractable high intracranial pressures (ICP) are associated with poor functional outcomes and mortality, so the SCALPEL trials aims to evaluate the effect of decompressive craniectomy against decompressive laparotomy to lower…
- Trial name
- SCALPEL (NCT05115929)
- Testing
- Decompressive Laparotomy, Decompressive Craniectomy
- Where
- 4 sites in France, Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Traumatic Brain Injury, Concussion, Brain
Understanding Concussion/Mild Traumatic Brain Injury
Using the Blink Reflexometer, athletes are scanned if they are potentially thought to have a concussion during a game or practice.
- Trial name
- NCT03381638
- Testing
- Blink Reflexometer
- Where
- 5 sites in United States
- Volunteers
- 477 people, healthy volunteers welcome
- Sponsor
- Blinktbi, Inc.
Traumatic Brain Injury
Advanced MRI in Blast-related TBI
Thousands of soldiers, marines, and other military personnel have had injuries to the brain due the wars in Iraq and Afghanistan.
- Trial name
- NCT00785304
- Where
- 2 sites in United States, Germany
- Volunteers
- 100 people
- Sponsor
- Washington University School of Medicine
Brain Injury, Craniocerebral Trauma
PariS -TBI Study: Paris Severe Traumatic Brain Injury Study - 8 Years
The objective of the protocol is to pursue the long-term follow-up of a large cohort of severe traumatic brain injury patients. This outcome is to be described in terms of activity, participation, quality of life…
- Conditions
- Brain Injury, Craniocerebral Trauma, Trauma, Nervous System
- Trial name
- TCS8 (NCT02050633)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mild Traumatic Brain Injury
Auditory Plasticity Training
The investigators are working on a project to help people who have had mild brain injuries hear better. Sometimes, these injuries can make it hard for people to hear clearly, especially in noisy places or when trying to tell…
- Trial name
- NCT06628505
- Testing
- Speech in Noise Training, Spatial Hearing Training Group, Spatial Hearing Control Group
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Concussion, Mild, Neurocognitive Dysfunction
Biomarker Levels as A Predictor of Concussion Severity OUTcomes (BlacOut)
The overall research aim of this pilot study is to determine if the structural brain protein calpain-cleaved αII-spectrin N-terminal fragment (SNTF) can be used as a blood biomarker to accurately identify patients who will have…
- Trial name
- BlacOut (NCT02992327)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Dementia, Mixed, Dementia Mild
An Innovative Supportive Care Model for Dementia and Traumatic Brain Injury
There are an increasing number of people in the U.S. with Alzheimer's disease and other dementias. Traumatic brain injuries (TBIs) are also common among both civilians and military personnel, and TBIs increase a person's risk for…
- Conditions
- Dementia, Mixed, Dementia Mild, Dementia Moderate, Traumatic Brain Injury
- Trial name
- NCT04495686
- Testing
- Telehealth-delivered Care Coordination Program
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- University of Virginia
Traumatic Brain Injury, Walking Impairment
Treadmill Training at Constant or Different Speeds for People With Traumatic Brain Injury
Background: Many people who have had a traumatic brain injury have difficulty walking. Training on a treadmill is often used to help people with walking difficulties.
- Conditions
- Traumatic Brain Injury, Walking Impairment, Gait Training
- Trial name
- NCT01419522
- Testing
- Gait Training Method
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Vestibular Hypofunction
Improving Psychological and Vestibular Health: MINDGAPS
The purpose of this study is twofold: 1) Develop norms for measures of inner ear function and psychological health, and 2) Examine the feasibility of using the MINDGAPS system (a remote monitoring system) to track progress during…
- Trial name
- MINDGAPS (NCT05986279)
- Testing
- Rehab
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Montana
Anterior Cruciate Ligament Injuries, Concussion, Brain
Making Football Safer for Women: Implementing an Injury Prevention Program
The aim of this study is to determine how we can best support coaches to implement an injury prevention (IP) program (Prep-to-Play) in female community Australian Football.
- Conditions
- Anterior Cruciate Ligament Injuries, Concussion, Brain, Musculoskeletal Injury
- Trial name
- Prep-to-Play (NCT04856241)
- Testing
- Coaching, Peer support, Educational materials
- Where
- Australia
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- La Trobe University
Traumatic Brain Injury
Neurocognitive Driving Rehabilitation in Virtual Environments (NeuroDRIVE) as an Adjunctive Intervention for Traumatic Brain Injury
Background: People with traumatic brain injury (TBI) can have problems with thinking and everyday activities. They may have a higher risk for car accidents. NeuroDRIVE uses a virtual reality driving simulator.
- Trial name
- NCT02411227
- Testing
- VR Driving
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
TBI (Traumatic Brain Injury), Stroke
Cognitive Profile of Patients at the Sagol Center for Hyperbaric Medicine and Research
In the investigator's institute there is ongoing treatment of different patients with cognitive deficits using Hyperbaric oxygen therapy (HBOT).
- Conditions
- TBI (Traumatic Brain Injury), Stroke, Fibromyalgia, Aging
- Trial name
- NCT04287283
- Testing
- Hyperbaric Oxygen
- Where
- Israel
- Volunteers
- 2,500 people
- Sponsor
- Assaf-Harofeh Medical Center
Traumatic Brain Injury, Severe Traumatic Brain Injury
Aquatic Sequential Preparatory Approach and Severe Traumatic Brain Injury
Traumatic brain injury (TBI) is an acquired insult to the brain from an external mechanical force. It is considered a major cause of mortality and of long-term disabilities in young adults, especially considering high-income…
- Trial name
- NCT04383405
- Testing
- Aquatic Training, Conventional Training
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Brain Concussion, Brain Trauma
tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study
The proposed study will evaluate a new approach to cognitive rehabilitation of mild traumatic brain injury (mTBI) using a brain stimulation technique called transcranial direct current stimulation (tDCS).
- Conditions
- Brain Concussion, Brain Trauma, Attention Concentration Difficulty, Brain Injuries
- Trial name
- NCT04925453
- Testing
- active tDCS and cognitive training intervention
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- United States Naval Medical Center, San Diego
Traumatic Brain Injury
The Paracetamol AfteR Traumatic Brain InjurY Study
This primary aim is to investigate the effect of paracetamol in reducing body temperature in patients who have sustained traumatic brain injury.
- Trial name
- PARITY (NCT01231139)
- Testing
- Paracetamol, 0.9% Sodium Chloride Schedule:
- Where
- 2 sites in Australia
- Volunteers
- 41 people
- Sponsor
- Dr. M.K. Saxena
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