Clinical trials: Traumatic Brain Injury With Prolonged Loss of Consciousness
Traumatic Brain Injury With Prolonged Loss of Consciousness
A Trial to Determine the Feasibility and Effectiveness of Early Multisensory Stimulation Intervention in Patients in the Trauma-Neurosurgical Intensive Care Unit (TNICU) Following Severe Acquired Brain Injury
St. Michael's Hospital (SMH) provides service to individuals with some of the most severe brain injuries and intensive care needs in Canada.
- Trial name
- NCT02589223
- Testing
- Multisensory Stimulation, Control
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Unity Health Toronto
Disorder of Consciousness, Vegetative State
The Use of LIFUP in Chronic Disorders of Consciousness
When patients survive a severe brain injury but fail to fully recover, they often enter a Disorder of Consciousness (DoC) --that is, a set of related conditions of decreased awareness and arousal including the Vegetative State…
- Conditions
- Disorder of Consciousness, Vegetative State, Minimally Conscious State, Minimally Conscious State Plus
- Trial name
- NCT04921683
- Testing
- BX Pulsar 1002 (LIFUP) Low intensity Focused Ultrasound Pulsation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Casa Colina Hospital and Centers for Healthcare
Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury
Promoting Recovery After Brain Injury Using Focused Ultrasound
The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover.
- Trial name
- ReBOUND (NCT07277309)
- Testing
- Low-intensity focused ultrasound
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Massachusetts General Hospital
Traumatic Brain Injury, Concussion, Intermediate
Intervention to Change Affect Recognition and Empathy
Determine the feasibility, practicality, and early efficacy of a TeleRehab program (ICARE) to improve outcomes for persons with traumatic brain injury (TBI) in recognizing and responding to others' emotions alongside their care…
- Conditions
- Traumatic Brain Injury, Concussion, Intermediate, Concussion, Severe, Concussion With LOC 31 to 59 Minutes
- Trial name
- ICARE (NCT05636020)
- Testing
- ICARE Treatment
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Indiana University
Consciousness Disorders, Disorders of Consciousness Due to Severe Brain Injury
Ultrasound Stimulation for Patients in a Disorder of Consciousness
The overall aim of this study is to develop an intervention that can help recovery in patients surviving severe brain injury but failing to fully recover.
- Trial name
- tFUS (NCT06939348)
- Testing
- The Brainsonix BX Pulsar 1002 was designed to deliver low-intensity focused ultrasound pulsations (LIFUP) to the human brain.
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of California, Los Angeles
Traumatic Brain Injury With Prolonged Loss of Consciousness
Low-Intensity Focused Ultrasound on Individuals With Disorder of Consciousness of Traumatic Brain Injury
Low-intensity focused ultrasound can be effective in severe TBI patients with disorder of consciousness. This study is a prospective single arm, open-label and explorative clinical trial to evaluate the therapeutic effect of…
- Trial name
- NCT04306601
- Testing
- Low-Intensity Focused Ultrasound
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Seoul National University Hospital
Traumatic Brain Injury With Prolonged Loss of Consciousness, Stroke
Evaluation of Consciousness by Brain-computer Interface in Severely Brain Damaged Patients
The objective of this study is to show that the measurement of auditory and vibro-tactile evoked potentials, or the recording of the EEG signal during a motor imaging task, can be used in routine clinical situations to explore…
- Conditions
- Traumatic Brain Injury With Prolonged Loss of Consciousness, Stroke, Brain Hypoxia
- Trial name
- AWAKE (NCT03998930)
- Testing
- Clinical evaluation of consciousness by the Coma Recovery Scale Revised (CRS-R)
- Where
- 4 sites in France
- Volunteers
- 9 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes