Clinical trials: Traumatic Events
Post-traumatic Stress Disorder (PTSD), Intrusive Memories of Traumatic Event(s)
Tetris Intervention Following Subliminal Reactivation for Intrusive Memories
Intrusive memories of traumatic events are a core feature of Post-Traumatic Stress Disorder (PTSD) and can cause substantial distress and functional impairment.
- Trial name
- NCT07495917
- Testing
- Subliminal Reactivation Followed by Visuospatial Interference, Computer-based Visuospatial Task (Tetris)
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Shaanxi Normal University
Arthritis, Rheumatoid, Stress Disorder
Impact of Life Events and Psychological Stress in Rheumatoid Arthritis Set-up : Case-control Study Within a Multifactorial and Integrative Psychological Model
Rheumatoid Arthritis (RA) is an inflammatory rheumatic disease that can lead to structural damage and handicap. The RA physiopathology is multifactorial, including genetic and environmental risk factors.
- Trial name
- Stress-PR (NCT03550833)
- Testing
- Questionnaire, blood sample
- Where
- 5 sites in France
- Volunteers
- 152 people
- Sponsor
- University Hospital, Bordeaux
Intergenerational Trauma
Child Cognitive-Affective Resilience Following 13-11 Event : A Pluridisciplinary Study of Intergenerational Transmission of a Traumatic Event
CARE 13-11 study explores the transmission of trauma within families. Exposure to a traumatic event can have an impact on those directly exposed, but also on their family.
- Trial name
- CARE 13-11 (NCT07203443)
- Testing
- MRI, Psychological assessment, Cognitive assessment
- Where
- France
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Traumatic Brain Injury
A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury
The study is intended to cover two purposes: first, to develop a blood-based biomarker test for aiding the diagnosis of traumatic brain injury (TBI) in adult participants and for prognosis of outcome of TBI (CLIN12.1); and…
- Trial name
- NCT07455136
- Testing
- Blood sample collection
- Where
- 14 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Hoffmann-La Roche
Posttraumatic Stress Disorder, Myocardial Infarction
EMDR Treatment in PTSD Following Cardiac Events
Cardiac events can often result in debilitating and persistent psychological symptoms. A key question involves whether optimal treatment of cardiac-induced posttraumatic stress disorder (PTSD) reduces PTSD symptoms and thereby…
- Conditions
- Posttraumatic Stress Disorder, Myocardial Infarction, Eye Movement Desensitization and Reprocessing
- Trial name
- EMDR_PTSD_MI (NCT04672551)
- Testing
- EMDR Treatment
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Posttraumatic Stress Disorder
Imaginal Exposure & D-Cycloserine (DCS) for Posttraumatic Stress Disorder (PTSD)
This study proposes to evaluate the effects of D-cycloserine (DCS) combined with cognitive-behavioral treatment with exposure therapy in a sample of patients who developed posttraumatic stress disorder (PTSD) as a consequence of…
- Trial name
- NCT00875342
- Testing
- DCS
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Weill Medical College of Cornell University
Spinal Cord Injury, Cervical Spondylosis With Myelopathy
High-Resolution Diffusion Tensor Imaging (DTI) of the Cervical Spinal Cord in the Setting of Spinal Cord Injury (SCI)
The investigators propose a prospective study, designed to analyze the efficacy of High-Resolution Diffusion Tensor Imaging for accurately sensing white matter tracts in subjects with spinal cord injury.
- Conditions
- Spinal Cord Injury, Cervical Spondylosis With Myelopathy, Degenerative Disorder
- Trial name
- NCT01407705
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Utah
PTSD
Cognitive-behavioral Therapy for Treatment of Post-traumatic Stress Disorder and Related Problems
The purpose of this study is to evaluate the efficacy of a form of cognitive behavioral therapy (CBT) in a population of individuals with PTSD and common related problems (depression, anxiety or sleep disorders, pain…
- Trial name
- CBT-PTSD-RP (NCT03019497)
- Testing
- Specific Modules, Cognitive behavioral therapy
- Where
- Canada
- Volunteers
- 92 people
- Sponsor
- Université de Montréal
IBS - Irritable Bowel Syndrome, Constipation
Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders
The purpose of this study is study bowel symptoms, quality of life, and personal factors that may affect your health. In Aim 1 of this study participants will be invited to complete 6 survey-based questionnaires online.
- Trial name
- PTSD (NCT04060121)
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Indiana University
Posttraumatic Stress Disorder, Acute Post-Traumatic Stress Disorder
Prevention of Mental Health Problems in People Exposed to a Recent Highly Stressful Event.
This project evaluates the effectiveness of three intervention models for the prevention of mental health problems in people who have suffered a recent highly stressful event, through an experimental design, with a control group…
- Conditions
- Posttraumatic Stress Disorder, Acute Post-Traumatic Stress Disorder, Depressive Symptoms
- Trial name
- NCT04314115
- Testing
- Mindfulness, Systemic therapy, Cognitive behavioral therapy and positive psychology
- Where
- Chile
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas, Chile
Post Traumatic Stress Disorder
People Bereaved by Violent Death : Negative Event Biases and Temporal Perception
A violent death is defined by its brutality, unexpectedness and is secondary to an external cause (suicide, homicide, accident).
- Trial name
- PrEVENT (NCT05874362)
- Testing
- Diagnosis of depressive episode or post traumatic stress disorder, No diagnosis of depressive episode or post traumatic stress disorder
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Hôpital le Vinatier
Combat Disorders
Prospective Study of Veteran Health in Previously Deployed Soldiers
Background: Previous deployments like that to the Persian Gulf in 1991 produced veterans with post-deployment symptom-based health problems with no medical explanation.
- Trial name
- NCT00285246
- Where
- 2 sites in United States
- Volunteers
- 838 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Hemorrhage, Thrombosis
Adverse Drug Events in Patients on Oral Anticoagulation in the Emergency Department
Rationale: According to the latest National Survey on Care-Related Adverse Events, anticoagulants, including vitamin K antagonists (VKAs), rank first among medications responsible for serious iatrogenic accidents (37% in 2004…
- Conditions
- Hemorrhage, Thrombosis, Anticoagulant Therapy, Traumatic Hemorrhage
- Trial name
- ADEOA (NCT06692504)
- Where
- France
- Volunteers
- 2,080 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Healthy
A Trial on the Effect of Emotional Disclosure of Traumatic Life Events on Physical Health
This is a randomized, controlled trial on the effect of emotional disclosure of traumatic life events on physical health. The hypothesis is that expression of emotions could possibly improve physical health.
- Trial name
- NCT00896844
- Testing
- emotional disclosure
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham
Intervention Group, Comparison Group
Effects of Semantically Irrelevant Virtual Reality Experience on Memory and Emotion
First responders at the Federal, State and local level are those on the front lines of providing support to their communities during an emergency or a disaster.
- Conditions
- Intervention Group, Comparison Group, Control Group
- Trial name
- FIRM (NCT07393776)
- Testing
- Watching VR video, Reading text
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Child Abuse, Child Neglect
Child-Parent Psychotherapy - a Feasibility Study for Children in Foster Care
Children in foster care have an increased risk of exposure to adverse experiences during childhood and across the lifespan. In current studies of interventions children in foster care are often excluded, or they are too few to be…
- Conditions
- Child Abuse, Child Neglect, Post-Traumatic Stress Disorder in Children, Parent-Child Relations
- Trial name
- NCT04519229
- Testing
- Child-Parent Psychotherapy
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Kronoberg County Council
Suicidal Behavior, Depression
Predictors of Suicidal Behavior in Depression
This study aims at identifying predictors of suicidal behaviors in depressed subjects. Investigators will first compare demographic, clinical, and biological features of depressed recent suicide attempters (within one week) and…
- Conditions
- Suicidal Behavior, Depression, Traumatic Events, Impulsivity Aggression
- Trial name
- SECS (NCT02904005)
- Testing
- Standardized assessment on depressed patients
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Montpellier
Intrusive Memories of Traumatic Event(s), Post Traumatic Stress Disorder
Simple Cognitive Task Intervention After Trauma During COVID-19 In Hospital Staff EKUT-P RCT
This research study is designed to investigate the effects of a remotely delivered simple cognitive task (a memory cue followed by playing the computer game "Tetris" with mental rotation instructions) on intrusive memories…
- Trial name
- NCT04460014
- Testing
- Simple cognitive task intervention
- Where
- Sweden
- Volunteers
- 164 people
- Sponsor
- Karolinska Institutet
PTSD - Post Traumatic Stress Disorder, Intrusive Memories of Traumatic Event(s)
Neuromodulation of the Hippocampus to Reduce Intrusive Re-Experiencing in PTSD: A Randomized Controlled Trial
The goal of this clinical trial is to learn if non-invasive neurostimulation of memory-related brain areas works to treat intrusive memory symptoms in adults patients with posttraumatic stress disorder (PTSD).
- Trial name
- NCT06639061
- Testing
- Hippocampal stimulation using repetitive transcranial magnetic stimulation (rTMS)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel Aviv University
Fibromyalgia, Psychological Trauma
Prevalence of the Traumatic Events in Women With Fibromyalgia
Suffering a traumatic event is a potential risk factor for developing Posttraumatic Stress Disorder (PTSD) with or without comorbidities with other pathologies that can become chronic with time, including fibromyalgia.
- Conditions
- Fibromyalgia, Psychological Trauma, Pain, Anxiety
- Trial name
- NCT04476316
- Where
- Spain
- Volunteers
- 88 people
- Sponsor
- Parc de Salut Mar