Clinical trials: Traumatic Injuries
Traumatic Brain Injury
Developing Therapies for Traumatic Brain Injury
Background: A person who has a traumatic brain injury (TBI) -- also called concussion -- can have serious and long-lasting effects.
- Trial name
- NCT01420939
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Posttraumatic Stress Disorder, Traumatic Brain Injury
An Exploration of the Relationship Between Chronic Pain and Suicide Attempt Among Veterans
The purpose of this study is to explore the relationship between attempted and/or completed suicide and reported experience of chronic pain among an adult veteran population.
- Conditions
- Posttraumatic Stress Disorder, Traumatic Brain Injury, Suicide Attempt
- Trial name
- NCT01502436
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Traumatic Brain Injury, Major Depressive Disorder
MRI Markers of Feedback Timing During Learning in Individuals with TBI with and Without Clinical Depression
The goal of this proposal is to examine the influence of feedback timing on learning and brain function in individuals with moderate-to-severe traumatic brain injury (TBI), with and without depression.
- Trial name
- NCT05009511
- Testing
- Learning through feedback
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Birth, First, Pregnancy Related
The Effect of the Continuous Midwifery Care Model on Birth Outcomes
It is the right of both the mother and her baby to receive the best care and give birth in the best way possible for every pregnant woman.
- Conditions
- Birth, First, Pregnancy Related, Newborn; Fit, Trauma, Psychological
- Trial name
- NCT06020339
- Testing
- The midwife-led continuous care model (MLCC)
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Hazardous Drinking, Posttraumatic Stress Disorder
PFI Hazardous Drinkers With Subclinical PTSD
The objective of the present study is to assist on a randomized controlled trial (RCT), aimed at developing and testing the efficacy of a novel computer based PFI among hazardous drinkers with at least subclinical posttraumatic…
- Trial name
- NCT04836442
- Testing
- Alcohol-PTSD-PFI (AP-PFI), Active Comparison Condition (C-PFI)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Houston
Sexual Abuse of Child (If Focus of Attention is on Victim)
A 1-year Program to Treat Children Who Have Been Victims of Child Sexual Abuse
Our goal in this study is examine if a program designed to decrease the severity of Post-Traumatic Stress Disorder symptoms in sexually abused children between the ages of 8-12 was effective.
- Trial name
- NCT02181751
- Testing
- Trauma Focused Cognitive Behavioural Therapy Group
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Little Warriors
Traumatic Brain Injury
Problem Solving for Caregivers of Persons With Brain Injury
This study was designed to evaluate a behavioral intervention program to improve medication adherence in adults with hypertension. The study was withdrawn prior to enrollment.
- Trial name
- NCT00164645
- Testing
- Problem Solving Therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Depression, Anxiety
Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment
Childhood trauma is remarkably prevalent, and it has long lasting impact on mental health and neural development. This trial aims to see whether the 8-week mindfulness based intervention can reduce stress related psychological…
- Conditions
- Depression, Anxiety, PTSD, Trauma, Psychological
- Trial name
- NCT02447744
- Testing
- Mindfulness based intervention
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stress Disorders, Post-traumatic, Substance Use Disorders
Peer Supported Web-based CBT for OEF/OIF Veterans With PTSD and Substance Misuse
Veterans who served in Iraq and Afghanistan have high rates of co-morbid PTSD symptoms and hazardous substance use (HSU). Evidence-based treatments for these problems are available in VA specialty clinics, but multiple barriers…
- Trial name
- NCT02611843
- Testing
- Peer-Supported Web CBT, Self-Managed Web CBT
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
Ambulances, Traumatic Brain Injury
Differences in Mortality and Morbidity in Patients Suffering a Time-critical Condition Between GEMS and HEMS
Introduction: Patients suffering a time-critical medical condition require rapid prehospital assessment and treatment and most often quick transportation to definitive care. This can be decisive for patient outcome.
- Conditions
- Ambulances, Traumatic Brain Injury, Acute Myocardial Infarction
- Trial name
- NCT03940443
- Where
- Sweden
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Brain Injuries
CDP-Choline and Working Memory After TBI: A Neuroimaging Study
The purpose of this study is to determine whether an investigational drug, called "CDP-Choline", improves memory in people with traumatic brain injury (TBI).
- Trial name
- NCT00727246
- Testing
- CDP-Choline
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Patricia M. Arenth
Traumatic Brain Injury, Gait Disorders, Neurologic
Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients
The project will consist of subjects who have suffered Traumatic Brain Injury (TBI) and who are able to ambulate on treadmill with or without a harness system.
- Trial name
- NCT05622786
- Testing
- HIGT - physical rehab, Low intensity physical therapy
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Traumatic Brain Injury
Impact of Traumatic Brain Injury on Cognitive Function, Balance and Functional Independence in Children
The purpose of the study is to determine the impact of different levels of traumatic brain injury on cognitive function, functional independence and balance on children and relation of cognitive dysfunction, balance disturbance…
- Trial name
- Impact TBI (NCT07612410)
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Traumatic Brain Injury
Evaluation of Consciousness Impairment in Severe TBI and Full-cycle Neuroregulation Based on Multimodal Imaging
The goal of this observational study is to learn about in Evaluation of consciousness impairment in severe TBI and full-cycle neuroregulation based on multimodal imaging.
- Trial name
- NCT06469827
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Ischemic Stroke, Hemorrhagic Stroke
Stroke and Traumatic Acute Brain Injury Line Indicator System for Emergent Recognition (STABILISER-I)
In the search for a novel marker of stroke that could be rapidly assessed in blood, the investigators developed a point-of-care (POC) lateral flow device (LFD) that rapidly (< 15 min) detects levels of a biomarker that is…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, Traumatic Brain Injury
- Trial name
- STABILISER-I (NCT02514902)
- Testing
- Lateral Flow Device
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Justin Fraser
TBI (Traumatic Brain Injury), PTSD
Translational Research Center for TBI and Stress Disorders: Virtual Assessment of Deployment Trauma and Rehabilitation
For this clinical demonstration study, Veterans will be assessed with a battery of questionnaires/surveys and a 1:1 clinical interview with a V-TRACTS psychologist to target domains of head injury, psychological trauma…
- Trial name
- V-TRACTS (NCT04723745)
- Testing
- V-TRACTS Assessment/Feedback, OPTIONAL Brief Assessment of Thinking, OPTIONAL STEP-Home-Brief
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
Moral Distress, Moral Injury
Coping and Adaptation for Recovery From Moral Injury: A Group Intervention for Clinical Psychology Residents
Moral distress may arise when health care professionals are unable to act in accordance with their professional values or believe that they have participated in, witnessed, or been unable to prevent situations that conflict with…
- Trial name
- CARE-MI (NCT07887581)
- Testing
- CARE-MI Group Intervention
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
Mindfulness for Cognition in Early-stage Alzheimer's Disease
The goal of this clinical trial is to learn if mindfulness meditation can improve outcomes in older adults with and without cognitive impairment. The main questions it aims to answer are: 1.
- Conditions
- Mild Cognitive Impairment (MCI), Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease, TBI (Traumatic Brain Injury), Aging
- Trial name
- NCT06792877
- Testing
- Mindfulness Intervention, Waitlist then mindfulness
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- VA Boston Healthcare System
Brain Concussion, Posttraumatic Stress Disorder
Brain Injury Outcomes (BIO) Study
Many active duty military, national guard, and reserves personnel who served in the recent conflicts in Afghanistan and Iraq were exposed to blasts and other mechanisms of traumatic brain injury (TBI).1,2 Although physical trauma…
- Conditions
- Brain Concussion, Posttraumatic Stress Disorder, Dementia
- Trial name
- BIO (NCT00724607)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depressive Symptoms, Trauma, Psychological
Sharing HaRT in New Expanses
The goal of this parallel cluster randomized control (CRT) trial is to evaluate a group-based mind-body intervention (Move with HaRT) in survivors of human trafficking. The main study aims are: 1.
- Conditions
- Depressive Symptoms, Trauma, Psychological, Anxiety Generalized
- Trial name
- SHiNE (NCT06237439)
- Testing
- Move with HaRT
- Where
- Uganda
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
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