Clinical trials: Traumatic Injuries
Acute Stress Disorder
Micro-Dose, Macro-Impact: Leveraging Psychedelics in Frontline Healthcare Workers During the COVID-19 Pandemic
A retrospective chart review of an open-label trial of low-dose ketamine administered to front-line Healthcare workers who were identified as experiencing acute stress disorder due to the COVID-19 Pandemic.
- Trial name
- NCT04769297
- Testing
- Sublingual Micro-Dose Ketamine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Limbic Medical
Phantom Limb
Study to Identify the Genetic Variations Associated With Phantom Limb Pain
The purpose of this study is to determine if there is a genetic component to phantom limb pain. DNA will be analyzed for single nucleotide polymorphisms (SNPs) between the control and phantom limb pain group.
- Trial name
- NCT01462448
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Chronic Subdural Hematoma
Mgt of Chronic Subdural Hematoma Using Dexamethasone
Chronic subdural hematoma (cSDH) is a collection of blood and its breakdown products in the subdural compartment. It is a condition frequently seen in any neurosurgical practice.
- Trial name
- NCT02938468
- Testing
- Dexamethasone, Any surgical intervention aim at treating chronic subdural hematoma
- Where
- Canada
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Vestibular Disorder
Vestibular Treatment in Adolescents Following Sport Related Concussion
Each year, nearly 2 million children and adolescents have a sport-related concussion (SRC) in the U.S., but 57% of them do not receive appropriate clinical care following their injury.
- Trial name
- NCT03555370
- Testing
- Vestibular Exercise Intervention, Standard of Care
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Posttraumatic Stress Disorder (PTSD), Avoidant Personality Disorder
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and CPD
The goal of PROSPER-C is to study effectiveness of ImRs compared to integrated SFT-ImRs in treatment-seeking, adult patients with comorbid PTSD and Cluster C Personality Disorder (CPD).
- Conditions
- Posttraumatic Stress Disorder (PTSD), Avoidant Personality Disorder, Dependent Personality Disorder, Obsessive Compulsive Personality Disorder
- Trial name
- PROSPER-C (NCT03833531)
- Testing
- ImRS, SFT
- Where
- Netherlands
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Arkin
Healthy, CVA
Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019.
DELPhI software developed for the analysis of EEG recordings in response to magnetic stimulation in relation to clinical data.
- Conditions
- Healthy, CVA, Hemorrhage, TBI (Traumatic Brain Injury)
- Trial name
- NCT04095377
- Testing
- No intervention, this is a retrospective study.
- Where
- Israel
- Volunteers
- 875 people, healthy volunteers welcome
- Sponsor
- QuantalX Neuroscience
PTSD, Critical Illness
The Experiences of Children and Caregivers Given PICU Storybooks
1. To assess the acceptability and feasibility of a study design aimed at evaluating the efficacy of a newly developed intervention for children and their caregivers following discharge from PICU 2.
- Conditions
- PTSD, Critical Illness, Depression, Anxiety
- Trial name
- NCT04041401
- Testing
- PICU storybook
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Health Behavior
Wearable Emotion Prosthetics for Post Traumatic Stress Disorder
Involuntary stress reactions including hyper-reactivity and dissociation are key diagnostic features of many psychiatric disorders, are difficult to treat, and predict poor outcomes in conventional and neurobehavioral…
- Trial name
- EP-PTSD (NCT03529981)
- Testing
- Tuned Vibroacoustic Stimulation (TVS), no active intervention
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Concussion Mild, Concussion, Brain
Sport-Related Concussion Recovery in Athletes
The goal of this study is to enhance the accuracy and sensitivity of concussion evaluation by integrating traditional assessment tools with emerging neuroimaging technologies, such as Functional Near-Infrared Spectroscopy…
- Trial name
- NCT06852300
- Testing
- Concussion Assessment Battery
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Central Arkansas
Inflammation, Mental Health Wellness 1
Health Effects of Traditional Indigenous Chokeberry
American Indian populations continue to suffer disproportionately from health problems including such nutrition-related chronic diseases as diabetes and heart disease.
- Conditions
- Inflammation, Mental Health Wellness 1, Oxidative Stress
- Trial name
- NCT05410327
- Testing
- Chokeberry (Aronia melanocarpa) juice
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of North Dakota
Epilepsy, Functional Neurological Disorder
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
The goal of this study is to investigate how a one-time exercise session influences different parameters of brain function in people with neurological diseases compared to healthy volunteers.
- Conditions
- Epilepsy, Functional Neurological Disorder, Mild Cognitive Impairment, Dementia
- Trial name
- EXPLAIN (NCT07883720)
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Brain Injuries, Traumatic
mTBI Identification and Monitoring Through Retinal Scanning
Rebion has developed a device, the Rebion trauma tool (referred to as the head and intraocular trauma tool, or "HITT"), that detects ocular fixation and alignment using a binocular retinal scan.
- Trial name
- NCT06142435
- Testing
- Head and Intraocular Trauma Tool
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rebiscan, Inc.
Health Adults, Patients With Traumatic Hand Injury
Ultrasonography-guided Real-time Modular Systems for Hand Therapy
This study aimed to develop an ultrasonography-guided real-time modular system and try to apply it to clinical hand therapy using. This study was divided into two parts. The first part is an observational study design.
- Trial name
- NCT06189235
- Testing
- Biofeedback training
- Where
- Taiwan
- Volunteers
- 149 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Intervention Effectiveness, Practice-based Evidence
Strengthening Family Coping Resources Open Trials
Strengthening Families Coping Resources (SFCR) Open Trials completes the second stage of the National Institute on Drug Abuse's intervention development model by testing a new family, skills-based intervention involving pre-post…
- Conditions
- Intervention Effectiveness, Practice-based Evidence, Posttraumatic Stress Disorder
- Trial name
- SFCR (NCT01754610)
- Testing
- Strengthening Family Coping Resources (SFCR)
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Concussion, Brain
Diffusion Tensor Brain MRI in the Detection of Structural Abnormality of the White Substance in Concussion
Concussions in sports are a major public health problem because of their frequency, and are often underdiagnosed because of an unspecific clinical picture or sometimes masked by the concussion itself.
- Trial name
- COMMOTION (NCT06144359)
- Testing
- specific MRI Acquisition (Diffusion Tensor Imaging) at 3T
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Anxiety, Stress Disorder, Posttraumatic
BLOOM: Boldly Living outdOOrs for Mental Health
In 2019, the Office of the California Surgeon General launched the ACEs Aware Initiative in collaboration with the California Department of Health Care Services.
- Conditions
- Anxiety, Stress Disorder, Posttraumatic, Loneliness, Adverse Childhood Experiences
- Trial name
- BLOOM (NCT05973123)
- Testing
- Group Nature Outings, Family Outings
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cancer, Healthcare Professionnals
Assessment of Cancer-related Post-traumatic Stress in Patients and Caregivers in the Year Following Diagnosis, and Identification of Their Expectations of Personalized Support - CANDYSTRESS
The impact of cancer on the lives of patients and their caregivers is undeniable. In addition to the potentially traumatic aspects (i.e., creating a very violent emotional shock) linked to the announcement of the disease and the…
- Conditions
- Cancer, Healthcare Professionnals, Caregiver Distress, Caregiver
- Trial name
- CANDYSTRESS (NCT06944262)
- Where
- 2 sites in France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Lille University
Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases
NightWare and Cardiovascular Health in Veterans With PTSD
The purpose of this study is to learn more about the effectiveness of a prescription wrist-wearable device called NightWare (NW) on improving sleep in Veterans with nightmares related to posttraumatic stress disorder (PTSD).
- Conditions
- Post-traumatic Stress Disorder (PTSD), Cardiovascular Diseases, Autonomic Dysfunction, Vascular Stiffness
- Trial name
- NCT06419959
- Testing
- NightWare
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury
Developing and Validating Blood and Imaging BIOmarkers of AXonal Injury Following Traumatic Brain Injury
Observational longitudinal study assessing outcomes following moderate-severe traumatic brain injury (TBI).
- Trial name
- BIO-AX-TBI (NCT03534154)
- Testing
- MRI, Blood Sampling, Microdialysis
- Where
- 5 sites in Italy, Slovenia and 2 more
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Traumatic Brain Injury
Exercise and Rehabilitation After Traumatic Brain Injury
The purpose of this study is to examine the effects of exercise on recovery after traumatic brain injury. Investigators will determine if exercise enhances rehabilitation by increasing substances (proteins) that can facilitate…
- Trial name
- NCT03407924
- Testing
- Aerobic Exercise (AER), Rehabilitation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Centre for Neuro Skills
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