Clinical trials: Traumatic Injuries
Low-level Blast Exposure
Blast Overpressure Longitudinal Study
The goal of this observational study is to learn about the impact of low-level blast exposure in U.S. Special Operations Forces personnel.
- Trial name
- BLES (NCT07606651)
- Where
- 3 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Posttraumatic Stress Disorder
Investigating Cardiac Health of Adults With Trauma
This project examines the impact of a healthy lifestyle intervention, specifically designed for adults with posttraumatic stress and identified cardiovascular risks.
- Trial name
- I - CHAT (NCT05700201)
- Testing
- Lifestyle / Healthy Behavior Intervention, standard care
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
PTSD - Post Traumatic Stress Disorder
Neural Basis of the Effect of EMDR Therapy
This study aimed to investigate the effects of a single session of Butterfly Tapping (BT), a self-administered form of alternating bilateral stimulation, on emotional reactivity and its neurophysiological correlates.
- Trial name
- EMDR-NEURO (NCT07550556)
- Testing
- Butterfly Tapping (BT), No intervention control
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Rome Foro Italico
Traumatic Brain Injury
Repeatability Assessment of Neurovisual Tasks for the Construction of a New Concussion Monitoring Tool (SPORTICARE)
Traumatic brain injury (TBI) is a condition that occurs when a mechanical blow to the head causes damage to the brain. The diagnosis of this pathology requires the evaluation of several dimensions, including clinical symptoms…
- Trial name
- SPORTiCARE (NCT05992194)
- Testing
- multimodal oculomotor measurements
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Posttraumatic Stress Disorder (PTSD)
Cognitive Processing Therapy for Syrian Patients With PTSD
Background: Studies among Syrian refugees showed high prevalence rates of PTSD. The objective of the present study was to investigate the effectiveness of Cognitive Processing Therapy (CPT) in treating patients with posttraumatic…
- Trial name
- CPT4Syrians (NCT05031728)
- Testing
- Cognitive Processing Therapy (CPT)
- Where
- Egypt
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Stress Disorders
Strength and Awareness in Action
The aims of this research study are to 1) assess the acceptability and feasibility of conducting a yoga-based intervention for Veterans receiving care at a Veterans Affairs Medical Center, and 2) obtain preliminary data regarding…
- Trial name
- NCT01717547
- Testing
- Yoga-based treatment
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- VA Eastern Colorado Health Care System
Traumatic Brain Injury, Concussion
Enhancing Cognitive and Neurobehavioral Functions After Repetitive Traumatic Brain Injuries (rTBI) in Retired NFL Players and Military Veterans.
The purpose of this study is to compare different combinations of cognitive training in retired professional football players and military veterans with a history of repeated concussions and persistent symptoms of impaired…
- Conditions
- Traumatic Brain Injury, Concussion, Mild Cognitive Disorder
- Trial name
- NCT02699476
- Testing
- Psycho-Social Therapy, Cognitive Behavioral Computer Training, Interactive Trainer-Subject Sessions
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brain & Body Health Foundation
Concussion, Mild, Autonomic Nervous System
Acute Nerve Stimulation For Enhancing Human and Cognitive Performance
The goal of this clinical trial is to test a wearable device's effect on performance in tactical populations with a history of concussion.
- Conditions
- Concussion, Mild, Autonomic Nervous System, Cognitive
- Trial name
- NCT05675956
- Testing
- Experimental group with 100% intensity setting on Apollo Neuro device, Active Comparator group with 10% intensity setting on the Apollo Neuro device
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Traumatic Skin Loss, 2nd and 3rd Degree Burn, Post Tumour Excision - Raw Areas Undergoes Split- Thickness Skin Grafts
Evaluation of the Use of Minced Skin Grafts for Promoting Donor Site Wound Healing After Split-Thickness Skin Grafting
Split-thickness skin grafting (STSG) is one of the most commonly performed procedures to achieve wound closure. Most studies are concerned on improving the appearance of scars and shortening the healing time of the recipient…
- Trial name
- NCT06488612
- Testing
- Minced skin grafts for donor site
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sohag University
Fear, GAD
Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans
Anxiety disorders such as post-traumatic stress disorder (PTSD) and generalized anxiety disorder (GAD) affect a large number of individuals with a significant portion of patients failing to improve with current treatments.
- Conditions
- Fear, GAD, Emotional Memory, PTSD
- Trial name
- NCT05120635
- Testing
- Deep Brain Stimulation, Virtual and augmented reality tasks
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duke University
Agitated; State, Acute Reaction to Stress, Agitation,Psychomotor
Mindful Melody: Feasibility of Implementing Music Listening on an Inpatient Psychiatric Unit and Its Relation to the Use of As Needed Medications for Acute Agitation
In this quality improvement project, our objectives were to assess the feasibility and effectiveness of using music as an adjunct to or replacement of pharmacological interventions for patient agitation on an inpatient…
- Trial name
- NCT04514432
- Testing
- Music
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Post Traumatic Stress Disorder
Does a Follow-up Appointment Help Parents of Children on PICU?
The aim of our study is to determine the feasibility of carrying out a randomized controlled trial (RCT) to investigate whether screening parents of children admitted to pediatric intensive care unit (PICU) so as to target…
- Trial name
- PICUfu (NCT01628263)
- Testing
- Follow up Clinic for High risk participants
- Where
- United Kingdom
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Appetitive Aggression, Post-traumatic Stress Disorder
Intervention to Support the Reintegration of Former Combatants and Soldiers
The project aims to investigate if trauma-related disorders and appetitive aggression can be reduced in former ex-combatants in DR Congo when a specific intervention (Narrative Exposure Therapy for Forensic Offender…
- Trial name
- NCT01624987
- Testing
- NET for Forensic Offender Rehabilitation (FORNET): a variant of Narrative Exposure Therapy, Control group
- Where
- Republic of the Congo
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Konstanz
PTSD, Ketosis
Ketone Supplementation in Individuals With PTSD
The purpose of this study is to determine if a 6-week period of ketone salt supplementation affects physiological, emotional, cognitive, and/or behavioral health markers in individuals with PTSD.
- Trial name
- NCT04083352
- Testing
- Pruvit Ketomax Ketone Salt
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Augusta University
Posttraumatic Stress Disorder, Sexual Assault
RCT for Innovating Stress-related eHealth
The Randomized Control Trial for Innovating Stress-related eHealth (RISE) Study tests the hypotheses that a highly promising digital therapeutic (RISE Guide) targeting anxiety sensitivity (AS) will be acceptable to women sexual…
- Conditions
- Posttraumatic Stress Disorder, Sexual Assault, Pain
- Trial name
- RISE (NCT05305235)
- Testing
- RISE Guide, Relaxation Control
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anxiety Disorders, Post Traumatic Stress Syndrome
Auricular Acupuncture as an add-on Treatment for Symptoms of Anxiety
Mental illness is very common in todays' society, and it is the most common cause for sick leave in Sweden. Affective diseases, such as different states of anxiety and depression, are the two most common conditions of mental…
- Trial name
- NCT04654884
- Testing
- Auricular acupuncture (AA)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Posttraumatic Stress Disorder, Depression
Randomized Controlled Trial of the Effectiveness of Group Treatment With War-Exposed Bosnian Adolescents
Context: This is the first multi-site randomized controlled study of the effectiveness of a group treatment for war-exposed adolescents delivered in-country within a public school system.
- Conditions
- Posttraumatic Stress Disorder, Depression, Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT00480480
- Testing
- Trauma and Grief Component Therapy for Adolescents (Group Version)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Brain Injuries, Brain Injuries, Traumatic
A Trial Evaluating Effects of COMT Inhibition in Patients With Acquired Brain Injury
This is a follow-up study for an ongoing open label trial conducted by the Sheppard Pratt-Lieber Research Institute utilizing the catechol-O-methyl-transferase (COMT) inhibitor Tolcapone to evaluate its effects on cognition and…
- Conditions
- Brain Injuries, Brain Injuries, Traumatic, Brain Injury, Chronic
- Trial name
- NCT03273062
- Testing
- Tolcapone 200 MG
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sheppard Pratt Health System
PTSD
Primary Care-Based Mindfulness Intervention for Veterans With PTSD
Primary care patients typically do not receive adequate PTSD treatment because of their reluctance to engage in empirically-supported treatments offered in specialty care settings.
- Trial name
- NCT02399696
- Testing
- Primary Care-Brief Mindfulness Program, Primary Care-Treatment as Usual
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Syracuse VA Medical Center
Stress Disorders, Post-Traumatic
Neuroimmunological Model of Traumatic Memory
Traumatic events may lead to strong emotional episodic memories common in Post- Traumatic Stress Disorder(PTSD). Intense affect may inhibit efficacy of glutamatergic neurotransmission in two particular areas of the limbic system…
- Trial name
- NCT00396695
- Testing
- Blood test
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
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