Clinical trials: Traumatic Injuries
Traumatic Brain Injury
The RETINA Project: Reliable Eye Tracking in Neurocognitive Assessment of Traumatic Brain Injury
The purpose of this study is to develop and validate eye-tracking measures that can be used to evaluate neurocognitive dysfunction among individuals with traumatic brain injury (TBI).
- Trial name
- RETINA (NCT01552577)
- Where
- United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
PTSD
Reconsolidation and EMDR
Blocking of reconsolidation by pharmacological or behavioral means offers the therapeutic possibility of weakening traumatic memories in posttraumatic stress disorder (PTSD).
- Trial name
- NCT02572830
- Testing
- Delayed Bilateral Eye Movements, Undelayed Bilateral Eye Movement
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Acquired Brain Injury, Stroke
TMS-EEG for Cortical Excitability
This research study is being done to look at the safety and diagnostic benefit of conducting an TMS(transcranial magnetic stimulation)-EEG measured before and after a brief experimental stimulation session using investigational…
- Conditions
- Acquired Brain Injury, Stroke, Traumatic Brain Injury, Healthy
- Trial name
- NCT05472363
- Testing
- Electroencephalogram, Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Psychological Trauma, Mental Health
Collaborative Organizational Approach to Selecting and Tailoring Implementation Strategies
The purpose of this study is to partner with the North Carolina Child Treatment Program (NC CTP) and the SAMHSA-funded National Child Traumatic Stress Network (NCTSN) to develop and pilot the Collaborative Organizational Approach…
- Trial name
- COAST-IS (NCT03799432)
- Testing
- COAST-IS, TF-CBT Learning Collaborative
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Soft Tissue Injuries
Study to Determine if Shock Wave Therapy Applied to Traumatic Wounds of the Extremity Improves Healing Time
The purpose of this study is to determine if adding shock wave therapy to standard-of-care wound treatment for traumatic extremity wounds helps them heal faster.
- Trial name
- CWI (NCT00486733)
- Testing
- DermaGold
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Suicide and Depression
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Despite increasing suicide rates in adolescents, there remains a paucity of approaches to use to prevent re-attempts. Any hope for breaking the code to prevent youth suicide lies in understanding biological factors that play a…
- Trial name
- NCT04783506
- Testing
- Observational Study
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Mild Traumatic Brain Injury
High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury
Aim 1: To use magnetoencephalography (MEG) and magnetic resonance imaging (MRI) in Veterans and civilians with mild traumatic brain injury (mTBI) and sensory postconcussive symptoms (PCS) to demonstrate the mechanism of…
- Trial name
- NAVIGATE-TBI (NCT03799458)
- Testing
- Active High-definition transcranial direct current stimulation (HD-tDCS)
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Traumatic Brain Injury
Augmented Reality and Treadmill Training After Traumatic Brain Injury
Up to 40 participants will be enrolled in this study in order to obtain complete data on 30 participants. The investigators will be assessing if Augmented reality in combination with treadmill training is safe and feasible to use…
- Trial name
- NCT04553848
- Testing
- Augmented Reality, Treadmill training, Over ground training/standard of care
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Craig Hospital
PTSD, Stress, Psychological
Relief of Symptoms of Post-traumatic Stress for Victims of Gun Violence
To test the hypothesis that adult individuals who are victims of gun violence will have decreased symptoms of post-traumatic stress after an individual-level intervention with the Screening and Tool for Awareness and Relief of…
- Conditions
- PTSD, Stress, Psychological, Gunshot Wound
- Trial name
- NCT03916614
- Testing
- Screening Tool for Relief of Trauma (START), standard of care
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Yale University
Brain Concussion, Post-Concussion Syndrome
Investigating the Physiological, Cognitive, and Psychological Effects of a Cognitive-Based Intervention
The primary purpose of this study is to investigate the effectiveness of a brief mindfulness-based intervention for targeting chronic physiological underarousal and post-concussive symptoms following a mild head injury (MHI), as…
- Trial name
- IPCPE-Mind (NCT02906449)
- Testing
- Meditation Technique
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brock University
Traumatic Birth, Self Efficacy
Effect of Solution-focused Approach Training on Traumatic Birth Perception, Vaginal Birth Self-efficacy, Birth Choice
Women's psycho-social health during pregnancy could influence the course of pregnancy, psychological and emotional life, not only in labor but also during the postpartum period.
- Conditions
- Traumatic Birth, Self Efficacy, Perception, Self
- Trial name
- NCT06155435
- Testing
- solution focused approach training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Mild Traumatic Brain Injury
A Community Support Network Intervention in SOAR Project Intimate Partner Violence-Related Traumatic Brain Injury
Intimate Partner Violence (IPV) comprises physical, sexual and emotional abuse and controlling behaviors imposed by an intimate partner.
- Trial name
- SOAR-CSNI (NCT04890925)
- Testing
- Community Support Network (CSN) intervention, Usual care
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ptsd
PTSD Interview Regarding Future Study Design and Equipment.
To gain insight and perspective unique to individuals with a diagnosis of PTSD, this study will utilize an experiential one-to-one interview format.
- Trial name
- NCT05276115
- Testing
- Interview
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Life University
PTSD
Losartan and Memory
This study investigates the effect of a single dose of 50mg losartan vs placebo on BOLD signal during memory encoding.
- Trial name
- NCT05828940
- Testing
- Losartan Potassium
- Where
- United Kingdom
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Posttraumatic Stress Disorder
Stepped Care for Children After Trauma: Optimizing Treatment
Children who are exposed to traumatic events are at risk for developing PTSD and other mental health problems. Although effective treatments for childhood PTSD exist, service delivery approaches that are more accessible…
- Trial name
- NCT02537678
- Testing
- Stepped Care TF-CBT, Standard TF-CBT
- Where
- 6 sites in United States
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Trauma, Brain
Caregiver Wellness After Traumatic Brain Injury (CG-WELL): An Intervention Designed to Promote Well-being in Caregivers of Acute Moderate to Severe Traumatic Brain Injuries
After injury, survivors of msTBI depend on informal family caregivers. Upwards of 77% of family caregivers experience poor outcomes, such as adverse life changes, poor health related quality of life, and increased depressive…
- Trial name
- CG-Well (NCT05307640)
- Testing
- CG-Well, Information Support & Referral (ISR)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Natalie Kreitzer
Acute Stress Symptoms, Sexual Violence
The Effectiveness of a Brief Early Intervention of Acute Stress Syndrome Stabilization Protocol for Victims of Sexual Violence (ASSYST-SV).
TThe main objectives of this research project are twofold: (1) to conduct a narrative review of the scientific literature on the efficacy and effectiveness of psychological interventions for reducing acute post-traumatic stress…
- Trial name
- ASSYST-SV (NCT07112040)
- Testing
- Behavioral - ASSYST-VS Protocol
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Diabetes, Depression
Self-Efficacy Enhancing Interviewing Techniques Study
Patient self-efficacy, or confidence in one's ability to take the necessary steps to achieve a goal, has been shown to influence a number of important health behaviors and outcomes.
- Conditions
- Diabetes, Depression, Anxiety, Asthma
- Trial name
- SEE-IT (NCT00643435)
- Testing
- Self-efficacy enhancing interviewing techniques training, Control intervention
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Musculoskeletal Injury
Post-Concussion Musculoskeletal Injury Risks
Musculoskeletal injuries (MSKI) and traumatic brain injury (TBI) are the signature injuries of the ongoing military conflicts. MSKI affect 800,000 Service Members annually and TBI have impacted more than 350,000 in the past 19…
- Trial name
- NCT05122728
- Testing
- Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment
- Where
- 3 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Posttraumatic Stress Disorder, Reintegration
Evaluation of ProVetus/Sponsorship Initiative
Some Veterans who recently served in the military report significant psychological problems based on their experiences in the military.
- Conditions
- Posttraumatic Stress Disorder, Reintegration, Social Support
- Trial name
- NCT02627612
- Testing
- Pro Vetus, Team Red, White, and Blue (TM RWB)
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
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