Clinical trials: Traumatic Injuries
Pregnancy Early, PTSD
PTSD Screening in Pregnant Black Women
This study will compare the effectiveness of two active screening interventions in improving post-traumatic stress disorder (PTSD) symptoms, maternal perinatal care utilization, satisfaction utilization of mental healthcare…
- Trial name
- NCT06522022
- Testing
- Culturally Responsive SBIRT for OB, Brief Screening for PTSD
- Where
- 2 sites in United States
- Volunteers
- 804 people, healthy volunteers welcome
- Sponsor
- Emory University
Traumatic Brain Injury, Post-traumatic Epilepsy
Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)
The overarching goal of this study is to improve understanding of the long-range natural history of TBI and post-traumatic epilepsy (PTE) by extending follow-up of a previously enrolled cohort (TRACK-TBI) beyond the first 12…
- Trial name
- NCT05823766
- Testing
- In-Person Outcome Assessment, 3T Magnetic Resonance Imaging (MRI), Clinical Visit
- Where
- 9 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stress Disorder, Stress
Sensate II Utilization and Perceived Stress in Adults
Sensate® is A commercially marketed (FCC #: 2AS9ESEN231) stress management wellness device (BioSelf Technology; London, UK). This non-invasive wellness device is one component of a cross-modal (acoustic and aural) sensory…
- Trial name
- NCT05519995
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- BioSelf Technology
Hemianopia, Hemianopsia
Collision Warning Device for Blind and Visually Impaired
This study evaluates a novel collision warning device to help people with severe vision impairment or blindness avoid collisions with obstacles.
- Conditions
- Hemianopia, Hemianopsia, Peripheral Visual Field Defect, Blindness
- Trial name
- NCT03057496
- Testing
- Collision warning device
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Alzheimer Disease, Chronic Traumatic Encephalopathy
Visualizing Brain Proteinopathies Using [F-18]Flornaptitril-PET in the Prediction of Clinical Progression of Mild Cognitive Impairment With Either Suspected Chronic Traumatic Encephalopathy or Alzheimer's Disease
CMK-0301 is a multi-site, randomized clinical trial to evaluate the safety and efficacy of [F-18]Flornaptitril-PET (F-18 FNT-PET) for the prediction of clinical progression of Mild Cognitive Impairment (MCI) with either Suspected…
- Trial name
- NCT06254469
- Testing
- [F-18]Flornaptitril
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- CereMark Pharma, LLC
Acquired Brain Injury
SAFIR© : An Early Intervention for Supporting Families of Patients With Acquired Brain Injuries
The aim of the study is to evaluate the feasibility of a newly developed intervention to improve family support for patient with acquired brain injury (ABI) in early phase of hospitalization (SAFIR): the main components are the…
- Trial name
- SAFIR© (NCT04138524)
- Testing
- SAFIR©
- Where
- Switzerland
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Brain Injuries, Concussion, Mild
Evaluation and Validation of a Multimodal Brain Function Biomarker With NPC
This study is designed to collect data which will be used to associate changes in EEG, neurocognitive performance, eNPC and clinical symptoms in concussion subtypes.
- Conditions
- Brain Injuries, Concussion, Mild, Concussion, Brain, Near Point Convergence
- Trial name
- BSC-CI-NPC (NCT04074486)
- Testing
- BrainScope Ahead 300iP-O, SCAT5, Near Point Convergence
- Where
- 6 sites in United States
- Volunteers
- 1,318 people, healthy volunteers welcome
- Sponsor
- BrainScope Company, Inc.
Chronic Posttraumatic Stress Disorder
Enhancing Exposure Therapy for Post-traumatic Stress Disorder
This study is investigating a new brief psychotherapy for post-traumatic stress disorder (PTSD) which, modifies an already proven psychotherapy for PTSD by adding two new components and modifying several others.
- Trial name
- NCT01574118
- Testing
- Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Anxiety Disorders, Depressive Disorder
Transdiagnostic Treatment Personalization
The primary purpose of this study is to explore whether the efficiency of treatment for anxiety and depressive disorders can be increased using two discrete strategies: personalized skill ordering and 2) treatment discontinuation…
- Conditions
- Anxiety Disorders, Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04584879
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Traumatic Brain Injury, Intracranial Hemorrhages
Efficacy and Feasibility Trial of a Portable Near Infra-Red Hematoma Imager (NIRD-HI)
Traumatic Brain Injury (TBI) is a leading cause of death and disability among military personnel, Veterans, and civilians. One of the most dangerous complications of moderate-to-severe TBI is intracranial hemorrhage (ICH).
- Conditions
- Traumatic Brain Injury, Intracranial Hemorrhages, Combat Casualty Care, Point of Care
- Trial name
- NIRD-HI (NCT07338383)
- Testing
- NIRD-HI scan at the time of enrollment, Secondary NIRD-HI scan when a planned repeat CT is performed
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Geneva Foundation
Posttraumatic Stress Disorder
Results From a 24 Week Trial of EMDR Combined With Venlafaxine XR
Approximately 150 active duty service members meeting Diagnostic and Statistical Manual version 5 (DSM-5) criteria for posttraumatic stress disorder (PTSD) and scoring 50 or above on the Clinician Administered PTSD Score for…
- Trial name
- EMDRVEN (NCT02433353)
- Testing
- Venlafaxine XR, EMDR
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bayne-Jones Army Community Hospital
Spinal Cord Injury
Biomarkers of Spontaneous Recovery From Traumatic Spinal Cord Injury
The purpose of the study is to profile biochemical responses and measure functional recovery in parallel, throughout the 1st year after spinal cord injury (SCI), within the same participants.
- Trial name
- SCIMARK (NCT02731027)
- Where
- 6 sites in United States, Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Traumatic Brain Injury
Oculomotor Assessment of Traumatic Brain Injury (TBI)
The purpose of the proposed study is to compare the sensitivity and specificity of three oculomotor test devices in normal subjects versus subjects with history of TBI.
- Trial name
- NCT03156010
- Testing
- Neuro Kinetics IPAS, Oculogica EyeBox, SyncThink EyeSync Device
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Conflict, Interparental, Trauma, Psychological
Intensive Trauma Treatment for Children Exposed to Parental Conflict
The purpose of this study is to track outcomes of the investigator's therapy approach with children of separation/divorce who have been exposed to parental conflict.
- Trial name
- NCT03271346
- Testing
- intensive trauma-focused therapy
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Trauma Institute & Child Trauma Institute
Post-Traumatic Stress Disorder
Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma
This medical study is an assessment of clinical response in women with Posttraumatic Stress Disorder (PTSD) due to domestic violence or rape trauma when treated with risperidone.
- Trial name
- NCT00208182
- Testing
- Risperidone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Creighton University
Infection, Obstetric Labor Complications
Vaginal Preparation and Azithromycin to Reduce Post Cesarean Infections
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- Conditions
- Infection, Obstetric Labor Complications, Endometritis, Cesarean Delivery Affecting Fetus
- Trial name
- NCT04163679
- Testing
- Vaginal Preparation
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Womack Army Medical Center
Brain Concussion, Mild Traumatic Brain Injury
Neuromodulation and Neuroimaging in Older Children With Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) often causes persistent motor and cognitive deficits in children resulting in functional limitations.
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Motor Disorders, Cognitive Impairment
- Trial name
- CI-tDCS (NCT05762796)
- Testing
- tDCS in Youth with mild traumatic brain injury
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Concussion, Brain, Concussion; Eye
Is Y-Balance Test Predictive of Concussion
The Y Balance Test for the lower quarter (YBT-LQ) is a movement screen used to assess an athlete's risk for injury. The YBT-LQ is a dynamic balance test where the participant stands on a single leg and with the opposite lower…
- Trial name
- NCT05344703
- Testing
- Y Balance Plus Visual Perturbations, Y balance
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Arkansas Colleges of Health Education
Attendance at Treatment, PTSD, Substance Use, and Attendance at Treatment
Evaluation and Treatment of Substance Abuse in Veterans With PTSD Disability Claims
Veterans can apply for compensation and pension (C \& P) benefits for a disability related to military service. The application exam for these benefits provides an opportunity for Veterans returning from service to access VA…
- Trial name
- SBIRT-PTSD (NCT01597856)
- Testing
- SBIRT
- Where
- 2 sites in United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Traumatic Brain Injury, Post-Traumatic Stress Disorder
Multimodal Neurodiagnostic Imaging of Traumatic Brain Injury and Post-Traumatic Stress Disorder
The purpose of this study is to determine whether the brains of persons with and without traumatic brain injury differ in a meaningful way when advanced technology images of the brain are taken using three newer technologies that…
- Trial name
- SANIC (NCT01075035)
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- St. Louis University
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