Clinical trials: Traumatic Injuries
Intrusive Thought, Psychological Trauma
Towards a Post-exposition Pharmacological Prophylaxis for Post-traumatic Stress Disorder
In this study, we investigate the role that deep sleep plays in the prevention of posttraumatic stress disorder after someone has been exposed to a trauma by boosting deep sleep with two drug conditions compared to placebo…
- Conditions
- Intrusive Thought, Psychological Trauma, Inflammatory Response, Physiological Stress
- Trial name
- TRAUMA-PRO (NCT04508166)
- Testing
- Dexmedetomidine, Gamma-Hydroxybutyrate, Experimental Model Trauma Film
- Where
- Switzerland
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Psychiatric University Hospital, Zurich
Concussion (Diagnosis), MTBI - Mild Traumatic Brain Injury
BCAAs in Concussion 3.0
This study is a randomized, placebo-controlled, double-blinded, therapeutic exploratory clinical trial of branched chain amino acids (BCAAs) in the treatment of concussion.
- Conditions
- Concussion (Diagnosis), MTBI - Mild Traumatic Brain Injury, Concussion, Brain, Concussion
- Trial name
- NCT07670195
- Testing
- BCAA
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Akiva Cohen
Stress Disorders, Post-Traumatic
Propranolol Reactivation Mismatch (PRM) Treatment for PTSD
The aim of the proposed work is to gather pilot data from an attempt to enhance the ability of propranolol reactivation (PR) to improve PTSD symptoms by incorporating into the design a mismatch (PRM) between what is expected and…
- Trial name
- NCT03652922
- Testing
- Reactivation Mismatch
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder, Sleep Deprivation
Explanation About Sleep in Post Trauma Patients
This study is designed to test the effect of an explanation about the first sleep following trauma exposure, on the development of Post Traumatic Stress Disorder (PTSD) in the months following the traumatic event.
- Trial name
- NCT01684085
- Testing
- Explanation encouraging sleep, Explanation discouraging sleep, Lorazepam
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Central Auditory Processing Disorder, Traumatic Brain Injury
Central Auditory Processing Disorders Associated With Blast Exposure
The incidence of central auditory dysfunction in war fighters who are exposed to high-explosive blasts while serving in combat have not been clearly determined.
- Conditions
- Central Auditory Processing Disorder, Traumatic Brain Injury, Hearing Loss
- Trial name
- NCT00554801
- Testing
- Audiological testing
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Trauma, Injury Traumatic
Trauma Follow-Up Prediction (Project 2: Aim 1)
Traumatic injury and inadequate follow-up care are a significant cause of morbidity and 10% of all deaths in sub-Saharan Africa (SSA).
- Conditions
- Trauma, Injury Traumatic, Injuries
- Trial name
- NCT05430165
- Testing
- Standard mHealth screening (triage) tool
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Mefire Alain Chichom
Psychological Trauma, PTSD
Study of Yoga and Mindfulness for Psychological and Physical Wellness
The study rationale is to analyze the extent to which adult U.S. or non U.S. veterans or active duty military personnel who participate in the Yoga for Men (YfM) online Yoga and meditation classes report changes in symptoms of…
- Trial name
- NCT03059095
- Testing
- Yoga & Meditation
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Post Traumatic Stress Disorder, Alcohol Use Disorder
FAAH Availability in Psychiatric Disorders: A PET Study
The aim of the present study is to examine Fatty Acid Amide Hydrolase (FAAH) availability in humans, including healthy individuals and across a spectrum of psychiatric disorders in which alterations in the endocannabinoid system…
- Conditions
- Post Traumatic Stress Disorder, Alcohol Use Disorder, Psychosis
- Trial name
- NCT04404712
- Testing
- [11C]MK-3168
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Post Traumatic Stress Disorder
Neural Control and Cardiac-Vascular Function in Women With PTSD (VA Psychological Assessment)
The purpose of this research is 1) to investigate the role of the sympathetic nervous system and cardiac-vascular function in women with PTSD; and 2) to determine whether lifestyle modifications (exercise training and healthy…
- Trial name
- NCT03929939
- Testing
- Exercise training and healthy eating (overseen by IEEM research team)
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- North Texas Veterans Healthcare System
Psychiatric Disorder, Trauma, Psychological
Pedopsychiatric and Multidisciplinary Research Devoted to Children Exposed to the Attack in Nice on July 14, 2016
On July 14, 2016, in Nice, children and their families were attacked by the organization "EI". In Nice, 86 deaths, including 10 children, the youngest at 4, were recorded.
- Trial name
- Program14-7 (NCT03356028)
- Testing
- Child and adolescent psychiatry and Epidemiology, salivary biological collection, qualitative analysis of the discourse
- Where
- France
- Volunteers
- 728 people, healthy volunteers welcome
- Sponsor
- Fondation Lenval
Healthy, Stress, Psychological
Study of Physical Health for Women With Posttraumatic Stress or Depression
The purpose of this study is to obtain a better understanding of how stress is related to health risks.
- Conditions
- Healthy, Stress, Psychological, Depression, Posttraumatic Stress Disorders
- Trial name
- NCT01208844
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Anxiety Disorder, PTSD
Peer-led Group Intervention for Coping With Disaster
The present project partners with leading faith communities in Houston to provide expert-led educational workshops to a diverse sample of adults on normative and concerning response to disaster.
- Conditions
- Anxiety Disorder, PTSD, Depressive Symptoms, Anger
- Trial name
- NCT03907995
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Loss of Consciousness of Unspecified Duration, Cerebral Laceration and Contusion
The Clinical Research on the Relationship Between Circadian Rhythm and Gut Microbiota in TBI Patients
Microbiome studies may be highlighted as crucial in the development of sleep disorder for TBI patients. The microbiota-gut-brain connection may further provide an opportunity for microbiota manipulation to treat the TBI patients…
- Conditions
- Loss of Consciousness of Unspecified Duration, Cerebral Laceration and Contusion, Traumatic Brain Injury
- Trial name
- NCT02849028
- Testing
- sleep disorder
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Mild Traumatic Brain Injury
The Use of Anti-oxidants to Reduce Sequela of Mild Traumatic Brain Injury (mTBI) After Blast Exposure
The administration of N-acetyl-cysteine (an anti-oxidant) for seven days along with observation will result in improved hearing and balance function in individuals who demonstrate these disorders after blast exposure when…
- Trial name
- NCT00822263
- Testing
- N-acetyl-cysteine (NAC)
- Where
- Iraq
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
PTSD and Trauma-related Symptoms, Cognitive Decline in Older Adults
Acute Effects of Estradiol Administration on Brain Function During Fear Learning
The goal of current study is to better understand how fear is processed in the brain and how these processes are influenced by cognition and hormones.
- Conditions
- PTSD and Trauma-related Symptoms, Cognitive Decline in Older Adults, Post Menopausal Women
- Trial name
- EstroFearGen (NCT07737613)
- Testing
- estradiol
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Dental Trauma, Enamel Hypoplasia
Evaluation of Sequelae in Permanent Successors Following Traumatic Injuries to Primary Teeth
Retrospective data analysis of children with primary dental trauma and follow-up visual examination to find out the sequelae.
- Conditions
- Dental Trauma, Enamel Hypoplasia, Sequelae, Sequelae Successors
- Trial name
- NCT07134348
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Zeynep Aslı GÜÇLÜ
Traumatic Brain Injury
Anosognosia Evaluation After Cranocerebral Trauma Moderate to Severe
This study is conducted over 18 months. The main objective of this study is to test and compare the relevance and reliability of different tools for measuring the anosognosia.
- Trial name
- ANOSOGNOSIA (NCT02333006)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Activity, Motor, Emotion Regulation
Moving Forward Together 2.0: An Activity Intervention
The study will test whether an online physical activity program that includes mindfulness can increase activity in women who have been abused by a relationship partner.
- Trial name
- MFT (NCT06502444)
- Testing
- Moving Forward Together Activity Intervention
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rosalind Franklin University of Medicine and Science
Preterm Delivery
Factors Associated With Post-Traumatic Stress Disorder in Patients With After Preterm Delivery
Each year in France, between 50,000 and 60,000 children are born prematurely (< 37 weeks of amenorrhea). Literature has shown that preterm deliveries can be associated with the development of PTSD (Post-Traumatic Stress Disorder)…
- Trial name
- PTSD-preterm (NCT03344471)
- Testing
- Passation of questionnaires
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Trauma, Psychological
Systematic Case Series Investigating Eye Movement Desensitization Reprocessing (EMDR) Efficacy With Childhood Sexual Abuse Survivors
This study investigates the effectiveness of EMDR for survivors of childhood sexual abuse. All participants will undertake a standard course of EMDR via the National Heath Service program, alongside a number of questionnaires and…
- Trial name
- EMDR (NCT03966963)
- Testing
- Eye Movement Desensitization Reprocessing (EMDR)
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Salford
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