Clinical trials: Traumatic Injuries
Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion
Central Programming in Patients With a Bionic Hand After Traumatic Brachial Plexus Injury
Traumatic brachial plexus lesions may lead to permanent impairment of hand function despite brachial plexus surgery. In selected cases the affected forearm can be amputated and replaced by a bionic hand.
- Conditions
- Brachial Plexus Neuropathies, Traumatic Brachial Plexus Lesion, Bionic Hand Reconstruction
- Trial name
- NCT04649749
- Testing
- MRI
- Where
- Austria
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Tendon Injury - Hand
Tranexamic Acid Effect on Digit Function Following Primary Repair of Traumatic Digit Flexor Tendon Injuries
This study evaluates the effect of pre-operative treatment with IV Tranexamic Acid on post-operative digit function, in patients that underwent surgical repair of traumatic zone 1 or zone 2 digit flexor tendon tear.
- Trial name
- NCT04178655
- Testing
- Tranexamic acid injection
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
PTSD
Patient Outcome Reporting for Timely Assessments of Life With Post-Traumatic Stress Disorder
This study aims to implement and evaluate a more timely approach to post-traumatic stress disorder (PTSD) diagnosis and management, entitled Patient Outcome Reporting for Timely Assessments of Life with Post-Traumatic Stress…
- Trial name
- PORTAL-PTSD (NCT06479447)
- Testing
- PORTAL-PTSD
- Where
- 2 sites in United States
- Volunteers
- 17,000 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Borderline Personality Disorder, Depressive Disorder
Systematic Use of Telepsychiatry for Outpatients
Implementation and evaluation of video consultation in psychiatric outpatient treatment. The study will focus on patients' experiences regarding the use of VC.
- Conditions
- Borderline Personality Disorder, Depressive Disorder, Ptsd, Anxiety Disorders
- Trial name
- NCT05516238
- Testing
- Case management
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Psychiatric Research Unit, Region Zealand, Denmark
PTSD
Virtual Reality Exposure Therapy for Combat
This non inferiority trial will compare Prolonged Exposure with Virtual Reality Exposure Therapy in adult patients with combat related PTSD.
- Trial name
- VRET (NCT03000478)
- Testing
- Prolonged Exposure, Virtual Reality Exposure Therapy
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
PTSD
Neurofeedback With Real-Time fMRI for Treatment of PTSD
PTSD is a debilitating and costly condition and currently available treatment options have risks and limitations that necessitate development of novel interventions.
- Trial name
- NCT03243149
- Testing
- fMRI - GE Medical System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Duke University
PTSD
Implementation of Prolonged Exposure in the Military
This randomized study examines how prolonged exposure (PE) therapy, an evidence-based treatment for posttraumatic stress disorder (PTSD), can be successfully disseminated and implemented in the Army.
- Trial name
- NCT02982538
- Testing
- Extended Training in Prolonged Exposure Therapy for PTSD, Standard Training in Prolonged Exposure Therapy for PTSD
- Where
- 3 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Traumatic Dental Injury, Autism Spectrum Disorder
Occurrence of Traumatic Dental Injury in a Group of Egyptian Autistic Children Compared to Normal Children: (A Cohort Study)
The aim of the study is to assess the occurrence of traumatic dental Injury in a group of Egyptian Autistic Children compared to normal children. Population: Egyptian children Exposure: Autistic children.
- Conditions
- Traumatic Dental Injury, Autism Spectrum Disorder, Dental Trauma
- Trial name
- NCT04235543
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Posttraumatic Stress Disorder, Chronic Pain
Enhancing Cognitive Processing Therapy for Posttraumatic Stress Disorder Via Stellate Ganglion Block Treatment: A Pilot Trial
Cognitive Processing Therapy (CPT) is an effective first-line, evidence-based treatment for posttraumatic stress disorder (PTSD).
- Trial name
- SGB (NCT05534126)
- Testing
- Stellate Ganglion Block Treatment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Brain Injury, Chronic, Brain Injuries, Traumatic
Traumatic Brain Injury and the Gut Microbiome
The purpose of the study is to determine whether administration of a prebiotic, inulin, can improve the symptom complex associated with traumatic brain injury and whether inulin administration can alter the bacteria that live in…
- Trial name
- NCT04949607
- Testing
- Inulin fructooligosaccharide
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Centre for Neuro Skills
Traumatic Brain Injury, Hearing Loss
Improving Speech in Noise Using Noninvasive Stimulation
Traumatic brain injury, a common injury in military service personnel, often leads to poor processing of speech in noisy environments.
- Trial name
- NCT07176936
- Testing
- Cymba Conchae stimulation, Earlobe stimulation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Florida
Mild Traumatic Brain Injury, Acute Brain Injury
Aerobic Exercise for Concussion
The use of aerobic exercise treatment in the chronic phase of concussion recovery is well-described in the literature but there are limited existing data on the effect of exercise treatment in the acute phase after sport-related…
- Conditions
- Mild Traumatic Brain Injury, Acute Brain Injury, Brain Concussion
- Trial name
- NCT02959216
- Testing
- Aerobic Exercise, Stretching Exercise
- Where
- 3 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Trauma Injury, Child, Only
Using mHealth to Improve Emotional Recovery After Pediatric Injury
Nearly 300,000 U.S. children experience injuries that require them to be hospitalized this year. These children, and their caregivers, are at high risk for emotional and behavioral problems, as well as poor quality of life.
- Conditions
- Trauma Injury, Child, Only, Posttraumatic Stress Disorder, Parents
- Trial name
- NCT04579198
- Testing
- Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
PTSD - Post Traumatic Stress Disorder
Rapid Recovery: Gut Microbiome Correction for PTSD
This cohort clinical trial (RAPID RECOVERY) investigates the role of gut microbiome in mental health and the effectiveness of personalized microbiome correction in individuals with post-traumatic stress disorder (PTSD).
- Trial name
- RAPID RECOVERY (NCT07623967)
- Testing
- Investigational Probiotic Preparation
- Where
- Ukraine
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Uzhhorod National University
Augmented Renal Clearance, Critical Illness
Incidence and Associated Risk Factors of ARC in the Trauma Critically Ill Older Than 50 Years Old
This single-center prospective cohort study conducted at the adult trauma ICU of the Montreal General Hospital (MGH) affiliated with the McGill University Health Centre (MUHC) aims to determine the incidence and associated risk…
- Conditions
- Augmented Renal Clearance, Critical Illness, Polytrauma, Traumatic Brain Injury
- Trial name
- NCT04766944
- Testing
- No intervention
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Epilepsy, Migraine
Clinical Applications of High-Frequency Oscillations
The objective of this study is to utilize high-frequency brain signals (HFBS) to localize functional brain areas and characterize HFBS in epilepsy, migraine, and other brain disorders.
- Conditions
- Epilepsy, Migraine, Headache, Pain
- Trial name
- HFOs (NCT00600717)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Severe Traumatic Brain Injury, Trauma
Impact of Severe Brain Injury on Neuro-vascular and Endothelial Regulation of Peripheral Microcirculation.
Severe brain injury (SBI) is one of the world's leading causes of death and disability in young adults, but its peripheral vascular consequences in humans are poorly understood.
- Trial name
- MicroTC (NCT04597879)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Posttraumatic Stress Disorder, Post-Traumatic Stress Disorder
Geodon (Ziprasidone) for Posttraumatic Stress Disorder
Atypical antipsychotics have shown promise in the treatment of depression and anxiety, which are prominent symptoms of PTSD. The profile of the atypical antipsychotic, ziprasidone (Geodon), suggests possible anxiolytic and…
- Conditions
- Posttraumatic Stress Disorder, Post-Traumatic Stress Disorder, PTSD
- Trial name
- NCT00208208
- Testing
- Ziprasidone
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Creighton University
Stress Disorders, Post-Traumatic
Identifying Toddlers and Their Parents Who Are Suffering From Posttraumatic Distress Following War and Terror
The project is aimed at identifying children who are suffering from posttraumatic distress and increasing capacity to provide treatment for them and for their caretakers.
- Trial name
- NCT00600418
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Herzog Hospital
Mindfulness, Educational Support
Adaptation of Mindfulness Training to Treat Moral Injury in Veterans
This project is highly innovative as it will be the first to develop a mindfulness-based treatment as a first-line intervention tailored to target moral injury among combat-wounded veterans.
- Trial name
- NCT05341882
- Testing
- Mindfulness, Educational Support
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Old Dominion University