Clinical trials: Traumatic Injuries
MTBI - Mild Traumatic Brain Injury
Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders
The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems.
- Trial name
- NCT07282691
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Salus University
Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury
High-Intensity Peripheral Magnetic Stimulation in Traumatic Peripheral Nerve Injury
Traumatic peripheral nerve injury is a common cause of chronic neuropathic pain, muscle weakness, and functional limitation, particularly in young and active individuals.
- Conditions
- Peripheral Nerve Injuries, Traumatic Peripheral Nerve Injury, Neuropathic Pain, Peripheral Nerve Injuries, Traumatic
- Trial name
- NCT07705490
- Testing
- High-Intensity Peripheral Magnetic Stimulation, Therapeutic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Traumatic Brain Injuries
Validation and Standardisation of a "Neuralix" Digital Ecological Battery
The management of head trauma patients requires the assessment of cognitive disorders using standardized neuropsychological tests and questionnaires.
- Trial name
- VANOLIX (NCT06830291)
- Where
- France
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Traumatic Brain Injury
Brain Injury Assessment Study at Hennepin County Medical Center
The goals of this study are to develop an objective, multi-modal classification scheme and outcome measures for traumatic brain injury based on several measures: (1) blood-based biomarkers (indicates which cell types are…
- Trial name
- BASH (NCT02706574)
- Volunteers
- 774 people, healthy volunteers welcome
- Sponsor
- CentraCare
Traumatic Brain Injury (TBI), Hazardous and Harmful Alcohol Use
Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI
The goal of the proposed project is to improve the treatment of veterans with co-occurring traumatic brain injury (TBI) and hazardous or harmful alcohol use.
- Trial name
- VAT (NCT01750268)
- Testing
- Medical Management Counseling, Topiramate
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder
Examining an Emergency Room Intervention for the Prevention of Post Traumatic Stress Disorder (PTSD)
PTSD is a common and distressing possible outcome following exposure to a traumatic event. Recent studies show that memory processes may be central to the development of the disorder, and interrupting the consolidation of…
- Trial name
- NCT01162044
- Testing
- Computer game
- Where
- Israel
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Traumatic Intracranial Hemorrhage, Traumatic Brain Injury
No Cases of Delayed Intracranial Hemorrhage (d-ICH) Among Patients With Mild Traumatic Brain Injury (mTBI) on Oral Anticoagulation Therapy
Abstract Purpose Patients with anticoagulation therapy has a higher risk of developing traumatic Intracranial Hemorrhage (tICH).
- Trial name
- NCT05609734
- Testing
- no intervention, only observational retrospective study
- Where
- Sweden
- Volunteers
- 249 people
- Sponsor
- Umeå University
Chronic Subdural Hematoma
Adjuvant Tranexamic Acid (TXA) Versus Surgery Alone for Adult Patients With Chronic Subdural Hematoma (CSDH)
This study is an open label randomized controlled trial. Patients with a symptomatic Chronic Subdural Hematoma (CSDH) confirmed on radiological imaging, planned for surgery, age over 18, free from other intracranial pathologies…
- Trial name
- RATATA (NCT07245264)
- Testing
- Tranexamic Acid (Cyklokapron)
- Where
- India
- Volunteers
- 274 people
- Sponsor
- St. Olavs Hospital
PTSD
Ultrasonic Neuromodulation for Treatment of PTSD
This study will evaluate a new form of non-invasive deep brain therapy for individuals with post-traumatic stress disorder (PTSD).
- Trial name
- NCT06135064
- Testing
- Diadem
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Mild Traumatic Brain Injury
PROtein S100B for Mild Trauma of the HEad in Emergency Patients
Brain injury is a frequent purpose for consultation in emergency services. Management of brain injury is time and resource consuming, combining clinical monitoring and imaging.
- Trial name
- PROMETHEE (NCT03313505)
- Testing
- S100B protein dosage, Brain CT scan
- Where
- 15 sites in France, Monaco
- Volunteers
- 787 people
- Sponsor
- Centre Hospitalier Princesse Grace
PTSD
Topiramate in the Treatment of Post Traumatic Stress Disorder (PTSD)
To study the potential therapeutic effects of topiramate (Topamax) in the treatment of PTSD.
- Trial name
- NCT00203463
- Testing
- topiramate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Tuscaloosa Research & Education Advancement Corporation
Traumatic Brain Injury
Efficacy of Ketamine in Children With Severe Brain Injury for Brain Cell Protection
The purpose of this study is to determine the possible effects of an anesthetic agent called Ketamine on the injured brain in children. The researchers think that it will effect the outcomes of children with these injuries.
- Trial name
- NCT00556387
- Testing
- saline, Ketamine
- Sponsor
- University of Arkansas
Quality of Life, Stigma, Social
App-based Psychosocial Intervention to Enhance Quality of Life in Arabic-speaking Refugees Residing in Switzerland
The ongoing warfare and economic instability in the Middle East and in North Africa causes many people to leave their home countries.
- Conditions
- Quality of Life, Stigma, Social, Depression, PTSD
- Trial name
- Sui (NCT05651737)
- Testing
- Sui App (SRK)
- Where
- Switzerland
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Bern
Traumatic Brain Injury, Cognitive Impairment
"Cognitive Rehabilitation With Direct Current Transcranial Stimulation in Post-Traumatic Brain Injury Patients"
The goal of this clinical trial is to investigate the impact of daily self-administered transcranial direct current stimulation (tDCS) therapy on the cognitive function of individuals with moderate to severe cognitive impairment…
- Trial name
- tDCS-TEC (NCT06228872)
- Testing
- Cognitive Computerized Training (CCT) plus Anodic transcranial Direct Current Stimulation (tDCS)
- Where
- Chile
- Volunteers
- 38 people
- Sponsor
- Mutual de Seguridad Hospital Clinico
Ankle Trauma
Evaluation of the Benefits of Ultrasound in Improving the Diagnosis and Management of Injuries the Child's Ankle
Evaluate ankle's ultrasound contribution in the accuracy of ankle's diagnosis of traumatic injuries (objectivated by reference's examination : ankle's MRI)
- Trial name
- ANKLE (NCT03507972)
- Testing
- ankle ultrasound, Member MRI
- Where
- France
- Volunteers
- 97 people
- Sponsor
- University Hospital, Lille
Chimerism, Blood Transfusion
Transfusion-Associated Microchimerism in Individuals Receiving a Blood Transfusion After a Traumatic Injury
Individuals who experience a traumatic injury often have a significant amount of blood loss and may require a blood transfusion.
- Conditions
- Chimerism, Blood Transfusion, Wounds and Injuries
- Trial name
- NCT00400192
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Vitalant Research Institute
Spinal Cord Trauma
Autoimmunity And Immune Deficiency After Spinal Cord Injury: Association With Rehabilitation Outcomes
The SCIentinel-prolong study systematically analyzes humoral autoantibody responses and thier interaction with post-spinal cord injury (SCI) immune-deficiency and infections as well as their association with the clinical course…
- Trial name
- NCT04211636
- Volunteers
- 81 people
- Sponsor
- Marcel Kopp, MD
Traumatic Brain Injury
Ischemia Modified Albumin in Traumatic Brain Injury
In the current study the investigators intend to evaluate the role of Ischemia modified albumin (IMA) in the prediction of poor outcome in patients with traumatic brain injury (TBI).
- Trial name
- NCT03637101
- Testing
- Ischemia modified albumin (IMA)
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Kasr El Aini Hospital
Gunshot Wound
Epidemiology of Gunshot Wounds Injuries Admitted in ICU in France
In civilian practice, the incidence of firearm violence depends on the country. In high income countries, most cases are reported in the USA or South Africa.
- Trial name
- GSW_in_ICU (NCT05224570)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
PTSD
Acupuncture and Mindfulness Based Stress Reduction for Wellness
AMWELL is a randomized, waitlist-controlled, pilot study to evaluate the comparative efficacy of Mindfulness Based Stress Reduction (MBSR) and Acupuncture (AT) to Wait-List Control (WL) in adult female survivors of childhood…
- Trial name
- AMWELL (NCT04859686)
- Testing
- Mindfulness-Based Stress Reduction, Acupuncture Treatment
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
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